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498 related items for PubMed ID: 21916504

  • 1. Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway.
    Hsieh YC, Rao YK, Whang-Peng J, Huang CY, Shyue SK, Hsu SL, Tzeng YM.
    J Agric Food Chem; 2011 Oct 26; 59(20):10943-54. PubMed ID: 21916504
    [Abstract] [Full Text] [Related]

  • 2. Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway.
    Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL, Tzeng YM.
    Chem Res Toxicol; 2010 Jul 19; 23(7):1256-67. PubMed ID: 20557081
    [Abstract] [Full Text] [Related]

  • 3. Supercritical carbon dioxide extraction of aromatic turmerone from Curcuma longa Linn. induces apoptosis through reactive oxygen species-triggered intrinsic and extrinsic pathways in human hepatocellular carcinoma HepG2 cells.
    Cheng SB, Wu LC, Hsieh YC, Wu CH, Chan YJ, Chang LH, Chang CM, Hsu SL, Teng CL, Wu CC.
    J Agric Food Chem; 2012 Sep 26; 60(38):9620-30. PubMed ID: 22946656
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways.
    Kang N, Zhang JH, Qiu F, Tashiro S, Onodera S, Ikejima T.
    Cancer Lett; 2010 Aug 28; 294(2):147-58. PubMed ID: 20202741
    [Abstract] [Full Text] [Related]

  • 5. Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms.
    Chen CY, Liu TZ, Chen CH, Wu CC, Cheng JT, Yiin SJ, Shih MK, Wu MJ, Chern CL.
    Food Chem Toxicol; 2007 Jul 28; 45(7):1268-76. PubMed ID: 17321026
    [Abstract] [Full Text] [Related]

  • 6. Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.
    Chiang JH, Yang JS, Ma CY, Yang MD, Huang HY, Hsia TC, Kuo HM, Wu PP, Lee TH, Chung JG.
    Chem Res Toxicol; 2011 Jan 14; 24(1):20-9. PubMed ID: 21126053
    [Abstract] [Full Text] [Related]

  • 7. A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation.
    Oh SH, Lim SC.
    Toxicol Appl Pharmacol; 2006 May 01; 212(3):212-23. PubMed ID: 16169029
    [Abstract] [Full Text] [Related]

  • 8. Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.
    Caja L, Sancho P, Bertran E, Iglesias-Serret D, Gil J, Fabregat I.
    Cancer Res; 2009 Oct 01; 69(19):7595-602. PubMed ID: 19773433
    [Abstract] [Full Text] [Related]

  • 9. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM, Choi YJ, Han Y, Yun YS, Hong SH.
    Toxicol Appl Pharmacol; 2009 Aug 15; 239(1):87-97. PubMed ID: 19481559
    [Abstract] [Full Text] [Related]

  • 10. Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells.
    Raza H, John A, Benedict S.
    Eur J Pharmacol; 2011 Oct 01; 668(1-2):15-24. PubMed ID: 21722632
    [Abstract] [Full Text] [Related]

  • 11. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 12. Involvement of NF-kappaB activation in the apoptosis induced by extracellular adenosine in human hepatocellular carcinoma HepG2 cells.
    Wu LF, Li GP, Su JD, Pu ZJ, Feng JL, Ye YQ, Wei BL.
    Biochem Cell Biol; 2010 Aug 22; 88(4):705-14. PubMed ID: 20651843
    [Abstract] [Full Text] [Related]

  • 13. MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway.
    Ying M, Tu C, Ying H, Hu Y, He Q, Yang B.
    J Pharmacol Exp Ther; 2008 Jun 22; 325(3):758-65. PubMed ID: 18323457
    [Abstract] [Full Text] [Related]

  • 14. Gypenosides induce apoptosis in human hepatoma Huh-7 cells through a calcium/reactive oxygen species-dependent mitochondrial pathway.
    Wang QF, Chiang CW, Wu CC, Cheng CC, Hsieh SJ, Chen JC, Hsieh YC, Hsu SL.
    Planta Med; 2007 Jun 22; 73(6):535-44. PubMed ID: 17520521
    [Abstract] [Full Text] [Related]

  • 15. NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway.
    Liu L, Fu J, Li T, Cui R, Ling J, Yu X, Ji H, Zhang Y.
    Eur J Pharmacol; 2012 Sep 15; 691(1-3):61-8. PubMed ID: 22824464
    [Abstract] [Full Text] [Related]

  • 16. Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species.
    Pan MH, Lai CS, Hsu PC, Wang YJ.
    J Agric Food Chem; 2005 Feb 09; 53(3):620-30. PubMed ID: 15686411
    [Abstract] [Full Text] [Related]

  • 17. Protection of betulin against cadmium-induced apoptosis in hepatoma cells.
    Oh SH, Choi JE, Lim SC.
    Toxicology; 2006 Mar 01; 220(1):1-12. PubMed ID: 16436312
    [Abstract] [Full Text] [Related]

  • 18. Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid.
    Li JJ, Tang Q, Li Y, Hu BR, Ming ZY, Fu Q, Qian JQ, Xiang JZ.
    Acta Pharmacol Sin; 2006 Aug 01; 27(8):1078-84. PubMed ID: 16867262
    [Abstract] [Full Text] [Related]

  • 19. GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.
    Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.
    Eur J Pharmacol; 2011 Nov 16; 670(1):13-21. PubMed ID: 21944925
    [Abstract] [Full Text] [Related]

  • 20. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells.
    Simbula G, Columbano A, Ledda-Columbano GM, Sanna L, Deidda M, Diana A, Pibiri M.
    Apoptosis; 2007 Jan 16; 12(1):113-23. PubMed ID: 17136495
    [Abstract] [Full Text] [Related]

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