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161 related items for PubMed ID: 21956714

  • 1. Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells.
    Chen G, Hu X, Zhang W, Xu N, Wang FQ, Jia J, Zhang WF, Sun ZJ, Zhao YF.
    Apoptosis; 2012 Jan; 17(1):90-101. PubMed ID: 21956714
    [Abstract] [Full Text] [Related]

  • 2. Mammalian target of rapamycin pathway promotes tumor-induced angiogenesis in adenoid cystic carcinoma: its suppression by isoliquiritigenin through dual activation of c-Jun NH2-terminal kinase and inhibition of extracellular signal-regulated kinase.
    Sun ZJ, Chen G, Zhang W, Hu X, Huang CF, Wang YF, Jia J, Zhao YF.
    J Pharmacol Exp Ther; 2010 Aug; 334(2):500-12. PubMed ID: 20484154
    [Abstract] [Full Text] [Related]

  • 3. Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma.
    Sun ZJ, Chen G, Zhang W, Hu X, Liu Y, Zhou Q, Zhu LX, Zhao YF.
    Mol Pharmacol; 2011 Jan; 79(1):106-18. PubMed ID: 20959361
    [Abstract] [Full Text] [Related]

  • 4. Temsirolimus, the mTOR inhibitor, induces autophagy in adenoid cystic carcinoma: in vitro and in vivo.
    Liu W, Huang S, Chen Z, Wang H, Wu H, Zhang D.
    Pathol Res Pract; 2014 Nov; 210(11):764-9. PubMed ID: 24767255
    [Abstract] [Full Text] [Related]

  • 5. Obatoclax induces Beclin 1- and ATG5-dependent apoptosis and autophagy in adenoid cystic carcinoma cells.
    Liang LZ, Ma B, Liang YJ, Liu HC, Zhang TH, Zheng GS, Su YX, Liao GQ.
    Oral Dis; 2015 May; 21(4):470-7. PubMed ID: 25482163
    [Abstract] [Full Text] [Related]

  • 6. Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin.
    Sun ZJ, Chen G, Hu X, Zhang W, Liu Y, Zhu LX, Zhou Q, Zhao YF.
    Apoptosis; 2010 Jul; 15(7):850-63. PubMed ID: 20386985
    [Abstract] [Full Text] [Related]

  • 7. Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway.
    Yo YT, Shieh GS, Hsu KF, Wu CL, Shiau AL.
    J Agric Food Chem; 2009 Sep 23; 57(18):8266-73. PubMed ID: 19711916
    [Abstract] [Full Text] [Related]

  • 8. Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
    Liu S, Zhu L, Zhang J, Yu J, Cheng X, Peng B.
    Biochem Pharmacol; 2016 Apr 15; 106():82-93. PubMed ID: 26947453
    [Abstract] [Full Text] [Related]

  • 9. ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro.
    Song L, Luo Y, Li S, Hong M, Wang Q, Chi X, Yang C.
    Drug Des Devel Ther; 2020 Apr 15; 14():4363-4376. PubMed ID: 33116421
    [Abstract] [Full Text] [Related]

  • 10. Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
    Zhang XR, Wang SY, Sun W, Wei C.
    Mol Med Rep; 2018 Sep 15; 18(3):3429-3436. PubMed ID: 30066879
    [Abstract] [Full Text] [Related]

  • 11. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.
    Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.
    Cancer Res; 2009 Apr 15; 69(8):3704-12. PubMed ID: 19336571
    [Abstract] [Full Text] [Related]

  • 12. Dual inhibitor of phosphoinositide 3-kinase/mammalian target of rapamycin NVP-BEZ235 effectively inhibits cisplatin-resistant urothelial cancer cell growth through autophagic flux.
    Li JR, Cheng CL, Yang CR, Ou YC, Wu MJ, Ko JL.
    Toxicol Lett; 2013 Jul 18; 220(3):267-76. PubMed ID: 23651616
    [Abstract] [Full Text] [Related]

  • 13. Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells.
    Xi G, Hu X, Wu B, Jiang H, Young CY, Pang Y, Yuan H.
    Cancer Lett; 2011 Aug 28; 307(2):141-8. PubMed ID: 21511395
    [Abstract] [Full Text] [Related]

  • 14. Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression.
    Kim YS, Jin HO, Seo SK, Woo SH, Choe TB, An S, Hong SI, Lee SJ, Lee KH, Park IC.
    Biochem Pharmacol; 2011 Aug 01; 82(3):216-26. PubMed ID: 21601561
    [Abstract] [Full Text] [Related]

  • 15. Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
    He J, Peng H, Wang M, Liu Y, Guo X, Wang B, Dai L, Cheng X, Meng Z, Yuan L, Cai F, Tang Y.
    Acta Biochim Biophys Sin (Shanghai); 2020 Aug 05; 52(8):810-820. PubMed ID: 32638014
    [Abstract] [Full Text] [Related]

  • 16. YL4073 is a potent autophagy-stimulating antitumor agent in an in vivo model of Lewis lung carcinoma.
    Xu YZ, Li YH, Lu WJ, Lu K, Wang CT, Li Y, Lin HJ, Kan LX, Yang SY, Wang SY, Zhao YL.
    Oncol Rep; 2016 Apr 05; 35(4):2081-8. PubMed ID: 26847587
    [Abstract] [Full Text] [Related]

  • 17. Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.
    Chu PM, Chen LH, Chen MT, Ma HI, Su TL, Hsieh PC, Chien CS, Jiang BH, Chen YC, Lin YH, Shih YH, Tu PH, Chiou SH.
    Cancer Chemother Pharmacol; 2012 Mar 05; 69(3):621-33. PubMed ID: 21947203
    [Abstract] [Full Text] [Related]

  • 18. Association between high expression of phosphorylated Akt and mammalian target of rapamycin and improved survival in salivary gland adenoid cystic carcinoma.
    Ouyang DQ, Liang LZ, Ke ZF, Zheng GS, Weng DS, Yang WF, Su YX, Liao GQ.
    Head Neck; 2017 Jun 05; 39(6):1145-1154. PubMed ID: 28230926
    [Abstract] [Full Text] [Related]

  • 19. Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice.
    Wu CH, Chen HY, Wang CW, Shieh TM, Huang TC, Lin LC, Wang KL, Hsia SM.
    Oncotarget; 2016 Nov 08; 7(45):73432-73447. PubMed ID: 27708238
    [Abstract] [Full Text] [Related]

  • 20. Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.
    Yu CC, Chiang PC, Lu PH, Kuo MT, Wen WC, Chen P, Guh JH.
    J Nutr Biochem; 2012 Aug 08; 23(8):900-7. PubMed ID: 21840189
    [Abstract] [Full Text] [Related]

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