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431 related items for PubMed ID: 21945488

  • 1. Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).
    Greupink R, Dillen L, Monshouwer M, Huisman MT, Russel FG.
    Eur J Pharm Sci; 2011 Nov 20; 44(4):487-96. PubMed ID: 21945488
    [Abstract] [Full Text] [Related]

  • 2. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Noé J, Portmann R, Brun ME, Funk C.
    Drug Metab Dispos; 2007 Aug 20; 35(8):1308-14. PubMed ID: 17470528
    [Abstract] [Full Text] [Related]

  • 3. Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.
    Gozalpour E, Greupink R, Wortelboer HM, Bilos A, Schreurs M, Russel FG, Koenderink JB.
    Mol Pharm; 2014 Jun 02; 11(6):1844-55. PubMed ID: 24754247
    [Abstract] [Full Text] [Related]

  • 4. Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin.
    Bi YA, Qiu X, Rotter CJ, Kimoto E, Piotrowski M, Varma MV, Ei-Kattan AF, Lai Y.
    Biopharm Drug Dispos; 2013 Nov 02; 34(8):452-61. PubMed ID: 23996477
    [Abstract] [Full Text] [Related]

  • 5. Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.
    Choi MK, Shin HJ, Choi YL, Deng JW, Shin JG, Song IS.
    Xenobiotica; 2011 Jan 02; 41(1):24-34. PubMed ID: 20946088
    [Abstract] [Full Text] [Related]

  • 6. Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity.
    Leslie EM, Watkins PB, Kim RB, Brouwer KL.
    J Pharmacol Exp Ther; 2007 Jun 02; 321(3):1170-8. PubMed ID: 17374746
    [Abstract] [Full Text] [Related]

  • 7. Expression and transport function of drug uptake transporters in differentiated HepaRG cells.
    Kotani N, Maeda K, Debori Y, Camus S, Li R, Chesne C, Sugiyama Y.
    Mol Pharm; 2012 Dec 03; 9(12):3434-41. PubMed ID: 22897388
    [Abstract] [Full Text] [Related]

  • 8. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
    De Bruyn T, Ye ZW, Peeters A, Sahi J, Baes M, Augustijns PF, Annaert PP.
    Eur J Pharm Sci; 2011 Jul 17; 43(4):297-307. PubMed ID: 21605667
    [Abstract] [Full Text] [Related]

  • 9. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
    Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB.
    Gastroenterology; 2006 May 17; 130(6):1793-806. PubMed ID: 16697742
    [Abstract] [Full Text] [Related]

  • 10. Electrophysiological characterization of human Na⁺/taurocholate cotransporting polypeptide (hNTCP) heterologously expressed in Xenopus laevis oocytes.
    Masuda M, Ichikawa Y, Shimono K, Shimizu M, Tanaka Y, Nara T, Miyauchi S.
    Arch Biochem Biophys; 2014 Nov 15; 562():115-21. PubMed ID: 25168282
    [Abstract] [Full Text] [Related]

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  • 12. Characterization of ursodeoxycholic and norursodeoxycholic acid as substrates of the hepatic uptake transporters OATP1B1, OATP1B3, OATP2B1 and NTCP.
    König J, Klatt S, Dilger K, Fromm MF.
    Basic Clin Pharmacol Toxicol; 2012 Aug 15; 111(2):81-6. PubMed ID: 22333292
    [Abstract] [Full Text] [Related]

  • 13. Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.
    Leonhardt M, Keiser M, Oswald S, Kühn J, Jia J, Grube M, Kroemer HK, Siegmund W, Weitschies W.
    Drug Metab Dispos; 2010 Jul 15; 38(7):1024-8. PubMed ID: 20406852
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  • 15. In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.
    Greupink R, Nabuurs SB, Zarzycka B, Verweij V, Monshouwer M, Huisman MT, Russel FG.
    Toxicol Sci; 2012 Sep 15; 129(1):35-48. PubMed ID: 22641618
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  • 17. Hepatocellular organic anion-transporting polypeptides (OATPs) and multidrug resistance-associated protein 2 (MRP2) are inhibited by silibinin.
    Wlcek K, Koller F, Ferenci P, Stieger B.
    Drug Metab Dispos; 2013 Aug 15; 41(8):1522-8. PubMed ID: 23695864
    [Abstract] [Full Text] [Related]

  • 18. Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.
    Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD.
    Drug Metab Dispos; 2010 Jul 15; 38(7):1072-82. PubMed ID: 20360302
    [Abstract] [Full Text] [Related]

  • 19. Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
    Hartman JC, Brouwer K, Mandagere A, Melvin L, Gorczynski R.
    Can J Physiol Pharmacol; 2010 Jun 15; 88(6):682-91. PubMed ID: 20628435
    [Abstract] [Full Text] [Related]

  • 20. Na+-taurocholate cotransporting polypeptide (NTCP/SLC10A1) ortholog in the marine skate Leucoraja erinacea is not a physiological bile salt transporter.
    Yu D, Zhang H, Lionarons DA, Boyer JL, Cai SY.
    Am J Physiol Regul Integr Comp Physiol; 2017 Apr 01; 312(4):R477-R484. PubMed ID: 28077388
    [Abstract] [Full Text] [Related]

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