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Journal Abstract Search

217 related items for PubMed ID: 21878661

  • 21. The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.
    Sun J, Sun Q, Brown MF, Dudgeon C, Chandler J, Xu X, Shu Y, Zhang L, Yu J.
    PLoS One; 2012; 7(8):e43158. PubMed ID: 22912816
    [Abstract] [Full Text] [Related]

  • 22. Baicalin induces apoptosis in leukemia HL-60/ADR cells via possible down-regulation of the PI3K/Akt signaling pathway.
    Zheng J, Hu JD, Chen YY, Chen BY, Huang Y, Zheng ZH, Liu TB.
    Asian Pac J Cancer Prev; 2012; 13(4):1119-24. PubMed ID: 22799292
    [Abstract] [Full Text] [Related]

  • 23. The dual mTORC1 and mTORC2 inhibitor PP242 shows strong antitumor activity in a pheochromocytoma PC12 cell tumor model.
    Zhang X, Wang X, Qin L, Xu T, Zhu Z, Zhong S, Zhang M, Shen Z.
    Urology; 2015 Jan; 85(1):273.e1-7. PubMed ID: 25440763
    [Abstract] [Full Text] [Related]

  • 24. Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling.
    Xu X, Jiang J, Yao L, Ji B.
    Med Sci Monit; 2018 Nov 11; 24():8064-8073. PubMed ID: 30415267
    [Abstract] [Full Text] [Related]

  • 25. Systematic combination screening reveals synergism between rapamycin and sunitinib against human lung cancer.
    Li X, Tong LJ, Ding J, Meng LH.
    Cancer Lett; 2014 Jan 01; 342(1):159-66. PubMed ID: 24018642
    [Abstract] [Full Text] [Related]

  • 26. Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1.
    Di Desidero T, Fioravanti A, Orlandi P, Canu B, Giannini R, Borrelli N, Man S, Xu P, Fontanini G, Basolo F, Kerbel RS, Francia G, Danesi R, Bocci G.
    J Clin Endocrinol Metab; 2013 Sep 01; 98(9):E1465-73. PubMed ID: 23969186
    [Abstract] [Full Text] [Related]

  • 27. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.
    Kim SW, Kim SM, Bae H, Nam D, Lee JH, Lee SG, Shim BS, Kim SH, Ahn KS, Choi SH, Sethi G, Ahn KS.
    Prostate; 2013 Feb 15; 73(3):296-305. PubMed ID: 22887478
    [Abstract] [Full Text] [Related]

  • 28. Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma.
    Huang D, Ding Y, Li Y, Luo WM, Zhang ZF, Snider J, Vandenbeldt K, Qian CN, Teh BT.
    Cancer Res; 2010 Feb 01; 70(3):1053-62. PubMed ID: 20103629
    [Abstract] [Full Text] [Related]

  • 29. β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation.
    Park KR, Nam D, Yun HM, Lee SG, Jang HJ, Sethi G, Cho SK, Ahn KS.
    Cancer Lett; 2011 Dec 22; 312(2):178-88. PubMed ID: 21924548
    [Abstract] [Full Text] [Related]

  • 30. Modulation of Akt/mTOR signaling overcomes sunitinib resistance in renal and prostate cancer cells.
    Makhov PB, Golovine K, Kutikov A, Teper E, Canter DJ, Simhan J, Uzzo RG, Kolenko VM.
    Mol Cancer Ther; 2012 Jul 22; 11(7):1510-7. PubMed ID: 22532600
    [Abstract] [Full Text] [Related]

  • 31. Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas.
    Cassol CA, Winer D, Liu W, Guo M, Ezzat S, Asa SL.
    Mod Pathol; 2014 Aug 22; 27(8):1050-62. PubMed ID: 24390213
    [Abstract] [Full Text] [Related]

  • 32. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ.
    Cancer Res; 2006 Jul 01; 66(13):6589-97. PubMed ID: 16818631
    [Abstract] [Full Text] [Related]

  • 33. SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells.
    Mohan N, Karmakar S, Banik NL, Ray SK.
    Neurochem Res; 2011 Aug 01; 36(8):1383-96. PubMed ID: 21472456
    [Abstract] [Full Text] [Related]

  • 34. Hyperglycemia-induced Bcl-2/Bax-mediated apoptosis of Schwann cells via mTORC1/S6K1 inhibition in diabetic peripheral neuropathy.
    Zhu L, Hao J, Cheng M, Zhang C, Huo C, Liu Y, Du W, Zhang X.
    Exp Cell Res; 2018 Jun 15; 367(2):186-195. PubMed ID: 29621478
    [Abstract] [Full Text] [Related]

  • 35. Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib.
    Serova M, de Gramont A, Tijeras-Raballand A, Dos Santos C, Riveiro ME, Slimane K, Faivre S, Raymond E.
    Cancer Chemother Pharmacol; 2013 May 15; 71(5):1297-307. PubMed ID: 23479136
    [Abstract] [Full Text] [Related]

  • 36. Resveratrol induces apoptosis and autophagy in T-cell acute lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating p38-MAPK.
    Ge J, Liu Y, Li Q, Guo X, Gu L, Ma ZG, Zhu YP.
    Biomed Environ Sci; 2013 Nov 15; 26(11):902-11. PubMed ID: 24331535
    [Abstract] [Full Text] [Related]

  • 37. Sunitinib inhibits tumor vascularity and growth but does not affect Akt and ERK phosphorylation in xenograft tumors.
    Voce P, D'Agostino M, Moretti S, Sponziello M, Rhoden K, Calcinaro F, Tamburrano G, Tallini G, Puxeddu E, Filetti S, Russo D, Durante C.
    Oncol Rep; 2011 Nov 15; 26(5):1075-80. PubMed ID: 21850379
    [Abstract] [Full Text] [Related]

  • 38. The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries.
    Abdel-Aziz AK, Mantawy EM, Said RS, Helwa R.
    Exp Neurol; 2016 Sep 15; 283(Pt A):129-41. PubMed ID: 27288242
    [Abstract] [Full Text] [Related]

  • 39. Sublytic C5b-9-stimulated Schwann cell survival through PI 3-kinase-mediated phosphorylation of BAD.
    Hila S, Soane L, Koski CL.
    Glia; 2001 Oct 15; 36(1):58-67. PubMed ID: 11571784
    [Abstract] [Full Text] [Related]

  • 40. Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways.
    Jiang JH, Pi J, Jin H, Cai JY.
    J Cell Biochem; 2019 Mar 15; 120(3):3736-3746. PubMed ID: 30229997
    [Abstract] [Full Text] [Related]

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