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Journal Abstract Search

145 related items for PubMed ID: 2191947

  • 1. N-acetylcolchinol O-methyl ether and thiocolchicine, potent analogs of colchicine modified in the C ring. Evaluation of the mechanistic basis for their enhanced biological properties.
    Kang GJ, Getahun Z, Muzaffar A, Brossi A, Hamel E.
    J Biol Chem; 1990 Jun 25; 265(18):10255-9. PubMed ID: 2191947
    [Abstract] [Full Text] [Related]

  • 2. Association of thiocolchicine with tubulin.
    Chabin RM, Hastie SB.
    Biochem Biophys Res Commun; 1989 Jun 15; 161(2):544-50. PubMed ID: 2735908
    [Abstract] [Full Text] [Related]

  • 3. Roles of colchicine rings B and C in the binding process to tubulin.
    Medrano FJ, Andreu JM, Gorbunoff MJ, Timasheff SN.
    Biochemistry; 1989 Jun 27; 28(13):5589-99. PubMed ID: 2775723
    [Abstract] [Full Text] [Related]

  • 4. Effect of the B ring and the C-7 substituent on the kinetics of colchicinoid-tubulin associations.
    Pyles EA, Hastie SB.
    Biochemistry; 1993 Mar 09; 32(9):2329-36. PubMed ID: 8443174
    [Abstract] [Full Text] [Related]

  • 5. Binding to tubulin of the colchicine analog 2-methoxy-5-(2', 3', 4'-trimethoxyphenyl)tropone. Thermodynamic and kinetic aspects.
    Bane S, Puett D, Macdonald TL, Williams RC.
    J Biol Chem; 1984 Jun 25; 259(12):7391-8. PubMed ID: 6736010
    [Abstract] [Full Text] [Related]

  • 6. Conformation of thiocolchicine and two B-ring-modified analogues bound to tubulin studied with optical spectroscopy.
    Lincoln P, Nordh J, Deinum J, Angström J, Nordén B.
    Biochemistry; 1991 Feb 05; 30(5):1179-87. PubMed ID: 1991097
    [Abstract] [Full Text] [Related]

  • 7. The mechanism of tubulin-colchicine recognition--a kinetic study of the binding of a bicyclic colchicine analogue with a minor modification of the A ring.
    Dumortier C, Potenziano JL, Bane S, Engelborghs Y.
    Eur J Biochem; 1997 Oct 01; 249(1):265-9. PubMed ID: 9363778
    [Abstract] [Full Text] [Related]

  • 8. Novel B-ring modified allocolchicinoids of the NCME series: design, synthesis, antimicrotubule activity and cytotoxicity.
    Bergemann S, Brecht R, Büttner F, Guénard D, Gust R, Seitz G, Stubbs MT, Thoret S.
    Bioorg Med Chem; 2003 Apr 03; 11(7):1269-81. PubMed ID: 12628654
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives.
    Klejborowska G, Urbaniak A, Maj E, Wietrzyk J, Moshari M, Preto J, Tuszynski JA, Chambers TC, Huczyński A.
    Bioorg Med Chem; 2021 Feb 15; 32():116014. PubMed ID: 33465696
    [Abstract] [Full Text] [Related]

  • 10. Different kinetic pathways of the binding of two biphenyl analogues of colchicine to tubulin.
    Dumortier C, Gorbunoff MJ, Andreu JM, Engelborghs Y.
    Biochemistry; 1996 Apr 09; 35(14):4387-95. PubMed ID: 8605187
    [Abstract] [Full Text] [Related]

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  • 15. A thermodynamic study of the interaction of tubulin with colchicine site ligands.
    Menéndez M, Laynez J, Medrano FJ, Andreu JM.
    J Biol Chem; 1989 Oct 05; 264(28):16367-71. PubMed ID: 2777794
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  • 16. Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity.
    Büttner F, Bergemann S, Guénard D, Gust R, Seitz G, Thoret S.
    Bioorg Med Chem; 2005 May 16; 13(10):3497-511. PubMed ID: 15848763
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  • 18. Interaction of tubulin with bifunctional colchicine analogues: an equilibrium study.
    Andreu JM, Gorbunoff MJ, Lee JC, Timasheff SN.
    Biochemistry; 1984 Apr 10; 23(8):1742-52. PubMed ID: 6722122
    [Abstract] [Full Text] [Related]

  • 19. Podophyllotoxin as a probe for the colchicine binding site of tubulin.
    Cortese F, Bhattacharyya B, Wolff J.
    J Biol Chem; 1977 Feb 25; 252(4):1134-40. PubMed ID: 14143
    [Abstract] [Full Text] [Related]

  • 20. Spectroscopic and kinetic features of allocolchicine binding to tubulin.
    Hastie SB.
    Biochemistry; 1989 Sep 19; 28(19):7753-60. PubMed ID: 2611212
    [Abstract] [Full Text] [Related]

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