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Journal Abstract Search

766 related items for PubMed ID: 21900357

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  • 4. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
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  • 5. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
    Ochalek A, Mihalik B, Avci HX, Chandrasekaran A, Téglási A, Bock I, Giudice ML, Táncos Z, Molnár K, László L, Nielsen JE, Holst B, Freude K, Hyttel P, Kobolák J, Dinnyés A.
    Alzheimers Res Ther; 2017 Dec 01; 9(1):90. PubMed ID: 29191219
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  • 6. Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.
    Hahn S, Brüning T, Ness J, Czirr E, Baches S, Gijsen H, Korth C, Pietrzik CU, Bulic B, Weggen S.
    J Neurochem; 2011 Feb 01; 116(3):385-95. PubMed ID: 21091478
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  • 8. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K, Tomioka M, Kremmer E, Haass C, Steiner H.
    Neurobiol Dis; 2007 Jul 01; 27(1):102-7. PubMed ID: 17560791
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  • 9. Pathological manifestation of the induced pluripotent stem cell-derived cortical neurons from an early-onset Alzheimer's disease patient carrying a presenilin-1 mutation (S170F).
    Li L, Kim HJ, Roh JH, Kim M, Koh W, Kim Y, Heo H, Chung J, Nakanishi M, Yoon T, Hong CP, Seo SW, Na DL, Song J.
    Cell Prolif; 2020 Apr 01; 53(4):e12798. PubMed ID: 32216003
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  • 10. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.
    Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS.
    Nature; 2012 Jan 25; 482(7384):216-20. PubMed ID: 22278060
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  • 12. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
    Sevalle J, Ayral E, Hernandez JF, Martinez J, Checler F.
    J Neurochem; 2009 Jul 25; 110(1):275-83. PubMed ID: 19457123
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  • 13. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
    Marambaud P, Alves da Costa C, Ancolio K, Checler F.
    Biochem Biophys Res Commun; 1998 Nov 09; 252(1):134-8. PubMed ID: 9813158
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  • 15. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M, Skobeleva K, Glushankova L, Kaznacheyeva E.
    J Neurochem; 2016 Mar 09; 136(5):1085-95. PubMed ID: 26678016
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  • 16. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
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  • 17. Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse.
    Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP.
    J Neurosci Res; 2008 May 15; 86(7):1615-25. PubMed ID: 18189321
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  • 18. Flexible and Accurate Substrate Processing with Distinct Presenilin/γ-Secretases in Human Cortical Neurons.
    Watanabe H, Imaizumi K, Cai T, Zhou Z, Tomita T, Okano H.
    eNeuro; 2021 May 15; 8(2):. PubMed ID: 33608391
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  • 19. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 15; 92(2):294-301. PubMed ID: 15663477
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  • 20. Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells.
    Armijo E, Gonzalez C, Shahnawaz M, Flores A, Davis B, Soto C.
    Neurosci Lett; 2017 Feb 03; 639():74-81. PubMed ID: 28034781
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