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241 related items for PubMed ID: 21859974
1. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ. Circulation; 2011 Sep 13; 124(11):1212-22. PubMed ID: 21859974 [Abstract] [Full Text] [Related]
5. Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line. Cunha SR, Mohler PJ. J Biol Chem; 2008 Nov 14; 283(46):31968-80. PubMed ID: 18782775 [Abstract] [Full Text] [Related]
7. Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome. Swayne LA, Murphy NP, Asuri S, Chen L, Xu X, McIntosh S, Wang C, Lancione PJ, Roberts JD, Kerr C, Sanatani S, Sherwin E, Kline CF, Zhang M, Mohler PJ, Arbour LT. Circ Cardiovasc Genet; 2017 Jan 14; 10(1):. PubMed ID: 28196901 [Abstract] [Full Text] [Related]
8. A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. Mohler PJ, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, Priori SG, Keating MT, Bennett V. Proc Natl Acad Sci U S A; 2004 Jun 15; 101(24):9137-42. PubMed ID: 15178757 [Abstract] [Full Text] [Related]
9. Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation. Alsina KM, Hulsurkar M, Brandenburg S, Kownatzki-Danger D, Lenz C, Urlaub H, Abu-Taha I, Kamler M, Chiang DY, Lahiri SK, Reynolds JO, Quick AP, Scott L, Word TA, Gelves MD, Heck AJR, Li N, Dobrev D, Lehnart SE, Wehrens XHT. Circulation; 2019 Aug 20; 140(8):681-693. PubMed ID: 31185731 [Abstract] [Full Text] [Related]
10. Cardiac ankyrins: Essential components for development and maintenance of excitable membrane domains in heart. Cunha SR, Mohler PJ. Cardiovasc Res; 2006 Jul 01; 71(1):22-9. PubMed ID: 16650839 [Abstract] [Full Text] [Related]
14. Ankyrin-B Q1283H Variant Linked to Arrhythmias Via Loss of Local Protein Phosphatase 2A Activity Causes Ryanodine Receptor Hyperphosphorylation. Zhu W, Wang C, Hu J, Wan R, Yu J, Xie J, Ma J, Guo L, Ge J, Qiu Y, Chen L, Liu H, Yan X, Liu X, Ye J, He W, Shen Y, Wang C, Mohler PJ, Hong K. Circulation; 2018 Dec 04; 138(23):2682-2697. PubMed ID: 30571258 [Abstract] [Full Text] [Related]
16. Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. Li N, Timofeyev V, Tuteja D, Xu D, Lu L, Zhang Q, Zhang Z, Singapuri A, Albert TR, Rajagopal AV, Bond CT, Periasamy M, Adelman J, Chiamvimonvat N. J Physiol; 2009 Mar 01; 587(Pt 5):1087-100. PubMed ID: 19139040 [Abstract] [Full Text] [Related]
17. Ankyrin-B protein in heart failure: identification of a new component of metazoan cardioprotection. Kashef F, Li J, Wright P, Snyder J, Suliman F, Kilic A, Higgins RS, Anderson ME, Binkley PF, Hund TJ, Mohler PJ. J Biol Chem; 2012 Aug 31; 287(36):30268-81. PubMed ID: 22778271 [Abstract] [Full Text] [Related]
18. Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B. Cunha SR, Bhasin N, Mohler PJ. J Biol Chem; 2007 Feb 16; 282(7):4875-4883. PubMed ID: 17178715 [Abstract] [Full Text] [Related]
19. Mechanisms and Alterations of Cardiac Ion Channels Leading to Disease: Role of Ankyrin-B in Cardiac Function. Sucharski HC, Dudley EK, Keith CBR, El Refaey M, Koenig SN, Mohler PJ. Biomolecules; 2020 Jan 31; 10(2):. PubMed ID: 32023981 [Abstract] [Full Text] [Related]