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Journal Abstract Search

164 related items for PubMed ID: 21959082

  • 1. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
    Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsy Behav; 2011 Nov; 22(3):461-8. PubMed ID: 21959082
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.
    Shekh-Ahmad T, Bialer M, Yavin E.
    Epilepsy Res; 2012 Feb; 98(2-3):238-46. PubMed ID: 22057163
    [Abstract] [Full Text] [Related]

  • 4. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
    [Abstract] [Full Text] [Related]

  • 5. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.
    Hen N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2010 May 27; 53(10):4177-86. PubMed ID: 20420384
    [Abstract] [Full Text] [Related]

  • 6. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A, Noyori H, Yagen B, Shimshoni JA, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct 27; 86(5):394-401. PubMed ID: 19830722
    [Abstract] [Full Text] [Related]

  • 7. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
    Epilepsia; 2014 Dec 27; 55(12):1944-52. PubMed ID: 25442425
    [Abstract] [Full Text] [Related]

  • 8. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2009 Apr 23; 52(8):2233-42. PubMed ID: 19296679
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues.
    Kaufmann D, Bialer M, Shimshoni JA, Devor M, Yagen B.
    J Med Chem; 2009 Nov 26; 52(22):7236-48. PubMed ID: 19877649
    [Abstract] [Full Text] [Related]

  • 10. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul 26; 49(7):1202-12. PubMed ID: 18435754
    [Abstract] [Full Text] [Related]

  • 11. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
    Gravemann U, Volland J, Nau H.
    Neurotoxicol Teratol; 2008 Jul 26; 30(5):390-4. PubMed ID: 18455366
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
    Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M.
    Neuropharmacology; 2010 Jun 26; 58(8):1228-36. PubMed ID: 20230843
    [Abstract] [Full Text] [Related]

  • 13. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
    Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M.
    Epilepsia; 2014 Feb 26; 55(2):353-61. PubMed ID: 24313671
    [Abstract] [Full Text] [Related]

  • 14. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
    White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M.
    Epilepsia; 2012 Jan 26; 53(1):134-46. PubMed ID: 22150444
    [Abstract] [Full Text] [Related]

  • 15. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
    Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M.
    Epilepsy Res; 2007 Jan 26; 73(1):75-84. PubMed ID: 16997532
    [Abstract] [Full Text] [Related]

  • 16. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2007 Dec 13; 50(25):6419-27. PubMed ID: 17994680
    [Abstract] [Full Text] [Related]

  • 17. Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats.
    Mareš P, Kubová H, Hen N, Yagen B, Bialer M.
    Epilepsy Res; 2013 Sep 13; 106(1-2):64-73. PubMed ID: 23815889
    [Abstract] [Full Text] [Related]

  • 18. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
    Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M.
    Epilepsy Behav; 2015 May 13; 46():72-8. PubMed ID: 25863940
    [Abstract] [Full Text] [Related]

  • 19. The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Yagen B, Bialer M.
    Epilepsy Behav; 2015 Aug 13; 49():298-302. PubMed ID: 25979572
    [Abstract] [Full Text] [Related]

  • 20. Assessment of seizure susceptibility in pilocarpine epileptic and nonepileptic Wistar rats and of seizure reinduction with pentylenetetrazole and electroshock models.
    Blanco MM, dos Santos JG, Perez-Mendes P, Kohek SR, Cavarsan CF, Hummel M, Albuquerque C, Mello LE.
    Epilepsia; 2009 Apr 13; 50(4):824-31. PubMed ID: 19054404
    [Abstract] [Full Text] [Related]

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