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Journal Abstract Search


215 related items for PubMed ID: 21885830

  • 1. p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility.
    Momotani K, Artamonov MV, Utepbergenov D, Derewenda U, Derewenda ZS, Somlyo AV.
    Circ Res; 2011 Oct 14; 109(9):993-1002. PubMed ID: 21885830
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  • 2. p63RhoGEF: a new switch for G(q)-mediated activation of smooth muscle.
    Momotani K, Somlyo AV.
    Trends Cardiovasc Med; 2012 Jul 14; 22(5):122-7. PubMed ID: 22902181
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  • 4. The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.
    Lutz S, Freichel-Blomquist A, Yang Y, Rümenapp U, Jakobs KH, Schmidt M, Wieland T.
    J Biol Chem; 2005 Mar 25; 280(12):11134-9. PubMed ID: 15632174
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  • 6. Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.
    Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J.
    J Biol Chem; 2007 Oct 05; 282(40):29201-10. PubMed ID: 17606614
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  • 7. Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells.
    Aittaleb M, Nishimura A, Linder ME, Tesmer JJ.
    J Biol Chem; 2011 Sep 30; 286(39):34448-56. PubMed ID: 21832057
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  • 8. Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.
    Gohla A, Schultz G, Offermanns S.
    Circ Res; 2000 Aug 04; 87(3):221-7. PubMed ID: 10926873
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  • 9. Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle.
    Sauzeau V, Le Jeune H, Cario-Toumaniantz C, Smolenski A, Lohmann SM, Bertoglio J, Chardin P, Pacaud P, Loirand G.
    J Biol Chem; 2000 Jul 14; 275(28):21722-9. PubMed ID: 10783386
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  • 11. Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.
    Shankaranarayanan A, Boguth CA, Lutz S, Vettel C, Uhlemann F, Aittaleb M, Wieland T, Tesmer JJ.
    Cell Signal; 2010 Jul 14; 22(7):1114-23. PubMed ID: 20214977
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  • 12. Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis.
    Siegert P, Schmidt G, Papatheodorou P, Wieland T, Aktories K, Orth JH.
    PLoS Pathog; 2013 Jul 14; 9(5):e1003385. PubMed ID: 23696743
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  • 13. Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans.
    Williams SL, Lutz S, Charlie NK, Vettel C, Ailion M, Coco C, Tesmer JJ, Jorgensen EM, Wieland T, Miller KG.
    Genes Dev; 2007 Nov 01; 21(21):2731-46. PubMed ID: 17942708
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  • 14. p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
    Wuertz CM, Lorincz A, Vettel C, Thomas MA, Wieland T, Lutz S.
    FASEB J; 2010 Dec 01; 24(12):4865-76. PubMed ID: 20739613
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  • 15. Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.
    Lutz S, Shankaranarayanan A, Coco C, Ridilla M, Nance MR, Vettel C, Baltus D, Evelyn CR, Neubig RR, Wieland T, Tesmer JJ.
    Science; 2007 Dec 21; 318(5858):1923-7. PubMed ID: 18096806
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  • 16. The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.
    Siderovski DP, Willard FS.
    Int J Biol Sci; 2005 Dec 21; 1(2):51-66. PubMed ID: 15951850
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  • 18. Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle.
    Gong MC, Iizuka K, Nixon G, Browne JP, Hall A, Eccleston JF, Sugai M, Kobayashi S, Somlyo AV, Somlyo AP.
    Proc Natl Acad Sci U S A; 1996 Feb 06; 93(3):1340-5. PubMed ID: 8577766
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  • 19. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
    Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M, Takata S, Kaneko S, Takuwa Y.
    Cardiovasc Res; 2008 Sep 01; 79(4):689-97. PubMed ID: 18480127
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  • 20. LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways.
    Pfreimer M, Vatter P, Langer T, Wieland T, Gierschik P, Moepps B.
    Cell Signal; 2012 Mar 01; 24(3):652-63. PubMed ID: 22100544
    [Abstract] [Full Text] [Related]


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