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182 related items for PubMed ID: 21878633

  • 1. Forced gating motions by a substituted titratable side chain at the bundle crossing of a potassium channel.
    Khurana A, Shao ES, Kim RY, Vilin YY, Huang X, Yang R, Kurata HT.
    J Biol Chem; 2011 Oct 21; 286(42):36686-93. PubMed ID: 21878633
    [Abstract] [Full Text] [Related]

  • 2. Paradoxical activation of an inwardly rectifying potassium channel mutant by spermine: "(b)locking" open the bundle crossing gate.
    Vilin YY, Nunez JJ, Kim RY, Dake GR, Kurata HT.
    Mol Pharmacol; 2013 Oct 21; 84(4):572-81. PubMed ID: 23887925
    [Abstract] [Full Text] [Related]

  • 3. Gating of the ATP-sensitive K+ channel by a pore-lining phenylalanine residue.
    Rojas A, Wu J, Wang R, Jiang C.
    Biochim Biophys Acta; 2007 Jan 21; 1768(1):39-51. PubMed ID: 16970907
    [Abstract] [Full Text] [Related]

  • 4. H bonding at the helix-bundle crossing controls gating in Kir potassium channels.
    Rapedius M, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T.
    Neuron; 2007 Aug 16; 55(4):602-14. PubMed ID: 17698013
    [Abstract] [Full Text] [Related]

  • 5. Role of conserved glycines in pH gating of Kir1.1 (ROMK).
    Sackin H, Nanazashvili M, Palmer LG, Li H.
    Biophys J; 2006 May 15; 90(10):3582-9. PubMed ID: 16533837
    [Abstract] [Full Text] [Related]

  • 6. A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels.
    Zhang RS, Wright JD, Pless SA, Nunez JJ, Kim RY, Li JBW, Yang R, Ahern CA, Kurata HT.
    J Biol Chem; 2015 Jun 19; 290(25):15450-15461. PubMed ID: 25934393
    [Abstract] [Full Text] [Related]

  • 7. Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels.
    Shang L, Tucker SJ.
    Eur Biophys J; 2008 Feb 19; 37(2):165-71. PubMed ID: 17657484
    [Abstract] [Full Text] [Related]

  • 8. Regulation of gating by negative charges in the cytoplasmic pore in the Kir2.1 channel.
    Xie LH, John SA, Ribalet B, Weiss JN.
    J Physiol; 2004 Nov 15; 561(Pt 1):159-68. PubMed ID: 15459242
    [Abstract] [Full Text] [Related]

  • 9. A threonine residue (Thr71) at the intracellular end of the M1 helix plays a critical role in the gating of Kir6.2 channels by intracellular ATP and protons.
    Cui N, Wu J, Xu H, Wang R, Rojas A, Piao H, Mao J, Abdulkadir L, Li L, Jiang C.
    J Membr Biol; 2003 Mar 15; 192(2):111-22. PubMed ID: 12682799
    [Abstract] [Full Text] [Related]

  • 10. Molecular mechanisms of Slo2 K+ channel closure.
    Giese MH, Gardner A, Hansen A, Sanguinetti MC.
    J Physiol; 2017 Apr 01; 595(7):2321-2336. PubMed ID: 27682982
    [Abstract] [Full Text] [Related]

  • 11. Moving the pH gate of the Kir1.1 inward rectifier channel.
    Nanazashvili M, Li H, Palmer LG, Walters DE, Sackin H.
    Channels (Austin); 2007 Apr 01; 1(1):21-8. PubMed ID: 19170254
    [Abstract] [Full Text] [Related]

  • 12. The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels.
    Alagem N, Yesylevskyy S, Reuveny E.
    Biophys J; 2003 Jul 01; 85(1):300-12. PubMed ID: 12829485
    [Abstract] [Full Text] [Related]

  • 13. Regulation of Kir channels by intracellular pH and extracellular K(+): mechanisms of coupling.
    Dahlmann A, Li M, Gao Z, McGarrigle D, Sackin H, Palmer LG.
    J Gen Physiol; 2004 Apr 01; 123(4):441-54. PubMed ID: 15051808
    [Abstract] [Full Text] [Related]

  • 14. Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.
    Kikuta J, Ishii M, Kishimoto K, Kurachi Y.
    Eur J Pharmacol; 2006 Jan 04; 529(1-3):47-54. PubMed ID: 16325804
    [Abstract] [Full Text] [Related]

  • 15. Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing.
    Rapedius M, Paynter JJ, Fowler PW, Shang L, Sansom MS, Tucker SJ, Baukrowitz T.
    Channels (Austin); 2007 Jan 04; 1(5):327-30. PubMed ID: 18690035
    [Abstract] [Full Text] [Related]

  • 16. The ligand-sensitive gate of a potassium channel lies close to the selectivity filter.
    Proks P, Antcliff JF, Ashcroft FM.
    EMBO Rep; 2003 Jan 04; 4(1):70-5. PubMed ID: 12524524
    [Abstract] [Full Text] [Related]

  • 17. Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
    Haider S, Grottesi A, Hall BA, Ashcroft FM, Sansom MS.
    Biophys J; 2005 May 04; 88(5):3310-20. PubMed ID: 15749783
    [Abstract] [Full Text] [Related]

  • 18. Control of KirBac3.1 potassium channel gating at the interface between cytoplasmic domains.
    Zubcevic L, Bavro VN, Muniz JR, Schmidt MR, Wang S, De Zorzi R, Venien-Bryan C, Sansom MS, Nichols CG, Tucker SJ.
    J Biol Chem; 2014 Jan 03; 289(1):143-51. PubMed ID: 24257749
    [Abstract] [Full Text] [Related]

  • 19. Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism.
    Lin YW, Bushman JD, Yan FF, Haidar S, MacMullen C, Ganguly A, Stanley CA, Shyng SL.
    J Biol Chem; 2008 Apr 04; 283(14):9146-56. PubMed ID: 18250167
    [Abstract] [Full Text] [Related]

  • 20. Gating of the kir2.1 channel at the bundle crossing region by intracellular spermine and other cations.
    Huang CW, Kuo CC.
    J Cell Physiol; 2014 Nov 04; 229(11):1703-21. PubMed ID: 24633623
    [Abstract] [Full Text] [Related]

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