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1439 related items for PubMed ID: 21992552

  • 1. A novel glycogen synthase kinase-3 inhibitor 2-methyl-5-(3-{4-[(S )-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer's disease.
    Onishi T, Iwashita H, Uno Y, Kunitomo J, Saitoh M, Kimura E, Fujita H, Uchiyama N, Kori M, Takizawa M.
    J Neurochem; 2011 Dec; 119(6):1330-40. PubMed ID: 21992552
    [Abstract] [Full Text] [Related]

  • 2. L-3-n-butylphthalide reduces tau phosphorylation and improves cognitive deficits in AβPP/PS1-Alzheimer's transgenic mice.
    Peng Y, Hu Y, Xu S, Li P, Li J, Lu L, Yang H, Feng N, Wang L, Wang X.
    J Alzheimers Dis; 2012 Dec; 29(2):379-91. PubMed ID: 22233765
    [Abstract] [Full Text] [Related]

  • 3. Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.
    Durairajan SS, Liu LF, Lu JH, Chen LL, Yuan Q, Chung SK, Huang L, Li XS, Huang JD, Li M.
    Neurobiol Aging; 2012 Dec; 33(12):2903-19. PubMed ID: 22459600
    [Abstract] [Full Text] [Related]

  • 4. Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.
    Clausen A, Xu X, Bi X, Baudry M.
    J Alzheimers Dis; 2012 Dec; 30(1):183-208. PubMed ID: 22406441
    [Abstract] [Full Text] [Related]

  • 5. Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice.
    Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M, Riederer P, Hoyer S.
    J Alzheimers Dis; 2010 Dec; 19(2):691-704. PubMed ID: 20110613
    [Abstract] [Full Text] [Related]

  • 6. Propranolol reduces cognitive deficits, amyloid and tau pathology in Alzheimer's transgenic mice.
    Dobarro M, Gerenu G, Ramírez MJ.
    Int J Neuropsychopharmacol; 2013 Nov; 16(10):2245-57. PubMed ID: 23768694
    [Abstract] [Full Text] [Related]

  • 7. Xanthoceraside rescues learning and memory deficits through attenuating beta-amyloid deposition and tau hyperphosphorylation in APP mice.
    Jin G, Wang LH, Ji XF, Chi TY, Qi Y, Jiao Q, Xu Q, Zhou XY, Zhang R, Zou LB.
    Neurosci Lett; 2014 Jun 24; 573():58-63. PubMed ID: 24810883
    [Abstract] [Full Text] [Related]

  • 8. Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease.
    Wu X, Kosaraju J, Zhou W, Tam KY.
    ACS Chem Neurosci; 2017 Mar 15; 8(3):676-685. PubMed ID: 28032988
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological modulation of GSAP reduces amyloid-β levels and tau phosphorylation in a mouse model of Alzheimer's disease with plaques and tangles.
    Chu J, Lauretti E, Craige CP, Praticò D.
    J Alzheimers Dis; 2014 Mar 15; 41(3):729-37. PubMed ID: 24662099
    [Abstract] [Full Text] [Related]

  • 10. Valproic Acid Modifies Synaptic Structure and Accelerates Neurite Outgrowth Via the Glycogen Synthase Kinase-3β Signaling Pathway in an Alzheimer's Disease Model.
    Long ZM, Zhao L, Jiang R, Wang KJ, Luo SF, Zheng M, Li XF, He GQ.
    CNS Neurosci Ther; 2015 Nov 15; 21(11):887-97. PubMed ID: 26385876
    [Abstract] [Full Text] [Related]

  • 11. Isorhynchophylline treatment improves the amyloid-β-induced cognitive impairment in rats via inhibition of neuronal apoptosis and tau protein hyperphosphorylation.
    Xian YF, Mao QQ, Wu JC, Su ZR, Chen JN, Lai XP, Ip SP, Lin ZX.
    J Alzheimers Dis; 2014 Nov 15; 39(2):331-46. PubMed ID: 24164737
    [Abstract] [Full Text] [Related]

  • 12. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.
    J Neurosci Res; 2006 May 15; 83(7):1252-61. PubMed ID: 16511867
    [Abstract] [Full Text] [Related]

  • 13. A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.
    Serenó L, Coma M, Rodríguez M, Sánchez-Ferrer P, Sánchez MB, Gich I, Agulló JM, Pérez M, Avila J, Guardia-Laguarta C, Clarimón J, Lleó A, Gómez-Isla T.
    Neurobiol Dis; 2009 Sep 15; 35(3):359-67. PubMed ID: 19523516
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  • 16. The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer's disease in vitro and in vivo.
    Leirós M, Alonso E, Rateb ME, Ebel R, Jaspars M, Alfonso A, Botana LM.
    Neuroscience; 2015 Oct 01; 305():26-35. PubMed ID: 26247694
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  • 19. Role of glycogen synthase kinase-3 in Alzheimer's disease pathogenesis and glycogen synthase kinase-3 inhibitors.
    Avila J, Wandosell F, Hernández F.
    Expert Rev Neurother; 2010 May 01; 10(5):703-10. PubMed ID: 20420491
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  • 20. Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model.
    Herline K, Prelli F, Mehta P, MacMurray C, Goñi F, Wisniewski T.
    Alzheimers Res Ther; 2018 Jun 18; 10(1):54. PubMed ID: 29914551
    [Abstract] [Full Text] [Related]

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