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200 related items for PubMed ID: 21935437

  • 1. Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.
    Fernández-Trillo J, Barros F, Machín A, Carretero L, Domínguez P, de la Peña P.
    PLoS One; 2011; 6(9):e24674. PubMed ID: 21935437
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  • 3. A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels.
    Gustina AS, Trudeau MC.
    Proc Natl Acad Sci U S A; 2009 Aug 04; 106(31):13082-7. PubMed ID: 19651618
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  • 5. The eag domain regulates hERG channel inactivation gating via a direct interaction.
    Gustina AS, Trudeau MC.
    J Gen Physiol; 2013 Feb 04; 141(2):229-41. PubMed ID: 23319729
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  • 6. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
    Malak OA, Gluhov GS, Grizel AV, Kudryashova KS, Sokolova OS, Loussouarn G.
    J Biol Chem; 2019 Apr 19; 294(16):6506-6521. PubMed ID: 30808709
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  • 7. Mechanistic insight into human ether-à-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
    Muskett FW, Thouta S, Thomson SJ, Bowen A, Stansfeld PJ, Mitcheson JS.
    J Biol Chem; 2011 Feb 25; 286(8):6184-91. PubMed ID: 21135103
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  • 8. hERG potassium channel gating is mediated by N- and C-terminal region interactions.
    Gustina AS, Trudeau MC.
    J Gen Physiol; 2011 Mar 25; 137(3):315-25. PubMed ID: 21357734
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  • 9. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Liu QN, Trudeau MC.
    PLoS One; 2015 Mar 25; 10(4):e0123951. PubMed ID: 25923442
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  • 10. The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels.
    Lin TF, Jow GM, Fang HY, Fu SJ, Wu HH, Chiu MM, Jeng CJ.
    PLoS One; 2014 Mar 25; 9(10):e110423. PubMed ID: 25333352
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  • 11. Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.
    Alonso-Ron C, de la Peña P, Miranda P, Domínguez P, Barros F.
    Biophys J; 2008 May 15; 94(10):3893-911. PubMed ID: 18222997
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  • 14. Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels.
    de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F.
    Biochem J; 2013 May 01; 451(3):463-74. PubMed ID: 23418776
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  • 20. The structural mechanism of KCNH-channel regulation by the eag domain.
    Haitin Y, Carlson AE, Zagotta WN.
    Nature; 2013 Sep 19; 501(7467):444-8. PubMed ID: 23975098
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