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Journal Abstract Search


438 related items for PubMed ID: 21832251

  • 1. NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells.
    Shimizu H, Bolati D, Adijiang A, Muteliefu G, Enomoto A, Nishijima F, Dateki M, Niwa T.
    Am J Physiol Cell Physiol; 2011 Nov; 301(5):C1201-12. PubMed ID: 21832251
    [Abstract] [Full Text] [Related]

  • 2. Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate.
    Shimizu H, Bolati D, Adijiang A, Enomoto A, Nishijima F, Dateki M, Niwa T.
    Am J Physiol Cell Physiol; 2010 Nov; 299(5):C1110-7. PubMed ID: 20720180
    [Abstract] [Full Text] [Related]

  • 3. Indoxyl sulfate enhances p53-TGF-β1-Smad3 pathway in proximal tubular cells.
    Shimizu H, Yisireyili M, Nishijima F, Niwa T.
    Am J Nephrol; 2013 Nov; 37(2):97-103. PubMed ID: 23363842
    [Abstract] [Full Text] [Related]

  • 4. CREB, NF-κB, and NADPH oxidase coordinately upregulate indoxyl sulfate-induced angiotensinogen expression in proximal tubular cells.
    Shimizu H, Saito S, Higashiyama Y, Nishijima F, Niwa T.
    Am J Physiol Cell Physiol; 2013 Apr 01; 304(7):C685-92. PubMed ID: 23407882
    [Abstract] [Full Text] [Related]

  • 5. Indoxyl sulfate-induced activation of (pro)renin receptor is involved in expression of TGF-β1 and α-smooth muscle actin in proximal tubular cells.
    Saito S, Shimizu H, Yisireyili M, Nishijima F, Enomoto A, Niwa T.
    Endocrinology; 2014 May 01; 155(5):1899-907. PubMed ID: 24601883
    [Abstract] [Full Text] [Related]

  • 6. Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence.
    Shimizu H, Yisireyili M, Nishijima F, Niwa T.
    Am J Nephrol; 2012 May 01; 36(2):184-9. PubMed ID: 22889746
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  • 8. Indoxyl sulfate upregulates renal expression of ICAM-1 via production of ROS and activation of NF-κB and p53 in proximal tubular cells.
    Shimizu H, Yisireyili M, Higashiyama Y, Nishijima F, Niwa T.
    Life Sci; 2013 Feb 07; 92(2):143-8. PubMed ID: 23201429
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  • 10. Indoxyl sulfate upregulates prorenin expression via nuclear factor-κB p65, signal transducer and activator of transcription 3, and reactive oxygen species in proximal tubular cells.
    Saito S, Yisireyili M, Shimizu H, Ng HY, Niwa T.
    J Ren Nutr; 2015 Mar 07; 25(2):145-8. PubMed ID: 25556305
    [Abstract] [Full Text] [Related]

  • 11. Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB.
    Bolati D, Shimizu H, Yisireyili M, Nishijima F, Niwa T.
    BMC Nephrol; 2013 Mar 04; 14():56. PubMed ID: 23496811
    [Abstract] [Full Text] [Related]

  • 12. Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress.
    Muteliefu G, Shimizu H, Enomoto A, Nishijima F, Takahashi M, Niwa T.
    Am J Physiol Cell Physiol; 2012 Jul 15; 303(2):C126-34. PubMed ID: 22555846
    [Abstract] [Full Text] [Related]

  • 13. Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells.
    Motojima M, Hosokawa A, Yamato H, Muraki T, Yoshioka T.
    Kidney Int; 2003 May 15; 63(5):1671-80. PubMed ID: 12675842
    [Abstract] [Full Text] [Related]

  • 14. Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats.
    Adijiang A, Higuchi Y, Nishijima F, Shimizu H, Niwa T.
    Biochem Biophys Res Commun; 2010 Sep 03; 399(4):637-41. PubMed ID: 20691162
    [Abstract] [Full Text] [Related]

  • 15. Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation.
    Tumur Z, Shimizu H, Enomoto A, Miyazaki H, Niwa T.
    Am J Nephrol; 2010 Sep 03; 31(5):435-41. PubMed ID: 20389059
    [Abstract] [Full Text] [Related]

  • 16. Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells.
    Yisireyili M, Takeshita K, Saito S, Murohara T, Niwa T.
    Nagoya J Med Sci; 2017 Nov 03; 79(4):477-486. PubMed ID: 29238104
    [Abstract] [Full Text] [Related]

  • 17. Paricalcitol attenuates indoxyl sulfate-induced apoptosis through the inhibition of MAPK, Akt, and NF-kB activation in HK-2 cells.
    Park JS, Choi HI, Bae EH, Ma SK, Kim SW.
    Korean J Intern Med; 2019 Jan 03; 34(1):146-155. PubMed ID: 28992684
    [Abstract] [Full Text] [Related]

  • 18. Indoxyl sulfate downregulates expression of Mas receptor via OAT3/AhR/Stat3 pathway in proximal tubular cells.
    Ng HY, Yisireyili M, Saito S, Lee CT, Adelibieke Y, Nishijima F, Niwa T.
    PLoS One; 2014 Jan 03; 9(3):e91517. PubMed ID: 24614509
    [Abstract] [Full Text] [Related]

  • 19. The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage.
    Sfikas A, Batsi C, Tselikou E, Vartholomatos G, Monokrousos N, Pappas P, Christoforidis S, Tzavaras T, Kanavaros P, Gorgoulis VG, Marcu KB, Kolettas E.
    Cell Signal; 2012 Nov 03; 24(11):2007-23. PubMed ID: 22750558
    [Abstract] [Full Text] [Related]

  • 20. Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.
    Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M.
    Am J Physiol Renal Physiol; 2010 Sep 03; 299(3):F568-76. PubMed ID: 20534867
    [Abstract] [Full Text] [Related]


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