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160 related items for PubMed ID: 21840189

  • 1. Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.
    Yu CC, Chiang PC, Lu PH, Kuo MT, Wen WC, Chen P, Guh JH.
    J Nutr Biochem; 2012 Aug; 23(8):900-7. PubMed ID: 21840189
    [Abstract] [Full Text] [Related]

  • 2. Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.
    Chiang PC, Lin SC, Pan SL, Kuo CH, Tsai IL, Kuo MT, Wen WC, Chen P, Guh JH.
    Biochem Pharmacol; 2010 Jan 15; 79(2):162-71. PubMed ID: 19723512
    [Abstract] [Full Text] [Related]

  • 3. Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles.
    Kumar VB, Yuan TC, Liou JW, Yang CJ, Sung PJ, Weng CF.
    Mutat Res; 2011 Feb 10; 707(1-2):42-52. PubMed ID: 21185843
    [Abstract] [Full Text] [Related]

  • 4. Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
    Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb 10; 9():575-601. PubMed ID: 25632225
    [Abstract] [Full Text] [Related]

  • 5. Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells.
    Shrivastava S, Kulkarni P, Thummuri D, Jeengar MK, Naidu VG, Alvala M, Redddy GB, Ramakrishna S.
    Apoptosis; 2014 Jul 10; 19(7):1148-64. PubMed ID: 24729100
    [Abstract] [Full Text] [Related]

  • 6. Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
    Wang F, Wang Q, Zhou ZW, Yu SN, Pan ST, He ZX, Zhang X, Wang D, Yang YX, Yang T, Sun T, Li M, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Jul 10; 9():537-60. PubMed ID: 25632222
    [Abstract] [Full Text] [Related]

  • 7. Methoxychalcone induces cell-cycle arrest and apoptosis in human hormone-resistant prostate cancer cells through PI 3-kinase-independent inhibition of mTOR pathways.
    Sun YW, Huang WJ, Hsiao CJ, Chen YC, Lu PH, Guh JH.
    Prostate; 2010 Sep 01; 70(12):1295-306. PubMed ID: 20623631
    [Abstract] [Full Text] [Related]

  • 8. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
    Peponi E, Drakos E, Reyes G, Leventaki V, Rassidakis GZ, Medeiros LJ.
    Am J Pathol; 2006 Dec 01; 169(6):2171-80. PubMed ID: 17148679
    [Abstract] [Full Text] [Related]

  • 9. Down-regulation of the nuclear factor-kappaB by lidamycin in association with inducing apoptosis in human pancreatic cancer cells and inhibiting xenograft growth.
    Chen J, Ouyang ZG, Zhang SH, Zhen YS.
    Oncol Rep; 2007 Jun 01; 17(6):1445-51. PubMed ID: 17487403
    [Abstract] [Full Text] [Related]

  • 10. Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling.
    Lin JF, Tsai TF, Liao PC, Lin YH, Lin YC, Chen HE, Chou KY, Hwang TI.
    Carcinogenesis; 2013 Feb 01; 34(2):406-14. PubMed ID: 23172666
    [Abstract] [Full Text] [Related]

  • 11. FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.
    Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP.
    J Surg Res; 2001 May 15; 97(2):123-30. PubMed ID: 11341787
    [Abstract] [Full Text] [Related]

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  • 14. mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells.
    Qi M, Zhou H, Fan S, Li Z, Yao G, Tashiro S, Onodera S, Xia M, Ikejima T.
    Eur J Pharmacol; 2013 Sep 05; 715(1-3):76-88. PubMed ID: 23810968
    [Abstract] [Full Text] [Related]

  • 15. The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.
    Vitale G, Zappavigna S, Marra M, Dicitore A, Meschini S, Condello M, Arancia G, Castiglioni S, Maroni P, Bendinelli P, Piccoletti R, van Koetsveld PM, Cavagnini F, Budillon A, Abbruzzese A, Hofland LJ, Caraglia M.
    Biotechnol Adv; 2012 Sep 05; 30(1):169-84. PubMed ID: 21871555
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
    Mochizuki T, Furuta S, Mitsushita J, Shang WH, Ito M, Yokoo Y, Yamaura M, Ishizone S, Nakayama J, Konagai A, Hirose K, Kiyosawa K, Kamata T.
    Oncogene; 2006 Jun 22; 25(26):3699-707. PubMed ID: 16532036
    [Abstract] [Full Text] [Related]

  • 17. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway.
    Saleem M, Kaur S, Kweon MH, Adhami VM, Afaq F, Mukhtar H.
    Carcinogenesis; 2005 Nov 22; 26(11):1956-64. PubMed ID: 15958516
    [Abstract] [Full Text] [Related]

  • 18. Akt inhibitor shows anticancer and radiosensitizing effects in malignant glioma cells by inducing autophagy.
    Fujiwara K, Iwado E, Mills GB, Sawaya R, Kondo S, Kondo Y.
    Int J Oncol; 2007 Oct 22; 31(4):753-60. PubMed ID: 17786305
    [Abstract] [Full Text] [Related]

  • 19. Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.
    Chu PM, Chen LH, Chen MT, Ma HI, Su TL, Hsieh PC, Chien CS, Jiang BH, Chen YC, Lin YH, Shih YH, Tu PH, Chiou SH.
    Cancer Chemother Pharmacol; 2012 Mar 22; 69(3):621-33. PubMed ID: 21947203
    [Abstract] [Full Text] [Related]

  • 20. Molecular mechanism(s) of actinomycin-D induced sensitization of pancreatic cancer cells to CD95 mediated apoptosis.
    Glazyrin AL, Chinni S, Alhasan S, Adsay VN, Vaitkevicius VK, Sarkar FH.
    Int J Oncol; 2002 Jan 22; 20(1):201-5. PubMed ID: 11743665
    [Abstract] [Full Text] [Related]

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