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284 related items for PubMed ID: 21903925

  • 1. Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death.
    Jain P, Luo ZQ, Blanke SR.
    Proc Natl Acad Sci U S A; 2011 Sep 20; 108(38):16032-7. PubMed ID: 21903925
    [Abstract] [Full Text] [Related]

  • 2. Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.
    Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.
    J Biol Chem; 2006 Apr 21; 281(16):11250-9. PubMed ID: 16436379
    [Abstract] [Full Text] [Related]

  • 3. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 4. Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis.
    Brooks C, Cho SG, Wang CY, Yang T, Dong Z.
    Am J Physiol Cell Physiol; 2011 Mar 04; 300(3):C447-55. PubMed ID: 21160028
    [Abstract] [Full Text] [Related]

  • 5. Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death.
    Wasiak S, Zunino R, McBride HM.
    J Cell Biol; 2007 May 07; 177(3):439-50. PubMed ID: 17470634
    [Abstract] [Full Text] [Related]

  • 6. Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
    Parone PA, James DI, Da Cruz S, Mattenberger Y, Donzé O, Barja F, Martinou JC.
    Mol Cell Biol; 2006 Oct 07; 26(20):7397-408. PubMed ID: 17015472
    [Abstract] [Full Text] [Related]

  • 7. Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.
    Xian H, Liou YC.
    Autophagy; 2019 Dec 07; 15(12):2107-2125. PubMed ID: 30894073
    [Abstract] [Full Text] [Related]

  • 8. Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms.
    Chatre L, Fernandes J, Michel V, Fiette L, Avé P, Arena G, Jain U, Haas R, Wang TC, Ricchetti M, Touati E.
    Sci Rep; 2017 Nov 21; 7(1):15901. PubMed ID: 29162845
    [Abstract] [Full Text] [Related]

  • 9. N-terminal phosphorylation of protein phosphatase 2A/Bβ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival.
    Merrill RA, Slupe AM, Strack S.
    FEBS J; 2013 Jan 21; 280(2):662-73. PubMed ID: 22583914
    [Abstract] [Full Text] [Related]

  • 10. 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells.
    Gomez-Lazaro M, Bonekamp NA, Galindo MF, Jordán J, Schrader M.
    Free Radic Biol Med; 2008 Jun 01; 44(11):1960-9. PubMed ID: 18395527
    [Abstract] [Full Text] [Related]

  • 11. Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA.
    Calore F, Genisset C, Casellato A, Rossato M, Codolo G, Esposti MD, Scorrano L, de Bernard M.
    Cell Death Differ; 2010 Nov 01; 17(11):1707-16. PubMed ID: 20431599
    [Abstract] [Full Text] [Related]

  • 12. Mitochondrial chaperone DnaJA3 induces Drp1-dependent mitochondrial fragmentation.
    Elwi AN, Lee B, Meijndert HC, Braun JE, Kim SW.
    Int J Biochem Cell Biol; 2012 Aug 01; 44(8):1366-76. PubMed ID: 22595283
    [Abstract] [Full Text] [Related]

  • 13. Indomethacin impairs mitochondrial dynamics by activating the PKCζ-p38-DRP1 pathway and inducing apoptosis in gastric cancer and normal mucosal cells.
    Mazumder S, De R, Debsharma S, Bindu S, Maity P, Sarkar S, Saha SJ, Siddiqui AA, Banerjee C, Nag S, Saha D, Pramanik S, Mitra K, Bandyopadhyay U.
    J Biol Chem; 2019 May 17; 294(20):8238-8258. PubMed ID: 30940726
    [Abstract] [Full Text] [Related]

  • 14. Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation.
    Willhite DC, Cover TL, Blanke SR.
    J Biol Chem; 2003 Nov 28; 278(48):48204-9. PubMed ID: 13129933
    [Abstract] [Full Text] [Related]

  • 15. Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis.
    Estaquier J, Arnoult D.
    Cell Death Differ; 2007 Jun 28; 14(6):1086-94. PubMed ID: 17332775
    [Abstract] [Full Text] [Related]

  • 16. Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy.
    Wu S, Zhou F, Zhang Z, Xing D.
    J Cell Physiol; 2011 Feb 28; 226(2):530-41. PubMed ID: 20683914
    [Abstract] [Full Text] [Related]

  • 17. Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.
    Zhao J, Liu T, Jin S, Wang X, Qu M, Uhlén P, Tomilin N, Shupliakov O, Lendahl U, Nistér M.
    EMBO J; 2011 Jun 24; 30(14):2762-78. PubMed ID: 21701560
    [Abstract] [Full Text] [Related]

  • 18. A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.
    Tanaka A, Youle RJ.
    Mol Cell; 2008 Feb 29; 29(4):409-10. PubMed ID: 18313377
    [Abstract] [Full Text] [Related]

  • 19. Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1.
    Kim IJ, Lee J, Oh SJ, Yoon MS, Jang SS, Holland RL, Reno ML, Hamad MN, Maeda T, Chung HJ, Chen J, Blanke SR.
    Cell Host Microbe; 2018 May 09; 23(5):583-593.e8. PubMed ID: 29746831
    [Abstract] [Full Text] [Related]

  • 20. Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis.
    Wang P, Wang P, Liu B, Zhao J, Pang Q, Agrawal SG, Jia L, Liu FT.
    Oncotarget; 2015 Sep 08; 6(26):22598-612. PubMed ID: 26093086
    [Abstract] [Full Text] [Related]

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