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Journal Abstract Search

293 related items for PubMed ID: 21862691

  • 1. High-affinity peroxisome proliferator-activated receptor β/δ-specific ligands with pure antagonistic or inverse agonistic properties.
    Naruhn S, Toth PM, Adhikary T, Kaddatz K, Pape V, Dörr S, Klebe G, Müller-Brüsselbach S, Diederich WE, Müller R.
    Mol Pharmacol; 2011 Nov; 80(5):828-38. PubMed ID: 21862691
    [Abstract] [Full Text] [Related]

  • 2. Design and Synthesis of Highly Active Peroxisome Proliferator-Activated Receptor (PPAR) β/δ Inverse Agonists with Prolonged Cellular Activity.
    Toth PM, Lieber S, Scheer FM, Schumann T, Schober Y, Nockher WA, Adhikary T, Müller-Brüsselbach S, Müller R, Diederich WE.
    ChemMedChem; 2016 Mar 04; 11(5):488-96. PubMed ID: 26864558
    [Abstract] [Full Text] [Related]

  • 3. (Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties.
    Lieber S, Scheer F, Meissner W, Naruhn S, Adhikary T, Müller-Brüsselbach S, Diederich WE, Müller R.
    J Med Chem; 2012 Mar 22; 55(6):2858-68. PubMed ID: 22369181
    [Abstract] [Full Text] [Related]

  • 4. Development of improved PPARβ/δ inhibitors.
    Toth PM, Naruhn S, Pape VF, Dörr SM, Klebe G, Müller R, Diederich WE.
    ChemMedChem; 2012 Jan 02; 7(1):159-70. PubMed ID: 22025402
    [Abstract] [Full Text] [Related]

  • 5. Ligand-mediated regulation of peroxisome proliferator-activated receptor (PPAR) beta/delta: a comparative analysis of PPAR-selective agonists and all-trans retinoic acid.
    Rieck M, Meissner W, Ries S, Müller-Brüsselbach S, Müller R.
    Mol Pharmacol; 2008 Nov 02; 74(5):1269-77. PubMed ID: 18701617
    [Abstract] [Full Text] [Related]

  • 6. Human Endometrial Stromal Cell Differentiation is Stimulated by PPARβ/δ Activation: New Targets for Infertility?
    Yu J, Berga SL, Zou W, Rajakumar A, Man M, Sidell N, Taylor RN.
    J Clin Endocrinol Metab; 2020 Sep 01; 105(9):2983-95. PubMed ID: 32594141
    [Abstract] [Full Text] [Related]

  • 7. 15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist.
    Naruhn S, Meissner W, Adhikary T, Kaddatz K, Klein T, Watzer B, Müller-Brüsselbach S, Müller R.
    Mol Pharmacol; 2010 Feb 01; 77(2):171-84. PubMed ID: 19903832
    [Abstract] [Full Text] [Related]

  • 8. Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.
    Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R.
    Oncogene; 2013 Oct 31; 32(44):5241-52. PubMed ID: 23208498
    [Abstract] [Full Text] [Related]

  • 9. The role of peroxisome proliferator-activated receptor-beta/delta in epidermal growth factor-induced HaCaT cell proliferation.
    Liang P, Jiang B, Yang X, Xiao X, Huang X, Long J, Zhang P, Zhang M, Xiao M, Xie T, Huang X.
    Exp Cell Res; 2008 Oct 15; 314(17):3142-51. PubMed ID: 18625220
    [Abstract] [Full Text] [Related]

  • 10. Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.
    Degenhardt T, Saramäki A, Malinen M, Rieck M, Väisänen S, Huotari A, Herzig KH, Müller R, Carlberg C.
    J Mol Biol; 2007 Sep 14; 372(2):341-55. PubMed ID: 17669420
    [Abstract] [Full Text] [Related]

  • 11. Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions.
    Wagner KD, Wagner N.
    Pharmacol Ther; 2010 Mar 14; 125(3):423-35. PubMed ID: 20026355
    [Abstract] [Full Text] [Related]

  • 12. Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.
    Moulin D, Bianchi A, Boyault S, Sebillaud S, Koufany M, Francois M, Netter P, Jouzeau JY, Terlain B.
    Arthritis Rheum; 2005 Mar 14; 52(3):759-69. PubMed ID: 15751073
    [Abstract] [Full Text] [Related]

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  • 14. Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes.
    Borland MG, Foreman JE, Girroir EE, Zolfaghari R, Sharma AK, Amin S, Gonzalez FJ, Ross AC, Peters JM.
    Mol Pharmacol; 2008 Nov 14; 74(5):1429-42. PubMed ID: 18687807
    [Abstract] [Full Text] [Related]

  • 15. Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) protects against ceramide-induced cellular toxicity in rat brain astrocytes and neurons by activation of ceramide kinase.
    Aleshin S, Reiser G.
    Mol Cell Neurosci; 2014 Mar 14; 59():127-34. PubMed ID: 24513118
    [Abstract] [Full Text] [Related]

  • 16. The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1.
    Barroso E, Eyre E, Palomer X, Vázquez-Carrera M.
    Biochem Pharmacol; 2011 Feb 15; 81(4):534-43. PubMed ID: 21146504
    [Abstract] [Full Text] [Related]

  • 17. Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines.
    He P, Borland MG, Zhu B, Sharma AK, Amin S, El-Bayoumy K, Gonzalez FJ, Peters JM.
    Toxicology; 2008 Dec 05; 254(1-2):112-7. PubMed ID: 18950674
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  • 19. The peroxisome proliferator-activated receptor-β/δ antagonist GSK0660 mitigates retinal cell inflammation and leukostasis.
    Capozzi ME, Savage SR, McCollum GW, Hammer SS, Ramos CJ, Yang R, Bretz CA, Penn JS.
    Exp Eye Res; 2020 Jan 05; 190():107885. PubMed ID: 31758977
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ.
    Kaupang Å, Kase ET, Vo CX, Amundsen M, Vik A, Hansen TV.
    Bioorg Med Chem; 2016 Jan 15; 24(2):247-60. PubMed ID: 26707845
    [Abstract] [Full Text] [Related]

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