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Journal Abstract Search

338 related items for PubMed ID: 21896647

  • 1. Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin.
    Lajoie P, Snapp EL.
    J Cell Sci; 2011 Oct 01; 124(Pt 19):3332-43. PubMed ID: 21896647
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  • 2. BiP availability distinguishes states of homeostasis and stress in the endoplasmic reticulum of living cells.
    Lai CW, Aronson DE, Snapp EL.
    Mol Biol Cell; 2010 Jun 15; 21(12):1909-21. PubMed ID: 20410136
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  • 3. GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins.
    Jiang Y, Lv H, Liao M, Xu X, Huang S, Tan H, Peng T, Zhang Y, Li H.
    Neurosci Lett; 2012 May 16; 516(2):182-7. PubMed ID: 22490889
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  • 4. Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.
    Reijonen S, Putkonen N, Nørremølle A, Lindholm D, Korhonen L.
    Exp Cell Res; 2008 Mar 10; 314(5):950-60. PubMed ID: 18255062
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  • 5. Pridopidine reduces mutant huntingtin-induced endoplasmic reticulum stress by modulation of the Sigma-1 receptor.
    Shenkman M, Geva M, Gershoni-Emek N, Hayden MR, Lederkremer GZ.
    J Neurochem; 2021 Jul 10; 158(2):467-481. PubMed ID: 33871049
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  • 6. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.
    Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW, Lee ST, Kim M, Ryu H, Jung YK.
    Hum Mol Genet; 2012 Jan 01; 21(1):101-14. PubMed ID: 21954231
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  • 10. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
    Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW.
    J Neurosci; 2008 Jun 11; 28(24):6182-95. PubMed ID: 18550760
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  • 11. Rosiglitazone activation of PPARγ-dependent signaling is neuroprotective in mutant huntingtin expressing cells.
    Chiang MC, Cheng YC, Nicol CJ, Lin KH, Yen CH, Chen SJ, Huang RN.
    Exp Cell Res; 2015 Nov 01; 338(2):183-93. PubMed ID: 26362846
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  • 17. ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin.
    Leitman J, Barak B, Benyair R, Shenkman M, Ashery U, Hartl FU, Lederkremer GZ.
    PLoS One; 2014 Nov 01; 9(3):e90803. PubMed ID: 24594939
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  • 18. AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease.
    Zuleta A, Vidal RL, Armentano D, Parsons G, Hetz C.
    Biochem Biophys Res Commun; 2012 Apr 13; 420(3):558-63. PubMed ID: 22445760
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  • 19. A screen for enhancers of clearance identifies huntingtin as a heat shock protein 90 (Hsp90) client protein.
    Baldo B, Weiss A, Parker CN, Bibel M, Paganetti P, Kaupmann K.
    J Biol Chem; 2012 Jan 06; 287(2):1406-14. PubMed ID: 22123826
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  • 20. Glutathione redox cycle dysregulation in Huntington's disease knock-in striatal cells.
    Ribeiro M, Rosenstock TR, Cunha-Oliveira T, Ferreira IL, Oliveira CR, Rego AC.
    Free Radic Biol Med; 2012 Nov 15; 53(10):1857-67. PubMed ID: 22982598
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