These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

256 related items for PubMed ID: 21956522

  • 1. Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase I inhibitors.
    Zhu L, Cheng P, Lei N, Yao J, Sheng C, Zhuang C, Guo W, Liu W, Zhang Y, Dong G, Wang S, Miao Z, Zhang W.
    Arch Pharm (Weinheim); 2011 Nov; 344(11):726-34. PubMed ID: 21956522
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
    Zhu L, Zhang X, Lei N, Liu W, Miao Z, Zhuang C, Sheng C, Guo W, Dong G, Yao J, Cheng P, Zhang W.
    Chem Biodivers; 2012 Jun; 9(6):1084-94. PubMed ID: 22700227
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of new homocamptothecin analogs.
    Luo Y, Yu S, Tong L, Huang Q, Lu W, Chen Y.
    Eur J Med Chem; 2012 Aug; 54():281-6. PubMed ID: 22647222
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
    Liu W, Zhu L, Guo W, Zhuang C, Zhang Y, Sheng C, Cheng P, Yao J, Wang W, Dong G, Wang S, Miao Z, Zhang W.
    Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and cytotoxicity of novel 20-O-linked homocamptothecin ester derivatives as potent topoisomerase I inhibitors.
    Li DZ, Wang CY, Liu RH, Wang YM, Ji TF, Li YR, Pan XD.
    J Asian Nat Prod Res; 2013 Nov; 15(11):1179-88. PubMed ID: 24215541
    [Abstract] [Full Text] [Related]

  • 6. Synthesis of 9-(heteroarylmethylidene)amino derivatives of homocamptothecin with biological activities.
    Guo W, Miao Z, Sheng C, Yao J, Liu W, Zhu L, Zhang Y, Cheng P, Dong G, Zhuang C, Zhang W.
    Chem Biodivers; 2011 Jul; 8(7):1266-73. PubMed ID: 21766447
    [Abstract] [Full Text] [Related]

  • 7. Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins.
    Lavergne O, Demarquay D, Bailly C, Lanco C, Rolland A, Huchet M, Coulomb H, Muller N, Baroggi N, Camara J, Le Breton C, Manginot E, Cazaux JB, Bigg DC.
    J Med Chem; 2000 Jun 01; 43(11):2285-9. PubMed ID: 10841808
    [Abstract] [Full Text] [Related]

  • 8. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
    Lesueur-Ginot L, Demarquay D, Kiss R, Kasprzyk PG, Dassonneville L, Bailly C, Camara J, Lavergne O, Bigg DC.
    Cancer Res; 1999 Jun 15; 59(12):2939-43. PubMed ID: 10383158
    [Abstract] [Full Text] [Related]

  • 9. Trifluoromethyl-promoted homocamptothecins: synthesis and biological activity.
    Zhu L, Miao Z, Sheng C, Guo W, Yao J, Liu W, Che X, Wang W, Cheng P, Zhang W.
    Eur J Med Chem; 2010 Jul 15; 45(7):2726-32. PubMed ID: 20304538
    [Abstract] [Full Text] [Related]

  • 10. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
    Bailly C, Lansiaux A, Dassonneville L, Demarquay D, Coulomb H, Huchet M, Lavergne O, Bigg DC.
    Biochemistry; 1999 Nov 23; 38(47):15556-63. PubMed ID: 10569939
    [Abstract] [Full Text] [Related]

  • 11. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P, Zhu L, Guo W, Liu W, Yao J, Dong G, Zhang Y, Zhuang C, Sheng C, Miao Z, Zhang W.
    J Enzyme Inhib Med Chem; 2012 Jun 23; 27(3):437-42. PubMed ID: 21770860
    [Abstract] [Full Text] [Related]

  • 12. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
    Lavergne O, Lesueur-Ginot L, Pla Rodas F, Kasprzyk PG, Pommier J, Demarquay D, Prévost G, Ulibarri G, Rolland A, Schiano-Liberatore AM, Harnett J, Pons D, Camara J, Bigg DC.
    J Med Chem; 1998 Dec 31; 41(27):5410-9. PubMed ID: 9876111
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I.
    Guo W, Miao Z, Sheng C, Yao J, Feng H, Zhang W, Zhu L, Liu W, Cheng P, Zhang J, Che X, Wang W, Luo C, Xu Y.
    Eur J Med Chem; 2010 Jun 31; 45(6):2223-8. PubMed ID: 20202723
    [Abstract] [Full Text] [Related]

  • 14. Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogs.
    Wang L, Huang Y, Zhang J, Tong L, Chen Y, Lu W, Huang Q.
    Bioorg Med Chem Lett; 2014 Mar 15; 24(6):1597-9. PubMed ID: 24529870
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological assays of 9-(acylamino) homocamptothecins as DNA topoisomerase I inhibitors.
    Guo W, Dong G, Zhu L, Liu W, Zhuang C, Guo Z, Yao J, Sheng C, Zhang H, Miao Z, Zhang W.
    Chem Biodivers; 2013 Oct 15; 10(10):1804-15. PubMed ID: 24130024
    [Abstract] [Full Text] [Related]

  • 16. New homocamptothecins: synthesis, antitumor activity, and molecular modeling.
    Miao Z, Sheng C, Zhang W, Ji H, Zhang J, Shao L, You L, Zhang M, Yao J, Che X.
    Bioorg Med Chem; 2008 Feb 01; 16(3):1493-510. PubMed ID: 18207748
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
    Zhang C, Li S, Ji L, Liu S, Li Z, Li S, Meng X.
    Bioorg Med Chem Lett; 2015 Oct 15; 25(20):4693-6. PubMed ID: 26384290
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and antitumor activity of novel substituted uracil-1'(N)-acetic acid ester derivatives of 20(S)-camptothecins.
    Li DZ, Zhang QZ, Wang CY, Zhang YL, Li XY, Huang JT, Liu HY, Fu ZD, Song HX, Lin JP, Ji TF, Pan XD.
    Eur J Med Chem; 2017 Jan 05; 125():1235-1246. PubMed ID: 27871039
    [Abstract] [Full Text] [Related]

  • 19. E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation.
    Giannini G, Marzi M, Cabri W, Marastoni E, Battistuzzi G, Vesci L, Pisano C, Beretta GL, De Cesare M, Zunino F.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2910-5. PubMed ID: 18424133
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.
    Zhao Q, Xu X, Xie Z, Liu X, You Q, Guo Q, Zhong Y, Li Z.
    Bioorg Med Chem Lett; 2016 Feb 01; 26(3):1068-1072. PubMed ID: 26725027
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 13.