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448 related items for PubMed ID: 21997969

  • 1. Activation of p53 signaling and inhibition of androgen receptor mediate tanshinone IIA induced G1 arrest in LNCaP prostate cancer cells.
    Won SH, Lee HJ, Jeong SJ, Lü J, Kim SH.
    Phytother Res; 2012 May; 26(5):669-74. PubMed ID: 21997969
    [Abstract] [Full Text] [Related]

  • 2. Tanshinone IIA inhibits human prostate cancer cells growth by induction of endoplasmic reticulum stress in vitro and in vivo.
    Chiu SC, Huang SY, Chen SP, Su CC, Chiu TL, Pang CY.
    Prostate Cancer Prostatic Dis; 2013 Dec; 16(4):315-22. PubMed ID: 24042854
    [Abstract] [Full Text] [Related]

  • 3. Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.
    Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.
    Biol Pharm Bull; 2010 Dec; 33(11):1828-34. PubMed ID: 21048307
    [Abstract] [Full Text] [Related]

  • 4. Tanshinone IIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo.
    Chen J, Shi DY, Liu SL, Zhong L.
    Oncol Rep; 2012 Feb; 27(2):523-8. PubMed ID: 22038415
    [Abstract] [Full Text] [Related]

  • 5. Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.
    Zhang Y, Won SH, Jiang C, Lee HJ, Jeong SJ, Lee EO, Zhang J, Ye M, Kim SH, Lü J.
    Pharm Res; 2012 Jun; 29(6):1595-608. PubMed ID: 22281759
    [Abstract] [Full Text] [Related]

  • 6. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
    Lin HP, Lin CY, Huo C, Hsiao PH, Su LC, Jiang SS, Chan TM, Chang CH, Chen LT, Kung HJ, Wang HD, Chuu CP.
    Oncotarget; 2015 Mar 30; 6(9):6684-707. PubMed ID: 25788262
    [Abstract] [Full Text] [Related]

  • 7. Tanshinone IIA inhibits gastric carcinoma AGS cells through increasing p-p38, p-JNK and p53 but reducing p-ERK, CDC2 and cyclin B1 expression.
    Su CC.
    Anticancer Res; 2014 Dec 30; 34(12):7097-110. PubMed ID: 25503137
    [Abstract] [Full Text] [Related]

  • 8. Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells.
    Hååg P, Bektic J, Bartsch G, Klocker H, Eder IE.
    J Steroid Biochem Mol Biol; 2005 Aug 30; 96(3-4):251-8. PubMed ID: 15982869
    [Abstract] [Full Text] [Related]

  • 9. Antiandrogenic, maspin induction, and antiprostate cancer activities of tanshinone IIA and its novel derivatives with modification in ring A.
    Liu W, Zhou J, Geng G, Shi Q, Sauriol F, Wu JH.
    J Med Chem; 2012 Jan 26; 55(2):971-5. PubMed ID: 22175694
    [Abstract] [Full Text] [Related]

  • 10. Anabolic effect of the traditional Chinese medicine compound tanshinone IIA on myotube hypertrophy is mediated by estrogen receptor.
    Zhao P, Soukup ST, Hegevoss J, Ngueu S, Kulling SE, Diel P.
    Planta Med; 2015 May 26; 81(7):578-85. PubMed ID: 26018796
    [Abstract] [Full Text] [Related]

  • 11. The prevention and treatment effects of tanshinone IIA on oestrogen/androgen-induced benign prostatic hyperplasia in rats.
    Wang C, Du X, Yang R, Liu J, Xu D, Shi J, Chen L, Shao R, Fan G, Gao X, Tian G, Zhu Y, Zhang J.
    J Steroid Biochem Mol Biol; 2015 Jan 26; 145():28-37. PubMed ID: 25290459
    [Abstract] [Full Text] [Related]

  • 12. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
    Liu W, Dai Q, Lu N, Wei L, Ha J, Rong J, Mu R, You Q, Li Z, Guo Q.
    Biochem Cell Biol; 2011 Jun 26; 89(3):287-98. PubMed ID: 21491996
    [Abstract] [Full Text] [Related]

  • 13. Piperazine-designed alpha 1A/alpha 1D-adrenoceptor blocker KMUP-1 and doxazosin provide down-regulation of androgen receptor and PSA in prostatic LNCaP cells growth and specifically in xenografts.
    Liu CM, Lo YC, Tai MH, Wu BN, Wu WJ, Chou YH, Chai CY, Huang CH, Chen IJ.
    Prostate; 2009 May 01; 69(6):610-23. PubMed ID: 19143029
    [Abstract] [Full Text] [Related]

  • 14. [Effect of compound Chinese traditional medicine PC-SPES II in inhibiting proliferation of human prostate cancer cell LNCaP and on expressions of AR and PSA].
    Zhang BY, Li YF, Lai Y, Li YS, Chen ZJ.
    Zhongguo Zhong Yao Za Zhi; 2015 Mar 01; 40(5):950-6. PubMed ID: 26087562
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth.
    Mashima T, Okabe S, Seimiya H.
    Mol Pharmacol; 2010 Nov 01; 78(5):846-54. PubMed ID: 20709811
    [Abstract] [Full Text] [Related]

  • 16. Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase.
    Yu P, Duan X, Cheng Y, Liu C, Chen Y, Liu W, Yin B, Wang X, Tao Z.
    Int J Mol Med; 2017 Nov 01; 40(5):1426-1434. PubMed ID: 28901378
    [Abstract] [Full Text] [Related]

  • 17. Induction of G1 arrest and apoptosis in androgen-dependent human prostate cancer by Kuguacin J, a triterpenoid from Momordica charantia leaf.
    Pitchakarn P, Suzuki S, Ogawa K, Pompimon W, Takahashi S, Asamoto M, Limtrakul P, Shirai T.
    Cancer Lett; 2011 Jul 28; 306(2):142-50. PubMed ID: 21429659
    [Abstract] [Full Text] [Related]

  • 18. Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells.
    Lee MS, Lee SO, Kim SH, Lee EO, Lee HJ.
    Int J Mol Sci; 2016 Jul 07; 17(7):. PubMed ID: 27399684
    [Abstract] [Full Text] [Related]

  • 19. Fenofibrate down-regulates the expressions of androgen receptor (AR) and AR target genes and induces oxidative stress in the prostate cancer cell line LNCaP.
    Zhao H, Zhu C, Qin C, Tao T, Li J, Cheng G, Li P, Cao Q, Meng X, Ju X, Shao P, Hua L, Gu M, Yin C.
    Biochem Biophys Res Commun; 2013 Mar 08; 432(2):320-5. PubMed ID: 23399562
    [Abstract] [Full Text] [Related]

  • 20. Zanthoxyli Fructus induces growth arrest and apoptosis of LNCaP human prostate cancer cells in vitro and in vivo in association with blockade of the AKT and AR signal pathways.
    Yang Y, Ikezoe T, Takeuchi T, Adachi Y, Ohtsuki Y, Koeffler HP, Taguchi H.
    Oncol Rep; 2006 Jun 08; 15(6):1581-90. PubMed ID: 16685399
    [Abstract] [Full Text] [Related]

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