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Journal Abstract Search

258 related items for PubMed ID: 21937454

  • 1. GSK3-mediated instability of tubulin polymers is responsible for the failure of immature CD4+CD8+ thymocytes to polarize their MTOC in response to TCR stimulation.
    Cunningham NR, Hinchcliff EM, Kutyavin VI, Beck T, Reid WA, Punt JA.
    Int Immunol; 2011 Nov; 23(11):693-700. PubMed ID: 21937454
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  • 3. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
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  • 4. Ligand-stimulated signaling events in immature CD4+CD8+ thymocytes expressing competent T-cell receptor complexes.
    Nakayama T, Samelson LE, Nakayama Y, Munitz TI, Sheard M, June CH, Singer A.
    Proc Natl Acad Sci U S A; 1991 Nov 15; 88(22):9949-53. PubMed ID: 1719558
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  • 5. Engagement of the external domains of CD45 tyrosine phosphatase can regulate the differentiation of immature CD4+CD8+ thymocytes into mature T cells.
    Benveniste P, Takahama Y, Wiest DL, Nakayama T, Sharrow SO, Singer A.
    Proc Natl Acad Sci U S A; 1994 Jul 19; 91(15):6933-7. PubMed ID: 8041724
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  • 6. Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation.
    Cunningham NR, Artim SC, Fornadel CM, Sellars MC, Edmonson SG, Scott G, Albino F, Mathur A, Punt JA.
    J Immunol; 2006 Nov 15; 177(10):6660-6. PubMed ID: 17082578
    [Abstract] [Full Text] [Related]

  • 7. CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation.
    Gilliland LK, Teh HS, Uckun FM, Norris NA, Teh SJ, Schieven GL, Ledbetter JA.
    J Immunol; 1991 Mar 15; 146(6):1759-65. PubMed ID: 1706380
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  • 9. Negative selection of precursor thymocytes before their differentiation into CD4+CD8+ cells.
    Takahama Y, Shores EW, Singer A.
    Science; 1992 Oct 23; 258(5082):653-6. PubMed ID: 1357752
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  • 11. Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.
    Kearse KP, Roberts JL, Munitz TI, Wiest DL, Nakayama T, Singer A.
    EMBO J; 1994 Oct 03; 13(19):4504-14. PubMed ID: 7925292
    [Abstract] [Full Text] [Related]

  • 12. Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation.
    McKean DJ, Huntoon CJ, Bell MP, Tai X, Sharrow S, Hedin KE, Conley A, Singer A.
    J Immunol; 2001 Mar 01; 166(5):3468-75. PubMed ID: 11207305
    [Abstract] [Full Text] [Related]

  • 13. Immature CD4+CD8+ thymocytes do not polarize lipid rafts in response to TCR-mediated signals.
    Ebert PJ, Baker JF, Punt JA.
    J Immunol; 2000 Nov 15; 165(10):5435-42. PubMed ID: 11067895
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  • 14. Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion.
    Schnittman SM, Denning SM, Greenhouse JJ, Justement JS, Baseler M, Kurtzberg J, Haynes BF, Fauci AS.
    Proc Natl Acad Sci U S A; 1990 Oct 15; 87(19):7727-31. PubMed ID: 2217206
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  • 15. Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes.
    Kearse KP, Wiest DL, Singer A.
    Proc Natl Acad Sci U S A; 1993 Mar 15; 90(6):2438-42. PubMed ID: 7681596
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  • 16. Entry of CD4-CD8- immature thymocytes into the CD4/CD8 developmental pathway is controlled by tyrosine kinase signals that can be provided through TCR components.
    Takahama Y, Hasegawa T, Itohara S, Ball EL, Sheard MA, Hashimoto Y.
    Int Immunol; 1994 Oct 15; 6(10):1505-14. PubMed ID: 7826942
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  • 17. Inefficient cell spreading and cytoskeletal polarization by CD4+CD8+ thymocytes: regulation by the thymic environment.
    Hailman E, Allen PM.
    J Immunol; 2005 Oct 15; 175(8):4847-57. PubMed ID: 16210586
    [Abstract] [Full Text] [Related]

  • 18. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
    Azzam HS, Grinberg A, Lui K, Shen H, Shores EW, Love PE.
    J Exp Med; 1998 Dec 21; 188(12):2301-11. PubMed ID: 9858516
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  • 19. Regulation of Bim by TCR signals in CD4/CD8 double-positive thymocytes.
    Bunin A, Khwaja FW, Kersh GJ.
    J Immunol; 2005 Aug 01; 175(3):1532-9. PubMed ID: 16034091
    [Abstract] [Full Text] [Related]

  • 20. CD5 costimulation up-regulates the signaling to extracellular signal-regulated kinase activation in CD4+CD8+ thymocytes and supports their differentiation to the CD4 lineage.
    Zhou XY, Yashiro-Ohtani Y, Toyo-Oka K, Park CS, Tai XG, Hamaoka T, Fujiwara H.
    J Immunol; 2000 Feb 01; 164(3):1260-8. PubMed ID: 10640739
    [Abstract] [Full Text] [Related]

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