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Journal Abstract Search

315 related items for PubMed ID: 21869827

  • 1. The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.
    Edison N, Zuri D, Maniv I, Bornstein B, Lev T, Gottfried Y, Kemeny S, Garcia-Fernandez M, Kagan J, Larisch S.
    Cell Death Differ; 2012 Feb; 19(2):356-68. PubMed ID: 21869827
    [Abstract] [Full Text] [Related]

  • 2. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 3. ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists.
    Bornstein B, Gottfried Y, Edison N, Shekhtman A, Lev T, Glaser F, Larisch S.
    Apoptosis; 2011 Sep 04; 16(9):869-81. PubMed ID: 21695558
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  • 4. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP, Bonavida B.
    Mol Cancer Ther; 2002 Oct 04; 1(12):1051-8. PubMed ID: 12481428
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  • 5. Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
    Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR.
    Cell Death Differ; 2014 Dec 04; 21(12):1862-76. PubMed ID: 25080938
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  • 9. Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation.
    Maas C, Verbrugge I, de Vries E, Savich G, van de Kooij LW, Tait SW, Borst J.
    Cell Death Differ; 2010 Oct 04; 17(10):1613-23. PubMed ID: 20395960
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  • 11. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
    Fu J, Jin Y, Arend LJ.
    J Biol Chem; 2003 Dec 26; 278(52):52660-72. PubMed ID: 14523016
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  • 12. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
    Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T.
    Nat Cell Biol; 2017 Apr 26; 19(4):318-328. PubMed ID: 28288130
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  • 14. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
    Sinicrope FA, Penington RC, Tang XM.
    Clin Cancer Res; 2004 Dec 15; 10(24):8284-92. PubMed ID: 15623604
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  • 15. PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins.
    Li T, Zeng L, Gao W, Cui MZ, Fu X, Xu X.
    Biochim Biophys Acta; 2013 Mar 15; 1832(3):453-74. PubMed ID: 23207240
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  • 16. Inhibition of caspase-8 attenuates neuronal death induced by limbic seizures in a cytochrome c-dependent and Smac/DIABLO-independent way.
    Li T, Lu C, Xia Z, Xiao B, Luo Y.
    Brain Res; 2006 Jul 07; 1098(1):204-11. PubMed ID: 16774749
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  • 17. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
    Adrain C, Creagh EM, Martin SJ.
    EMBO J; 2001 Dec 03; 20(23):6627-36. PubMed ID: 11726499
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  • 18. XIAP activity dictates Apaf-1 dependency for caspase 9 activation.
    Ho AT, Li QH, Okada H, Mak TW, Zacksenhaus E.
    Mol Cell Biol; 2007 Aug 03; 27(16):5673-85. PubMed ID: 17562856
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  • 19. X-linked Inhibitor of Apoptosis Protein promotes the degradation of its antagonist, the pro-apoptotic ARTS protein.
    Bornstein B, Edison N, Gottfried Y, Lev T, Shekhtman A, Gonen H, Rajalingam K, Larisch S.
    Int J Biochem Cell Biol; 2012 Mar 03; 44(3):489-95. PubMed ID: 22185822
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  • 20. Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis.
    Guo F, Nimmanapalli R, Paranawithana S, Wittman S, Griffin D, Bali P, O'Bryan E, Fumero C, Wang HG, Bhalla K.
    Blood; 2002 May 01; 99(9):3419-26. PubMed ID: 11964312
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