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Journal Abstract Search

211 related items for PubMed ID: 21914835

  • 1. Involvement of different human glutathione transferase isoforms in the glutathione conjugation of reactive metabolites of troglitazone.
    Okada R, Maeda K, Nishiyama T, Aoyama S, Tozuka Z, Hiratsuka A, Ikeda T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Dec; 39(12):2290-7. PubMed ID: 21914835
    [Abstract] [Full Text] [Related]

  • 2. In vitro investigation of the glutathione transferase M1 and T1 null genotypes as risk factors for troglitazone-induced liver injury.
    Usui T, Hashizume T, Katsumata T, Yokoi T, Komuro S.
    Drug Metab Dispos; 2011 Jul; 39(7):1303-10. PubMed ID: 21511944
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  • 3. Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.
    Kassahun K, Pearson PG, Tang W, McIntosh I, Leung K, Elmore C, Dean D, Wang R, Doss G, Baillie TA.
    Chem Res Toxicol; 2001 Jan; 14(1):62-70. PubMed ID: 11170509
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  • 4. Thiazolidinedione bioactivation: a comparison of the bioactivation potentials of troglitazone, rosiglitazone, and pioglitazone using stable isotope-labeled analogues and liquid chromatography tandem mass spectrometry.
    Alvarez-Sanchez R, Montavon F, Hartung T, Pähler A.
    Chem Res Toxicol; 2006 Aug; 19(8):1106-16. PubMed ID: 16918252
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  • 5. Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved.
    He K, Talaat RE, Pool WF, Reily MD, Reed JE, Bridges AJ, Woolf TF.
    Drug Metab Dispos; 2004 Jun; 32(6):639-46. PubMed ID: 15155556
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  • 6. Role of human glutathione S-transferases in the inactivation of reactive metabolites of clozapine.
    Dragovic S, Boerma JS, van Bergen L, Vermeulen NP, Commandeur JN.
    Chem Res Toxicol; 2010 Sep 20; 23(9):1467-76. PubMed ID: 20849150
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  • 8. Glutathione S-transferase conjugation of organophosphorus pesticides yields S-phospho-, S-aryl-, and S-alkylglutathione derivatives.
    Fujioka K, Casida JE.
    Chem Res Toxicol; 2007 Aug 20; 20(8):1211-7. PubMed ID: 17645302
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  • 12. Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Dirven HA, van Ommen B, van Bladeren PJ.
    Cancer Res; 1994 Dec 01; 54(23):6215-20. PubMed ID: 7954469
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  • 13. Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation.
    Dekker SJ, Zhang Y, Vos JC, Vermeulen NP, Commandeur JN.
    Chem Res Toxicol; 2016 Dec 19; 29(12):2136-2144. PubMed ID: 27989146
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  • 14. Identification of glutathione conjugates of troglitazone in human hepatocytes.
    Prabhu S, Fackett A, Lloyd S, McClellan HA, Terrell CM, Silber PM, Li AP.
    Chem Biol Interact; 2002 Nov 10; 142(1-2):83-97. PubMed ID: 12399157
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  • 16. Dansyl glutathione as a trapping agent for the quantitative estimation and identification of reactive metabolites.
    Gan J, Harper TW, Hsueh MM, Qu Q, Humphreys WG.
    Chem Res Toxicol; 2005 May 10; 18(5):896-903. PubMed ID: 15892584
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  • 17. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
    Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL.
    Chem Res Toxicol; 1998 Jul 10; 11(7):758-65. PubMed ID: 9671538
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  • 18. Application of exogenous mixture of glutathione and stable isotope labeled glutathione for trapping reactive metabolites in cryopreserved human hepatocytes. Detection of the glutathione conjugates using high resolution accurate mass spectrometry.
    Mezine I, Bode C, Raughley B, Bhoopathy S, Roberts KJ, Owen AJ, Hidalgo IJ.
    Chem Biol Interact; 2013 Aug 25; 204(3):173-84. PubMed ID: 23747843
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  • 19. Metabolism of troglitazone in hepatocytes isolated from experimentally induced diabetic rats.
    Meechan AJ, Henderson C, Bates CD, Grant MH, Tettey JN.
    J Pharm Pharmacol; 2006 Oct 25; 58(10):1359-65. PubMed ID: 17034659
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