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Journal Abstract Search

591 related items for PubMed ID: 21954435

  • 1. Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy.
    Roongta UV, Pabalan JG, Wang X, Ryseck RP, Fargnoli J, Henley BJ, Yang WP, Zhu J, Madireddi MT, Lawrence RM, Wong TW, Rupnow BA.
    Mol Cancer Res; 2011 Nov; 9(11):1551-61. PubMed ID: 21954435
    [Abstract] [Full Text] [Related]

  • 2. FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth.
    Du X, Wang QR, Chan E, Merchant M, Liu J, French D, Ashkenazi A, Qing J.
    Cancer Res; 2012 Nov 15; 72(22):5843-55. PubMed ID: 23019225
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of Stearoyl-CoA Desaturase 1 expression in human lung adenocarcinoma cells impairs tumorigenesis.
    Scaglia N, Igal RA.
    Int J Oncol; 2008 Oct 15; 33(4):839-50. PubMed ID: 18813799
    [Abstract] [Full Text] [Related]

  • 4. In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor.
    Nishizawa S, Sumi H, Satoh Y, Yamamoto Y, Kitazawa S, Honda K, Araki H, Kakoi K, Imamura K, Sasaki M, Miyahisa I, Satomi Y, Nishigaki R, Hirayama M, Aoyama K, Maezaki H, Hara T.
    Eur J Pharmacol; 2017 Jul 15; 807():21-31. PubMed ID: 28442322
    [Abstract] [Full Text] [Related]

  • 5. A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids.
    Ntambi JM, Sessler AM, Takova T.
    Biochem Biophys Res Commun; 1996 Mar 27; 220(3):990-5. PubMed ID: 8607881
    [Abstract] [Full Text] [Related]

  • 6. Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells.
    Nashed M, Chisholm JW, Igal RA.
    Exp Biol Med (Maywood); 2012 Sep 27; 237(9):1007-17. PubMed ID: 22946088
    [Abstract] [Full Text] [Related]

  • 7. Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry.
    Soulard P, McLaughlin M, Stevens J, Connolly B, Coli R, Wang L, Moore J, Kuo MS, LaMarr WA, Ozbal CC, Bhat BG.
    Anal Chim Acta; 2008 Oct 03; 627(1):105-11. PubMed ID: 18790133
    [Abstract] [Full Text] [Related]

  • 8. Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity.
    Dillon R, Greig MJ, Bhat BG.
    Anal Chim Acta; 2008 Oct 03; 627(1):99-104. PubMed ID: 18790132
    [Abstract] [Full Text] [Related]

  • 9. Regulation of stearoyl-CoA desaturase activity by the trans-10,cis-12 isomer of conjugated linoleic acid in HepG2 cells.
    Choi Y, Park Y, Pariza MW, Ntambi JM.
    Biochem Biophys Res Commun; 2001 Jun 15; 284(3):689-93. PubMed ID: 11396956
    [Abstract] [Full Text] [Related]

  • 10. Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol.
    Bené H, Lasky D, Ntambi JM.
    Biochem Biophys Res Commun; 2001 Jun 29; 284(5):1194-8. PubMed ID: 11414710
    [Abstract] [Full Text] [Related]

  • 11. Stearoyl-CoA desaturase--a new player in skeletal muscle metabolism regulation.
    Dobrzyń A, Dobrzyń P.
    J Physiol Pharmacol; 2006 Nov 29; 57 Suppl 10():31-42. PubMed ID: 17242489
    [Abstract] [Full Text] [Related]

  • 12. Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart.
    Dobrzyn P, Sampath H, Dobrzyn A, Miyazaki M, Ntambi JM.
    Am J Physiol Endocrinol Metab; 2008 Feb 29; 294(2):E357-64. PubMed ID: 18042664
    [Abstract] [Full Text] [Related]

  • 13. Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells.
    Iwai T, Kume S, Chin-Kanasaki M, Kuwagata S, Araki H, Takeda N, Sugaya T, Uzu T, Maegawa H, Araki SI.
    Int J Mol Sci; 2016 Nov 09; 17(11):. PubMed ID: 27834856
    [Abstract] [Full Text] [Related]

  • 14. Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo.
    Mai K, Andres J, Bobbert T, Assmann A, Biedasek K, Diederich S, Graham I, Larson TR, Pfeiffer AF, Spranger J.
    Metabolism; 2012 Jan 09; 61(1):108-16. PubMed ID: 21741058
    [Abstract] [Full Text] [Related]

  • 15. Overexpression of stearoyl-CoA desaturase-1 results in an increase of conjugated linoleic acid (CLA) and n-7 fatty acids in 293 cells.
    Wu Z, Li D, Gou K.
    Biochem Biophys Res Commun; 2010 Jul 30; 398(3):473-6. PubMed ID: 20599700
    [Abstract] [Full Text] [Related]

  • 16. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates.
    Wang J, Yu L, Schmidt RE, Su C, Huang X, Gould K, Cao G.
    Biochem Biophys Res Commun; 2005 Jul 08; 332(3):735-42. PubMed ID: 15907797
    [Abstract] [Full Text] [Related]

  • 17. Induction of stearoyl-CoA desaturase 2 gene expression correlates with fatty acid changes in phosphatidylcholine.
    Tebbey PW, Van Cleave S, Buttke TM.
    Biochem Mol Biol Int; 1994 Aug 08; 33(5):991-1000. PubMed ID: 7987266
    [Abstract] [Full Text] [Related]

  • 18. Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols.
    Zulkifli RM, Parr T, Salter AM, Brameld JM.
    J Anim Sci; 2010 Aug 08; 88(8):2565-75. PubMed ID: 20382866
    [Abstract] [Full Text] [Related]

  • 19. Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle.
    Dobrzyn A, Dobrzyn P, Lee SH, Miyazaki M, Cohen P, Asilmaz E, Hardie DG, Friedman JM, Ntambi JM.
    Am J Physiol Endocrinol Metab; 2005 Mar 08; 288(3):E599-607. PubMed ID: 15562249
    [Abstract] [Full Text] [Related]

  • 20. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 08; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

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