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Journal Abstract Search


310 related items for PubMed ID: 21942922

  • 1. Sustained overexpression of CYP1A1 and 1B1 and steady accumulation of DNA adducts by low-dose, continuous exposure to benzo[a]pyrene by polymeric implants.
    Jeyabalan J, Vadhanam MV, Ravoori S, Gupta RC.
    Chem Res Toxicol; 2011 Nov 21; 24(11):1937-43. PubMed ID: 21942922
    [Abstract] [Full Text] [Related]

  • 2. Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.
    Harrigan JA, McGarrigle BP, Sutter TR, Olson JR.
    Toxicol In Vitro; 2006 Jun 21; 20(4):426-38. PubMed ID: 16198082
    [Abstract] [Full Text] [Related]

  • 3. Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.
    Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW.
    Mol Pharmacol; 2006 Apr 21; 69(4):1103-14. PubMed ID: 16377763
    [Abstract] [Full Text] [Related]

  • 4. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
    Galván N, Teske DE, Zhou G, Moorthy B, MacWilliams PS, Czuprynski CJ, Jefcoate CR.
    Toxicol Appl Pharmacol; 2005 Feb 01; 202(3):244-57. PubMed ID: 15667830
    [Abstract] [Full Text] [Related]

  • 5. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA, Vezina CM, McGarrigle BP, Ersing N, Box HC, Maccubbin AE, Olson JR.
    Toxicol Sci; 2004 Feb 01; 77(2):307-14. PubMed ID: 14691214
    [Abstract] [Full Text] [Related]

  • 6. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
    Kondraganti SR, Fernandez-Salguero P, Gonzalez FJ, Ramos KS, Jiang W, Moorthy B.
    Int J Cancer; 2003 Jan 01; 103(1):5-11. PubMed ID: 12455047
    [Abstract] [Full Text] [Related]

  • 7. Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyrene, 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene.
    Arif JM, Smith WA, Gupta RC.
    Mutat Res; 1997 Aug 01; 378(1-2):31-9. PubMed ID: 9288883
    [Abstract] [Full Text] [Related]

  • 8. Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene.
    Keshava C, Divi RL, Whipkey DL, Frye BL, McCanlies E, Kuo M, Poirier MC, Weston A.
    Cancer Lett; 2005 Apr 28; 221(2):213-24. PubMed ID: 15808407
    [Abstract] [Full Text] [Related]

  • 9. Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.
    Gábelová A, Poláková V, Prochazka G, Kretová M, Poloncová K, Regendová E, Luciaková K, Segerbäck D.
    Toxicol Appl Pharmacol; 2013 Aug 15; 271(1):1-12. PubMed ID: 23639521
    [Abstract] [Full Text] [Related]

  • 10. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels.
    Uno S, Dalton TP, Shertzer HG, Genter MB, Warshawsky D, Talaska G, Nebert DW.
    Biochem Biophys Res Commun; 2001 Dec 21; 289(5):1049-56. PubMed ID: 11741297
    [Abstract] [Full Text] [Related]

  • 11. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene.
    Einem Lindeman T, Poirier MC, Divi RL.
    Mutagenesis; 2011 Sep 21; 26(5):629-35. PubMed ID: 21669939
    [Abstract] [Full Text] [Related]

  • 12. DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene.
    Arif JM, Smith WA, Gupta RC.
    Carcinogenesis; 1999 Jun 21; 20(6):1147-50. PubMed ID: 10357803
    [Abstract] [Full Text] [Related]

  • 13. Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo.
    Schults MA, Chiu RK, Nagle PW, Wilms LC, Kleinjans JC, van Schooten FJ, Godschalk RW.
    Mutagenesis; 2013 Mar 21; 28(2):181-5. PubMed ID: 23325794
    [Abstract] [Full Text] [Related]

  • 14. Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts.
    Cao P, Vadhanam MV, Spencer WA, Cai J, Gupta RC.
    Chem Res Toxicol; 2011 Jun 20; 24(6):877-86. PubMed ID: 21574630
    [Abstract] [Full Text] [Related]

  • 15. Biotransformation of benzo[a]pyrene in Ahr knockout mice is dependent on time and route of exposure.
    Sagredo C, Mollerup S, Cole KJ, Phillips DH, Uppstad H, Øvrebø S.
    Chem Res Toxicol; 2009 Mar 16; 22(3):584-91. PubMed ID: 19216581
    [Abstract] [Full Text] [Related]

  • 16. Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
    Musafia-Jeknic T, Mahadevan B, Pereira C, Baird WM.
    Toxicol Sci; 2005 Dec 16; 88(2):358-66. PubMed ID: 16162842
    [Abstract] [Full Text] [Related]

  • 17. Dibenzanthracenes and benzochrysenes elicit both genotoxic and nongenotoxic events in rat liver 'stem-like' cells.
    Svihálková-Sindlerová L, Machala M, Pencíková K, Marvanová S, Neca J, Topinka J, Sevastyanova O, Kozubík A, Vondrácek J.
    Toxicology; 2007 Mar 22; 232(1-2):147-59. PubMed ID: 17287060
    [Abstract] [Full Text] [Related]

  • 18. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.
    Alexandrov K, Rojas M, Geneste O, Castegnaro M, Camus AM, Petruzzelli S, Giuntini C, Bartsch H.
    Cancer Res; 1992 Nov 15; 52(22):6248-53. PubMed ID: 1423269
    [Abstract] [Full Text] [Related]

  • 19. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
    Jiang H, Shen YM, Quinn AM, Penning TM.
    Chem Res Toxicol; 2005 Feb 15; 18(2):365-74. PubMed ID: 15720144
    [Abstract] [Full Text] [Related]

  • 20. Maternal intake of quercetin during gestation alters ex vivo benzo[a]pyrene metabolism and DNA adduct formation in adult offspring.
    Vanhees K, van Schooten FJ, Moonen EJ, Maas LM, van Waalwijk van Doorn-Khosrovani SB, Godschalk RW.
    Mutagenesis; 2012 Jul 15; 27(4):445-51. PubMed ID: 22334599
    [Abstract] [Full Text] [Related]


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