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Journal Abstract Search


221 related items for PubMed ID: 21840902

  • 1. The mitochondrial DNA helicase TWINKLE can assemble on a closed circular template and support initiation of DNA synthesis.
    Jemt E, Farge G, Bäckström S, Holmlund T, Gustafsson CM, Falkenberg M.
    Nucleic Acids Res; 2011 Nov; 39(21):9238-49. PubMed ID: 21840902
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  • 3. Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.
    Wanrooij S, Fusté JM, Farge G, Shi Y, Gustafsson CM, Falkenberg M.
    Proc Natl Acad Sci U S A; 2008 Aug 12; 105(32):11122-7. PubMed ID: 18685103
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  • 4. Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein.
    Rodrigues APC, Oliveira MT.
    Methods Mol Biol; 2021 Aug 12; 2281():313-322. PubMed ID: 33847968
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  • 5. The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function.
    Farge G, Pham XH, Holmlund T, Khorostov I, Falkenberg M.
    Nucleic Acids Res; 2007 Aug 12; 35(3):902-11. PubMed ID: 17251196
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  • 6. Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase.
    Kaur P, Longley MJ, Pan H, Wang W, Countryman P, Wang H, Copeland WC.
    J Biol Chem; 2020 Apr 24; 295(17):5564-5576. PubMed ID: 32213598
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  • 7. TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication.
    Milenkovic D, Matic S, Kühl I, Ruzzenente B, Freyer C, Jemt E, Park CB, Falkenberg M, Larsson NG.
    Hum Mol Genet; 2013 May 15; 22(10):1983-93. PubMed ID: 23393161
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  • 8. Oxidative DNA damage stalls the human mitochondrial replisome.
    Stojkovič G, Makarova AV, Wanrooij PH, Forslund J, Burgers PM, Wanrooij S.
    Sci Rep; 2016 Jul 01; 6():28942. PubMed ID: 27364318
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  • 9. TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease.
    Peter B, Falkenberg M.
    Genes (Basel); 2020 Apr 09; 11(4):. PubMed ID: 32283748
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  • 10. In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication.
    Miralles Fusté J, Shi Y, Wanrooij S, Zhu X, Jemt E, Persson Ö, Sabouri N, Gustafsson CM, Falkenberg M.
    PLoS Genet; 2014 Dec 09; 10(12):e1004832. PubMed ID: 25474639
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  • 11. Reduced stimulation of recombinant DNA polymerase γ and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells.
    Oliveira MT, Kaguni LS.
    J Biol Chem; 2011 Nov 25; 286(47):40649-58. PubMed ID: 21953457
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  • 12. In Vitro Assays of TWINKLE Function.
    Uhler JP, Alexandersson U, Falkenberg M.
    Methods Mol Biol; 2023 Nov 25; 2615():191-201. PubMed ID: 36807793
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  • 13. Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.
    Wanrooij S, Goffart S, Pohjoismäki JL, Yasukawa T, Spelbrink JN.
    Nucleic Acids Res; 2007 Nov 25; 35(10):3238-51. PubMed ID: 17452351
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  • 14. DNA polymerase delta holoenzyme: action on single-stranded DNA and on double-stranded DNA in the presence of replicative DNA helicases.
    Podust VN, Podust LM, Müller F, Hübscher U.
    Biochemistry; 1995 Apr 18; 34(15):5003-10. PubMed ID: 7711022
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  • 20. The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ.
    Johnson LC, Singh A, Patel SS.
    J Biol Chem; 2023 Jan 18; 299(1):102797. PubMed ID: 36528058
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