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419 related items for PubMed ID: 22005449

  • 1. Gold(I) complexes with thiosemicarbazones: cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA, Guerra JC, de Miranda LF, Romeiro CF, Da Silva JG, Mendes IC, Speziali NL, Souza-Fagundes EM, Beraldo H.
    J Inorg Biochem; 2011 Dec; 105(12):1729-39. PubMed ID: 22005449
    [Abstract] [Full Text] [Related]

  • 2. Spectroscopic and electrochemical characterization of gold(I) and gold(III) complexes with glyoxaldehyde bis(thiosemicarbazones): cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA, Ferraz KS, Guerra JC, de Miranda LF, Romeiro CF, Souza-Fagundes EM, Barbeira PJ, Beraldo H.
    Biometals; 2012 Jun; 25(3):587-98. PubMed ID: 22526562
    [Abstract] [Full Text] [Related]

  • 3. Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex.
    Sâmia LB, Parrilha GL, Da Silva JG, Ramos JP, Souza-Fagundes EM, Castelli S, Vutey V, Desideri A, Beraldo H.
    Biometals; 2016 Jun; 29(3):515-26. PubMed ID: 27091443
    [Abstract] [Full Text] [Related]

  • 4. Antimony(III) complexes with 2-benzoylpyridine-derived thiosemicarbazones: cytotoxicity against human leukemia cell lines.
    Reis DC, Pinto MC, Souza-Fagundes EM, Wardell SM, Wardell JL, Beraldo H.
    Eur J Med Chem; 2010 Sep; 45(9):3904-10. PubMed ID: 20576328
    [Abstract] [Full Text] [Related]

  • 5. Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents.
    Schuh E, Pflüger C, Citta A, Folda A, Rigobello MP, Bindoli A, Casini A, Mohr F.
    J Med Chem; 2012 Jun 14; 55(11):5518-28. PubMed ID: 22621714
    [Abstract] [Full Text] [Related]

  • 6. Structural studies and cytotoxic activity of N(4)-phenyl-2-benzoylpyridine thiosemicarbazone Sn(IV) complexes.
    Perez-Rebolledo A, Ayala JD, de Lima GM, Marchini N, Bombieri G, Zani CL, Souza-Fagundes EM, Beraldo H.
    Eur J Med Chem; 2005 May 14; 40(5):467-72. PubMed ID: 15893020
    [Abstract] [Full Text] [Related]

  • 7. NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents.
    Liu W, Bensdorf K, Proetto M, Abram U, Hagenbach A, Gust R.
    J Med Chem; 2011 Dec 22; 54(24):8605-15. PubMed ID: 22091836
    [Abstract] [Full Text] [Related]

  • 8. Benzimidazol-2-ylidene gold(I) complexes are thioredoxin reductase inhibitors with multiple antitumor properties.
    Rubbiani R, Kitanovic I, Alborzinia H, Can S, Kitanovic A, Onambele LA, Stefanopoulou M, Geldmacher Y, Sheldrick WS, Wolber G, Prokop A, Wölfl S, Ott I.
    J Med Chem; 2010 Dec 23; 53(24):8608-18. PubMed ID: 21082862
    [Abstract] [Full Text] [Related]

  • 9. Coordination of thiosemicarbazones and bis(thiosemicarbazones) to bismuth(III) as a strategy for the design of metal-based antibacterial agents.
    Lessa JA, Reis DC, Da Silva JG, Paradizzi LT, da Silva NF, Carvalho Mde F, Siqueira SA, Beraldo H.
    Chem Biodivers; 2012 Sep 23; 9(9):1955-66. PubMed ID: 22976983
    [Abstract] [Full Text] [Related]

  • 10. Metal complexes with 2-acetylpyridine-N(4)-orthochlorophenylthiosemicarbazone: cytotoxicity and effect on the enzymatic activity of thioredoxin reductase and glutathione reductase.
    Parrilha GL, Ferraz KS, Lessa JA, de Oliveira KN, Rodrigues BL, Ramos JP, Souza-Fagundes EM, Ott I, Beraldo H.
    Eur J Med Chem; 2014 Sep 12; 84():537-44. PubMed ID: 25058344
    [Abstract] [Full Text] [Related]

  • 11. 2-Benzoylpyridine-N(4)-tolyl thiosemicarbazones and their palladium(II) complexes: cytotoxicity against leukemia cells.
    Ferraz KS, Ferandes L, Carrilho D, Pinto MC, Leite Mde F, Souza-Fagundes EM, Speziali NL, Mendes IC, Beraldo H.
    Bioorg Med Chem; 2009 Oct 15; 17(20):7138-44. PubMed ID: 19773176
    [Abstract] [Full Text] [Related]

  • 12. N(4)-tolyl-2-acetylpyridine thiosemicarbazones and their platinum(II,IV) and gold(III) complexes: cytotoxicity against human glioma cells and studies on the mode of action.
    Ferraz KS, Da Silva JG, Costa FM, Mendes BM, Rodrigues BL, dos Santos RG, Beraldo H.
    Biometals; 2013 Oct 15; 26(5):677-91. PubMed ID: 23749148
    [Abstract] [Full Text] [Related]

  • 13. Palladium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones: spectral characterization, structural studies and cytotoxic activity.
    Rebolledo AP, Vieites M, Gambino D, Piro OE, Castellano EE, Zani CL, Souza-Fagundes EM, Teixeira LR, Batista AA, Beraldo H.
    J Inorg Biochem; 2005 Mar 15; 99(3):698-706. PubMed ID: 15708790
    [Abstract] [Full Text] [Related]

  • 14. Cytotoxic activity, albumin and DNA binding of new copper(II) complexes with chalcone-derived thiosemicarbazones.
    Da Silva JG, Recio Despaigne AA, Louro SR, Bandeira CC, Souza-Fagundes EM, Beraldo H.
    Eur J Med Chem; 2013 Jul 15; 65():415-26. PubMed ID: 23747809
    [Abstract] [Full Text] [Related]

  • 15. Platinum(II) and palladium(II) complexes with (N,N') and (C,N,N')- ligands derived from pyrazole as anticancer and antimalarial agents: synthesis, characterization and in vitro activities.
    Quirante J, Ruiz D, Gonzalez A, López C, Cascante M, Cortés R, Messeguer R, Calvis C, Baldomà L, Pascual A, Guérardel Y, Pradines B, Font-Bardía M, Calvet T, Biot C.
    J Inorg Biochem; 2011 Dec 15; 105(12):1720-8. PubMed ID: 22104300
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, structural characterization, and pro-apoptotic activity of 1-indanone thiosemicarbazone platinum(II) and palladium(II) complexes: potential as antileukemic agents.
    Gómez N, Santos D, Vázquez R, Suescun L, Mombrú A, Vermeulen M, Finkielsztein L, Shayo C, Moglioni A, Gambino D, Davio C.
    ChemMedChem; 2011 Aug 01; 6(8):1485-94. PubMed ID: 21608131
    [Abstract] [Full Text] [Related]

  • 17. In vitro antitumour activity of water soluble Cu(I), Ag(I) and Au(I) complexes supported by hydrophilic alkyl phosphine ligands.
    Santini C, Pellei M, Papini G, Morresi B, Galassi R, Ricci S, Tisato F, Porchia M, Rigobello MP, Gandin V, Marzano C.
    J Inorg Biochem; 2011 Feb 01; 105(2):232-40. PubMed ID: 21194623
    [Abstract] [Full Text] [Related]

  • 18. Comparative in vitro evaluation of N-heterocyclic carbene gold(I) complexes of the benzimidazolylidene type.
    Rubbiani R, Can S, Kitanovic I, Alborzinia H, Stefanopoulou M, Kokoschka M, Mönchgesang S, Sheldrick WS, Wölfl S, Ott I.
    J Med Chem; 2011 Dec 22; 54(24):8646-57. PubMed ID: 22039997
    [Abstract] [Full Text] [Related]

  • 19. Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines.
    Graminha AE, Rodrigues C, Batista AA, Teixeira LR, Fagundes ES, Beraldo H.
    Spectrochim Acta A Mol Biomol Spectrosc; 2008 Apr 22; 69(4):1073-6. PubMed ID: 17706455
    [Abstract] [Full Text] [Related]

  • 20. N⁴-Phenyl-substituted 2-acetylpyridine thiosemicarbazones: cytotoxicity against human tumor cells, structure-activity relationship studies and investigation on the mechanism of action.
    Soares MA, Lessa JA, Mendes IC, Da Silva JG, Dos Santos RG, Salum LB, Daghestani H, Andricopulo AD, Day BW, Vogt A, Pesquero JL, Rocha WR, Beraldo H.
    Bioorg Med Chem; 2012 Jun 01; 20(11):3396-409. PubMed ID: 22564383
    [Abstract] [Full Text] [Related]

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