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275 related items for PubMed ID: 21911753

  • 1. Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.
    Syed I, Kyathanahalli CN, Jayaram B, Govind S, Rhodes CJ, Kowluru RA, Kowluru A.
    Diabetes; 2011 Nov; 60(11):2843-52. PubMed ID: 21911753
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  • 2. Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.
    Syed I, Kyathanahalli CN, Kowluru A.
    Am J Physiol Regul Integr Comp Physiol; 2011 Mar; 300(3):R756-62. PubMed ID: 21228337
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  • 7. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).
    Sidarala V, Veluthakal R, Syeda K, Vlaar C, Newsholme P, Kowluru A.
    Biochem Pharmacol; 2015 Jun 15; 95(4):301-10. PubMed ID: 25881746
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  • 8. Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways.
    Bruder-Nascimento T, Callera GE, Montezano AC, He Y, Antunes TT, Nguyen Dinh Cat A, Tostes RC, Touyz RM.
    Clin Sci (Lond); 2015 Apr 15; 128(7):411-23. PubMed ID: 25358739
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  • 9. Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell.
    Jayaram B, Kowluru A.
    Cell Physiol Biochem; 2012 Apr 15; 30(6):1351-62. PubMed ID: 23095975
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  • 10. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia.
    Shen E, Li Y, Li Y, Shan L, Zhu H, Feng Q, Arnold JM, Peng T.
    Diabetes; 2009 Oct 15; 58(10):2386-95. PubMed ID: 19592621
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  • 11. TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.
    Jin S, Ray RM, Johnson LR.
    Am J Physiol Gastrointest Liver Physiol; 2008 Apr 15; 294(4):G928-37. PubMed ID: 18218673
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  • 12. NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model.
    Veluthakal R, Sidarala V, Kowluru A.
    Cell Physiol Biochem; 2016 Apr 15; 39(2):760-7. PubMed ID: 27467102
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  • 13. Resveratrol regulates blood pressure by enhancing AMPK signaling to downregulate a Rac1-derived NADPH oxidase in the central nervous system.
    Yeh TC, Shin CS, Chen HH, Lai CC, Sun GC, Tseng CJ, Cheng PW.
    J Appl Physiol (1985); 2018 Jul 01; 125(1):40-48. PubMed ID: 29494287
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  • 14. High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol.
    Zhang L, Pang S, Deng B, Qian L, Chen J, Zou J, Zheng J, Yang L, Zhang C, Chen X, Liu Z, Le Y.
    Int J Biochem Cell Biol; 2012 Apr 01; 44(4):629-38. PubMed ID: 22245600
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  • 15. Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.
    Xu C, Wang X, Gu C, Zhang H, Zhang R, Dong X, Liu C, Hu X, Ji X, Huang S, Chen L.
    J Neurochem; 2017 Apr 01; 141(1):48-62. PubMed ID: 28129433
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  • 16. Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation.
    Kuo WW, Wang WJ, Tsai CY, Way CL, Hsu HH, Chen LM.
    Int J Cardiol; 2013 Sep 20; 168(1):270-80. PubMed ID: 23158927
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  • 17. Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidase-dependent generation of reactive oxygen species.
    Kim JY, Yu SJ, Oh HJ, Lee JY, Kim Y, Sohn J.
    Apoptosis; 2011 Apr 20; 16(4):347-58. PubMed ID: 21190085
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  • 18. Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches.
    Kowluru A.
    Biochem Pharmacol; 2011 Apr 15; 81(8):965-75. PubMed ID: 21300027
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  • 19. EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.
    Carmona-Cuenca I, Herrera B, Ventura JJ, Roncero C, Fernández M, Fabregat I.
    J Cell Physiol; 2006 May 15; 207(2):322-30. PubMed ID: 16331683
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