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Journal Abstract Search

166 related items for PubMed ID: 21873423

  • 1. Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm.
    Osabe M, Negishi M.
    J Biol Chem; 2011 Oct 14; 286(41):35763-35769. PubMed ID: 21873423
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  • 2. ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53.
    Lee SY, Shin SJ, Kim HS.
    Int J Oncol; 2013 Mar 14; 42(3):1027-35. PubMed ID: 23314357
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  • 3. Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.
    Koike C, Moore R, Negishi M.
    Mol Pharmacol; 2007 May 14; 71(5):1217-21. PubMed ID: 17314319
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  • 4. KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer.
    Yeh JJ, Routh ED, Rubinas T, Peacock J, Martin TD, Shen XJ, Sandler RS, Kim HJ, Keku TO, Der CJ.
    Mol Cancer Ther; 2009 Apr 14; 8(4):834-43. PubMed ID: 19372556
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  • 5. Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover.
    Lim JH, Liu Y, Reineke E, Kao HY.
    J Biol Chem; 2011 Dec 30; 286(52):44403-11. PubMed ID: 22033920
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  • 6. Interaction of the phosphorylated DNA-binding domain in nuclear receptor CAR with its ligand-binding domain regulates CAR activation.
    Shizu R, Min J, Sobhany M, Pedersen LC, Mutoh S, Negishi M.
    J Biol Chem; 2018 Jan 05; 293(1):333-344. PubMed ID: 29133527
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  • 7. ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.
    Sarközi R, Miller B, Pollack V, Feifel E, Mayer G, Sorokin A, Schramek H.
    J Cell Physiol; 2007 Apr 05; 211(1):88-100. PubMed ID: 17131384
    [Abstract] [Full Text] [Related]

  • 8. Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2.
    Kauppinen TM, Chan WY, Suh SW, Wiggins AK, Huang EJ, Swanson RA.
    Proc Natl Acad Sci U S A; 2006 May 02; 103(18):7136-41. PubMed ID: 16627622
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  • 10. Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors.
    Thottassery JV, Sun Y, Westbrook L, Rentz SS, Manuvakhova M, Qu Z, Samuel S, Upshaw R, Cunningham A, Kern FG.
    Cancer Res; 2004 Jul 01; 64(13):4637-47. PubMed ID: 15231676
    [Abstract] [Full Text] [Related]

  • 11. Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.
    Trinko R, Gan G, Gao XB, Sears RM, Guarnieri DJ, DiLeone RJ.
    PLoS One; 2011 Jul 01; 6(11):e27180. PubMed ID: 22076135
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  • 15. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
    Gailhouste L, Ezan F, Bessard A, Frémin C, Rageul J, Langouët S, Baffet G.
    Int J Cancer; 2010 Mar 15; 126(6):1367-77. PubMed ID: 19816936
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  • 17. Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38.
    Chandrakesan P, Ahmed I, Anwar T, Wang Y, Sarkar S, Singh P, Peleg S, Umar S.
    J Biol Chem; 2010 Oct 22; 285(43):33485-33498. PubMed ID: 20710027
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  • 18. Inhibition of MEK/ERK1/2 signalling alters endothelial nitric oxide synthase activity in an agonist-dependent manner.
    Cale JM, Bird IM.
    Biochem J; 2006 Sep 01; 398(2):279-88. PubMed ID: 16716148
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