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Journal Abstract Search

391 related items for PubMed ID: 21967060

  • 1. Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy.
    Kim Chiaw P, Eckford PD, Bear CE.
    Essays Biochem; 2011 Sep 07; 50(1):233-48. PubMed ID: 21967060
    [Abstract] [Full Text] [Related]

  • 2. Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone.
    Scott-Ward TS, Amaral MD.
    FEBS J; 2009 Dec 07; 276(23):7097-109. PubMed ID: 19878303
    [Abstract] [Full Text] [Related]

  • 3. Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease.
    Pasyk S, Li C, Ramjeesingh M, Bear CE.
    Biochem J; 2009 Feb 15; 418(1):185-90. PubMed ID: 18945216
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  • 6. Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms.
    Roxo-Rosa M, Xu Z, Schmidt A, Neto M, Cai Z, Soares CM, Sheppard DN, Amaral MD.
    Proc Natl Acad Sci U S A; 2006 Nov 21; 103(47):17891-6. PubMed ID: 17098864
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  • 8. HGF stimulation of Rac1 signaling enhances pharmacological correction of the most prevalent cystic fibrosis mutant F508del-CFTR.
    Moniz S, Sousa M, Moraes BJ, Mendes AI, Palma M, Barreto C, Fragata JI, Amaral MD, Matos P.
    ACS Chem Biol; 2013 Feb 15; 8(2):432-42. PubMed ID: 23148778
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  • 9. Cystic fibrosis transmembrane conductance regulator (CFTR) and renal function.
    Stanton BA.
    Wien Klin Wochenschr; 1997 Jun 27; 109(12-13):457-64. PubMed ID: 9261986
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  • 10. Impact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating.
    Cai Z, Palmai-Pallag T, Khuituan P, Mutolo MJ, Boinot C, Liu B, Scott-Ward TS, Callebaut I, Harris A, Sheppard DN.
    J Physiol; 2015 Jun 01; 593(11):2427-46. PubMed ID: 25763566
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  • 12. Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant.
    Yu W, Kim Chiaw P, Bear CE.
    J Biol Chem; 2011 Jul 15; 286(28):24714-25. PubMed ID: 21602569
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  • 14. Mutation specific therapy in CF.
    Kerem E.
    Paediatr Respir Rev; 2006 Jul 15; 7 Suppl 1():S166-9. PubMed ID: 16798551
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  • 15. Abnormal spatial diffusion of Ca2+ in F508del-CFTR airway epithelial cells.
    Antigny F, Norez C, Cantereau A, Becq F, Vandebrouck C.
    Respir Res; 2008 Oct 30; 9(1):70. PubMed ID: 18973672
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  • 16. [Cystic fibrosis].
    Yoshimura K, Anzai C.
    Nihon Rinsho; 1996 Mar 30; 54(3):825-33. PubMed ID: 8904244
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  • 17. Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners.
    Li C, Naren AP.
    Pharmacol Ther; 2005 Nov 30; 108(2):208-23. PubMed ID: 15936089
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  • 18. Potentiation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl- currents by the chemical solvent tetrahydrofuran.
    Hughes LK, Ju M, Sheppard DN.
    Mol Membr Biol; 2008 Sep 30; 25(6-7):528-38. PubMed ID: 18989824
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  • 19. Turnover of the cystic fibrosis transmembrane conductance regulator (CFTR): slow degradation of wild-type and delta F508 CFTR in surface membrane preparations of immortalized airway epithelial cells.
    Wei X, Eisman R, Xu J, Harsch AD, Mulberg AE, Bevins CL, Glick MC, Scanlin TF.
    J Cell Physiol; 1996 Aug 30; 168(2):373-84. PubMed ID: 8707873
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  • 20. The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.
    Farinha CM, Nogueira P, Mendes F, Penque D, Amaral MD.
    Biochem J; 2002 Sep 15; 366(Pt 3):797-806. PubMed ID: 12069690
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