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Journal Abstract Search

292 related items for PubMed ID: 21824775

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  • 3. Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase.
    Perruchon J, Ortmann R, Altenkämper M, Silber K, Wiesner J, Jomaa H, Klebe G, Schlitzer M.
    ChemMedChem; 2008 Aug; 3(8):1232-41. PubMed ID: 18470849
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  • 5. Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors.
    Bodill T, Conibear AC, Blatch GL, Lobb KA, Kaye PT.
    Bioorg Med Chem; 2011 Feb 01; 19(3):1321-7. PubMed ID: 21216609
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  • 8. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase.
    Zinglé C, Kuntz L, Tritsch D, Grosdemange-Billiard C, Rohmer M.
    J Org Chem; 2010 May 21; 75(10):3203-7. PubMed ID: 20429517
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  • 9. Reverse fosmidomycin derivatives against the antimalarial drug target IspC (Dxr).
    Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Pein MK, Gräwert T, Kaiser J, Bacher A, Eisenreich W, Illarionov B, Fischer M, Maes L, Groll M, Kurz T.
    J Med Chem; 2011 Oct 13; 54(19):6796-802. PubMed ID: 21866890
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  • 10. Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR).
    Abdullaziz MA, Takada S, Illarionov B, Pessanha de Carvalho L, Sakamoto Y, Höfmann S, Knak T, Kiffe-Delf AL, Mazzone F, Pfeffer K, Kalscheuer R, Bacher A, Held J, Fischer M, Tanaka N, Kurz T.
    ACS Infect Dis; 2024 May 10; 10(5):1739-1752. PubMed ID: 38647213
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  • 11. A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
    Mercklé L, de Andrés-Gómez A, Dick B, Cox RJ, Godfrey CR.
    Chembiochem; 2005 Oct 10; 6(10):1866-74. PubMed ID: 16116659
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  • 12. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
    Devreux V, Wiesner J, Jomaa H, Van der Eycken J, Van Calenbergh S.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4920-3. PubMed ID: 17583502
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  • 13. Growth inhibition of Mycobacterium smegmatis by prodrugs of deoxyxylulose phosphate reducto-isomerase inhibitors, promising anti-mycobacterial agents.
    Ponaire S, Zinglé C, Tritsch D, Grosdemange-Billiard C, Rohmer M.
    Eur J Med Chem; 2012 May 01; 51():277-85. PubMed ID: 22405649
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  • 17. Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity.
    Wiesner J, Ortmann R, Jomaa H, Schlitzer M.
    Arch Pharm (Weinheim); 2007 Dec 01; 340(12):667-9. PubMed ID: 17994601
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  • 19. Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR).
    Zinglé C, Kuntz L, Tritsch D, Grosdemange-Billiard C, Rohmer M.
    Bioorg Med Chem Lett; 2012 Nov 01; 22(21):6563-7. PubMed ID: 23025997
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