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187 related items for PubMed ID: 21878635

  • 1. Group X secreted phospholipase A2 proenzyme is matured by a furin-like proprotein convertase and releases arachidonic acid inside of human HEK293 cells.
    Jemel I, Ii H, Oslund RC, Payré C, Dabert-Gay AS, Douguet D, Chargui K, Scarzello S, Gelb MH, Lambeau G.
    J Biol Chem; 2011 Oct 21; 286(42):36509-21. PubMed ID: 21878635
    [Abstract] [Full Text] [Related]

  • 2. Ectopically expressed pro-group X secretory phospholipase A2 is proteolytically activated in mouse adrenal cells by furin-like proprotein convertases: implications for the regulation of adrenal steroidogenesis.
    Layne JD, Shridas P, Webb NR.
    J Biol Chem; 2015 Mar 20; 290(12):7851-60. PubMed ID: 25623068
    [Abstract] [Full Text] [Related]

  • 3. Effects of the propeptide of group X secreted phospholipase A(2) on substrate specificity and interfacial activity on phospholipid monolayers.
    Point V, Bénarouche A, Jemel I, Parsiegla G, Lambeau G, Carrière F, Cavalier JF.
    Biochimie; 2013 Jan 20; 95(1):51-8. PubMed ID: 22967966
    [Abstract] [Full Text] [Related]

  • 4. Purified group X secretory phospholipase A(2) induced prominent release of arachidonic acid from human myeloid leukemia cells.
    Hanasaki K, Ono T, Saiga A, Morioka Y, Ikeda M, Kawamoto K, Higashino K, Nakano K, Yamada K, Ishizaki J, Arita H.
    J Biol Chem; 1999 Nov 26; 274(48):34203-11. PubMed ID: 10567392
    [Abstract] [Full Text] [Related]

  • 5. Cellular arachidonate-releasing function of novel classes of secretory phospholipase A2s (groups III and XII).
    Murakami M, Masuda S, Shimbara S, Bezzine S, Lazdunski M, Lambeau G, Gelb MH, Matsukura S, Kokubu F, Adachi M, Kudo I.
    J Biol Chem; 2003 Mar 21; 278(12):10657-67. PubMed ID: 12522102
    [Abstract] [Full Text] [Related]

  • 6. A bifunctional role for group IIA secreted phospholipase A2 in human rheumatoid fibroblast-like synoviocyte arachidonic acid metabolism.
    Bryant KJ, Bidgood MJ, Lei PW, Taberner M, Salom C, Kumar V, Lee L, Church WB, Courtenay B, Smart BP, Gelb MH, Cahill MA, Graham GG, McNeil HP, Scott KF.
    J Biol Chem; 2011 Jan 28; 286(4):2492-503. PubMed ID: 21068383
    [Abstract] [Full Text] [Related]

  • 7. Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice.
    Fujioka D, Saito Y, Kobayashi T, Yano T, Tezuka H, Ishimoto Y, Suzuki N, Yokota Y, Nakamura T, Obata JE, Kanazawa M, Kawabata K, Hanasaki K, Kugiyama K.
    Circulation; 2008 Jun 10; 117(23):2977-85. PubMed ID: 18506007
    [Abstract] [Full Text] [Related]

  • 8. Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins.
    Kamitani S, Yamada K, Yamamoto S, Ishimoto Y, Ono T, Saiga A, Hanasaki K.
    Cell Mol Biol Lett; 2012 Sep 10; 17(3):459-78. PubMed ID: 22706677
    [Abstract] [Full Text] [Related]

  • 9. Amplification mechanisms of inflammation: paracrine stimulation of arachidonic acid mobilization by secreted phospholipase A2 is regulated by cytosolic phospholipase A2-derived hydroperoxyeicosatetraenoic acid.
    Balboa MA, Pérez R, Balsinde J.
    J Immunol; 2003 Jul 15; 171(2):989-94. PubMed ID: 12847271
    [Abstract] [Full Text] [Related]

  • 10. Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms.
    Murakami M, Koduri RS, Enomoto A, Shimbara S, Seki M, Yoshihara K, Singer A, Valentin E, Ghomashchi F, Lambeau G, Gelb MH, Kudo I.
    J Biol Chem; 2001 Mar 30; 276(13):10083-96. PubMed ID: 11106649
    [Abstract] [Full Text] [Related]

  • 11. Eosinophil cysteinyl leukotriene synthesis mediated by exogenous secreted phospholipase A2 group X.
    Lai Y, Oslund RC, Bollinger JG, Henderson WR, Santana LF, Altemeier WA, Gelb MH, Hallstrand TS.
    J Biol Chem; 2010 Dec 31; 285(53):41491-500. PubMed ID: 20974857
    [Abstract] [Full Text] [Related]

  • 12. TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.
    Srour N, Lebel A, McMahon S, Fournier I, Fugère M, Day R, Dubois CM.
    FEBS Lett; 2003 Nov 20; 554(3):275-83. PubMed ID: 14623079
    [Abstract] [Full Text] [Related]

  • 13. Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
    Essalmani R, Susan-Resiga D, Guillemot J, Kim W, Sachan V, Awan Z, Chamberland A, Asselin MC, Ly K, Desjardins R, Day R, Prat A, Seidah NG.
    J Biol Chem; 2017 Jun 23; 292(25):10564-10573. PubMed ID: 28468828
    [Abstract] [Full Text] [Related]

  • 14. Different functional aspects of the group II subfamily (Types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation.
    Murakami M, Kambe T, Shimbara S, Higashino K, Hanasaki K, Arita H, Horiguchi M, Arita M, Arai H, Inoue K, Kudo I.
    J Biol Chem; 1999 Oct 29; 274(44):31435-44. PubMed ID: 10531345
    [Abstract] [Full Text] [Related]

  • 15. Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.
    Tian S, Jianhua W.
    Int J Biol Sci; 2010 Feb 03; 6(1):89-95. PubMed ID: 20151049
    [Abstract] [Full Text] [Related]

  • 16. Blockade of human group X secreted phospholipase A2 (GX-sPLA2)-induced airway inflammation and hyperresponsiveness in a mouse asthma model by a selective GX-sPLA2 inhibitor.
    Henderson WR, Oslund RC, Bollinger JG, Ye X, Tien YT, Xue J, Gelb MH.
    J Biol Chem; 2011 Aug 12; 286(32):28049-55. PubMed ID: 21652694
    [Abstract] [Full Text] [Related]

  • 17. Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases.
    Wüthrich M, Creemers JW, van de Ven WJ, Sterchi EE.
    Biochim Biophys Acta; 1996 May 28; 1311(3):199-203. PubMed ID: 8664347
    [Abstract] [Full Text] [Related]

  • 18. Proprotein convertases process and thereby inactivate formylglycine-generating enzyme.
    Ennemann EC, Radhakrishnan K, Mariappan M, Wachs M, Pringle TH, Schmidt B, Dierks T.
    J Biol Chem; 2013 Feb 22; 288(8):5828-39. PubMed ID: 23288839
    [Abstract] [Full Text] [Related]

  • 19. Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor.
    Morioka Y, Saiga A, Yokota Y, Suzuki N, Ikeda M, Ono T, Nakano K, Fujii N, Ishizaki J, Arita H, Hanasaki K.
    Arch Biochem Biophys; 2000 Sep 01; 381(1):31-42. PubMed ID: 11019817
    [Abstract] [Full Text] [Related]

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