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Journal Abstract Search

183 related items for PubMed ID: 21998011

  • 1. Enhancement of TGF-β signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.
    Sharma V, Antonacopoulou AG, Tanaka S, Panoutsopoulos AA, Bravou V, Kalofonos HP, Episkopou V.
    Cancer Res; 2011 Oct 15; 71(20):6438-49. PubMed ID: 21998011
    [Abstract] [Full Text] [Related]

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  • 3. RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity.
    Koinuma D, Shinozaki M, Nagano Y, Ikushima H, Horiguchi K, Goto K, Chano T, Saitoh M, Imamura T, Miyazono K, Miyazawa K.
    J Biol Chem; 2011 Sep 16; 286(37):32502-12. PubMed ID: 21795712
    [Abstract] [Full Text] [Related]

  • 4. Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
    Levy L, Howell M, Das D, Harkin S, Episkopou V, Hill CS.
    Mol Cell Biol; 2007 Sep 16; 27(17):6068-83. PubMed ID: 17591695
    [Abstract] [Full Text] [Related]

  • 5. Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation.
    Erker Y, Neyret-Kahn H, Seeler JS, Dejean A, Atfi A, Levy L.
    Mol Cell Biol; 2013 Jun 16; 33(11):2163-77. PubMed ID: 23530056
    [Abstract] [Full Text] [Related]

  • 6. Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.
    Mavrakis KJ, Andrew RL, Lee KL, Petropoulou C, Dixon JE, Navaratnam N, Norris DP, Episkopou V.
    PLoS Biol; 2007 Mar 16; 5(3):e67. PubMed ID: 17341133
    [Abstract] [Full Text] [Related]

  • 7. Arkadia regulates tumor metastasis by modulation of the TGF-β pathway.
    Briones-Orta MA, Levy L, Madsen CD, Das D, Erker Y, Sahai E, Hill CS.
    Cancer Res; 2013 Mar 15; 73(6):1800-10. PubMed ID: 23467611
    [Abstract] [Full Text] [Related]

  • 8. Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.
    Nagano Y, Koinuma D, Miyazawa K, Miyazono K.
    J Biochem; 2010 Apr 15; 147(4):545-54. PubMed ID: 19959502
    [Abstract] [Full Text] [Related]

  • 9. A Residue Specific Insight into the Arkadia E3 Ubiquitin Ligase Activity and Conformational Plasticity.
    Birkou M, Chasapis CT, Marousis KD, Loutsidou AK, Bentrop D, Lelli M, Herrmann T, Carthy JM, Episkopou V, Spyroulias GA.
    J Mol Biol; 2017 Jul 21; 429(15):2373-2386. PubMed ID: 28647409
    [Abstract] [Full Text] [Related]

  • 10. Arkadia represses the expression of myoblast differentiation markers through degradation of Ski and the Ski-bound Smad complex in C2C12 myoblasts.
    Yuzawa H, Koinuma D, Maeda S, Yamamoto K, Miyazawa K, Imamura T.
    Bone; 2009 Jan 21; 44(1):53-60. PubMed ID: 18950738
    [Abstract] [Full Text] [Related]

  • 11. The four and a half LIM-only protein 2 (FHL2) activates transforming growth factor β (TGF-β) signaling by regulating ubiquitination of the E3 ligase Arkadia.
    Xia T, Lévy L, Levillayer F, Jia B, Li G, Neuveut C, Buendia MA, Lan K, Wei Y.
    J Biol Chem; 2013 Jan 18; 288(3):1785-94. PubMed ID: 23212909
    [Abstract] [Full Text] [Related]

  • 12. Effects of Arkadia on airway remodeling through enhancing TGF-beta signaling in allergic rats.
    Li XZ, Feng JT, Hu CP, Chen ZQ, Gu QH, Nie HP.
    Lab Invest; 2010 Jul 18; 90(7):997-1003. PubMed ID: 20386537
    [Abstract] [Full Text] [Related]

  • 13. Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling.
    Nagano Y, Mavrakis KJ, Lee KL, Fujii T, Koinuma D, Sase H, Yuki K, Isogaya K, Saitoh M, Imamura T, Episkopou V, Miyazono K, Miyazawa K.
    J Biol Chem; 2007 Jul 13; 282(28):20492-501. PubMed ID: 17510063
    [Abstract] [Full Text] [Related]

  • 14. Arkadia-SKI/SnoN signaling differentially regulates TGF-β-induced iTreg and Th17 cell differentiation.
    Xu H, Wu L, Nguyen HH, Mesa KR, Raghavan V, Episkopou V, Littman DR.
    J Exp Med; 2021 Nov 01; 218(11):. PubMed ID: 34473197
    [Abstract] [Full Text] [Related]

  • 15. Regulation of TGF-beta family signaling by E3 ubiquitin ligases.
    Inoue Y, Imamura T.
    Cancer Sci; 2008 Nov 01; 99(11):2107-12. PubMed ID: 18808420
    [Abstract] [Full Text] [Related]

  • 16. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G, Komuro A, Goto K, Shinozaki M, Miyazawa K, Miyazono K, Imamura T.
    Biochem J; 2005 Mar 15; 386(Pt 3):461-70. PubMed ID: 15496141
    [Abstract] [Full Text] [Related]

  • 17. NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligase.
    Chasapis CT, Kandias NG, Episkopou V, Bentrop D, Spyroulias GA.
    Proteins; 2012 May 15; 80(5):1484-9. PubMed ID: 22411132
    [Abstract] [Full Text] [Related]

  • 18. RNF111/Arkadia is regulated by DNA methylation and affects TGF-β/Smad signaling associated invasion in NSCLC cells.
    Chen H, Yang T, Lei Z, Wang L, Yang H, Tong X, Yang WT, Zhao J, Gu Y, Chen Y, Zhang HT.
    Lung Cancer; 2015 Oct 15; 90(1):32-40. PubMed ID: 26238425
    [Abstract] [Full Text] [Related]

  • 19. The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.
    Seo SR, Lallemand F, Ferrand N, Pessah M, L'Hoste S, Camonis J, Atfi A.
    EMBO J; 2004 Oct 01; 23(19):3780-92. PubMed ID: 15359284
    [Abstract] [Full Text] [Related]

  • 20. Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.
    Le Scolan E, Zhu Q, Wang L, Bandyopadhyay A, Javelaud D, Mauviel A, Sun L, Luo K.
    Cancer Res; 2008 May 01; 68(9):3277-85. PubMed ID: 18451154
    [Abstract] [Full Text] [Related]

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