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Journal Abstract Search

266 related items for PubMed ID: 22006862

  • 1. Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study.
    Pandey M, Kaur P, Shukla S, Abbas A, Fu P, Gupta S.
    Mol Carcinog; 2012 Dec; 51(12):952-62. PubMed ID: 22006862
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression.
    Tseng TH, Chien MH, Lin WL, Wen YC, Chow JM, Chen CK, Kuo TC, Lee WJ.
    Environ Toxicol; 2017 Feb; 32(2):434-444. PubMed ID: 26872304
    [Abstract] [Full Text] [Related]

  • 3. Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases.
    Thakur VS, Gupta K, Gupta S.
    Carcinogenesis; 2012 Feb; 33(2):377-84. PubMed ID: 22114073
    [Abstract] [Full Text] [Related]

  • 4. Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer.
    Shukla S, Fu P, Gupta S.
    Apoptosis; 2014 May; 19(5):883-94. PubMed ID: 24563225
    [Abstract] [Full Text] [Related]

  • 5. Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.
    Habold C, Poehlmann A, Bajbouj K, Hartig R, Korkmaz KS, Roessner A, Schneider-Stock R.
    J Cell Mol Med; 2008 Apr; 12(2):607-21. PubMed ID: 18419600
    [Abstract] [Full Text] [Related]

  • 6. Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft.
    Shukla S, Gupta S.
    Mol Cancer Ther; 2006 Apr; 5(4):843-52. PubMed ID: 16648554
    [Abstract] [Full Text] [Related]

  • 7. Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases.
    Thakur VS, Gupta K, Gupta S.
    Int J Oncol; 2012 Jul; 41(1):353-61. PubMed ID: 22552582
    [Abstract] [Full Text] [Related]

  • 8. P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.
    Bajbouj K, Mawrin C, Hartig R, Schulze-Luehrmann J, Wilisch-Neumann A, Roessner A, Schneider-Stock R.
    J Neurooncol; 2012 May; 107(3):503-16. PubMed ID: 22270849
    [Abstract] [Full Text] [Related]

  • 9. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
    Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G.
    J Pharmacol Exp Ther; 2007 Jun; 321(3):953-60. PubMed ID: 17389244
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, characterization, and evaluation of Cd[L-proline]2, a novel histone deacetylase inhibitor that induces epigenetic modification of histone deacetylase isoforms in A549 cells.
    Chidambaram A, Sekar A, S H K, Chidambaram RK, Arunachalam K, G P S, Vilwanathan R.
    Invest New Drugs; 2017 Dec; 35(6):691-705. PubMed ID: 28776290
    [Abstract] [Full Text] [Related]

  • 11. Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells.
    Pal-Bhadra M, Ramaiah MJ, Reddy TL, Krishnan A, Pushpavalli SN, Babu KS, Tiwari AK, Rao JM, Yadav JS, Bhadra U.
    BMC Cancer; 2012 May 16; 12():180. PubMed ID: 22591439
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase.
    Butler LM, Webb Y, Agus DB, Higgins B, Tolentino TR, Kutko MC, LaQuaglia MP, Drobnjak M, Cordon-Cardo C, Scher HI, Breslow R, Richon VM, Rifkind RA, Marks PA.
    Clin Cancer Res; 2001 Apr 16; 7(4):962-70. PubMed ID: 11309347
    [Abstract] [Full Text] [Related]

  • 13. Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma.
    Zhou H, Cai Y, Liu D, Li M, Sha Y, Zhang W, Wang K, Gong J, Tang N, Huang A, Xia J.
    Cell Prolif; 2018 Jun 16; 51(3):e12447. PubMed ID: 29484736
    [Abstract] [Full Text] [Related]

  • 14. Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.
    Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM.
    J Biol Chem; 2006 May 12; 281(19):13548-13558. PubMed ID: 16533812
    [Abstract] [Full Text] [Related]

  • 15. Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.
    Clarke JD, Hsu A, Yu Z, Dashwood RH, Ho E.
    Mol Nutr Food Res; 2011 Jul 12; 55(7):999-1009. PubMed ID: 21374800
    [Abstract] [Full Text] [Related]

  • 16. Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms.
    Gupta K, Thakur VS, Bhaskaran N, Nawab A, Babcook MA, Jackson MW, Gupta S.
    PLoS One; 2012 Jul 12; 7(12):e52572. PubMed ID: 23285096
    [Abstract] [Full Text] [Related]

  • 17. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation.
    Richon VM, Sandhoff TW, Rifkind RA, Marks PA.
    Proc Natl Acad Sci U S A; 2000 Aug 29; 97(18):10014-9. PubMed ID: 10954755
    [Abstract] [Full Text] [Related]

  • 18. Epigenetic regulation of vascular smooth muscle cell proliferation and neointima formation by histone deacetylase inhibition.
    Findeisen HM, Gizard F, Zhao Y, Qing H, Heywood EB, Jones KL, Cohn D, Bruemmer D.
    Arterioscler Thromb Vasc Biol; 2011 Apr 29; 31(4):851-60. PubMed ID: 21233448
    [Abstract] [Full Text] [Related]

  • 19. Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.
    Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S.
    FASEB J; 2005 Dec 29; 19(14):2042-4. PubMed ID: 16230333
    [Abstract] [Full Text] [Related]

  • 20. A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells.
    Patra N, De U, Kim TH, Lee YJ, Ahn MY, Kim ND, Yoon JH, Choi WS, Moon HR, Lee BM, Kim HS.
    Biomed Pharmacother; 2013 Jun 29; 67(5):407-15. PubMed ID: 23583193
    [Abstract] [Full Text] [Related]

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