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Journal Abstract Search

149 related items for PubMed ID: 2186034

  • 1. The importance of loop region residues 40-46 in human dihydrofolate reductase as revealed by site-directed mutagenesis.
    Tan XH, Huang SM, Ratnam M, Thompson PD, Freisheim JH.
    J Biol Chem; 1990 May 15; 265(14):8027-32. PubMed ID: 2186034
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  • 2. Engineering specificity for folate into dihydrofolate reductase from Escherichia coli.
    Posner BA, Li L, Bethell R, Tsuji T, Benkovic SJ.
    Biochemistry; 1996 Feb 06; 35(5):1653-63. PubMed ID: 8634297
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  • 3. Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.
    Thillet J, Absil J, Stone SR, Pictet R.
    J Biol Chem; 1988 Sep 05; 263(25):12500-8. PubMed ID: 3045118
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  • 4. Nonadditivity of mutational effects at the folate binding site of Escherichia coli dihydrofolate reductase.
    Huang Z, Wagner CR, Benkovic SJ.
    Biochemistry; 1994 Sep 27; 33(38):11576-85. PubMed ID: 7918371
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  • 5. Site-directed deletion mutants of a carboxyl-terminal region of human dihydrofolate reductase.
    Bullerjahn AM, Freisheim JH.
    J Biol Chem; 1992 Jan 15; 267(2):864-70. PubMed ID: 1730674
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  • 6. Role of the active-site carboxylate in dihydrofolate reductase: kinetic and spectroscopic studies of the aspartate 26-->asparagine mutant of the Lactobacillus casei enzyme.
    Basran J, Casarotto MG, Barsukov IL, Roberts GC.
    Biochemistry; 1995 Mar 07; 34(9):2872-82. PubMed ID: 7893701
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  • 14. Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.
    Hicks SN, Smiley RD, Hamilton JB, Howell EE.
    Biochemistry; 2003 Sep 16; 42(36):10569-78. PubMed ID: 12962480
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  • 17. Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
    Warren MS, Brown KA, Farnum MF, Howell EE, Kraut J.
    Biochemistry; 1991 Nov 19; 30(46):11092-103. PubMed ID: 1932031
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