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556 related items for PubMed ID: 22011623
1. Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma. Gong K, Li W. Free Radic Biol Med; 2011 Dec 15; 51(12):2259-71. PubMed ID: 22011623 [Abstract] [Full Text] [Related]
2. Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma. Liu C, Gong K, Mao X, Li W. Int J Cancer; 2011 Sep 15; 129(6):1519-31. PubMed ID: 21128229 [Abstract] [Full Text] [Related]
3. Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway. Min R, Tong J, Wenjun Y, Wenhu D, Xiaojian Z, Jiacai H, Jian Z, Wantao C, Chenping Z. Phytother Res; 2008 Mar 15; 22(3):407-15. PubMed ID: 18167055 [Abstract] [Full Text] [Related]
4. Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway. Liu B, Jin J, Zhang Z, Zuo L, Jiang M, Xie C. Biochem Cell Biol; 2019 Aug 15; 97(4):397-405. PubMed ID: 30475643 [Abstract] [Full Text] [Related]
5. Down-regulation of phospho-Akt is a major molecular determinant of bortezomib-induced apoptosis in hepatocellular carcinoma cells. Chen KF, Yeh PY, Yeh KH, Lu YS, Huang SY, Cheng AL. Cancer Res; 2008 Aug 15; 68(16):6698-707. PubMed ID: 18701494 [Abstract] [Full Text] [Related]
6. Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms. Chen CY, Liu TZ, Chen CH, Wu CC, Cheng JT, Yiin SJ, Shih MK, Wu MJ, Chern CL. Food Chem Toxicol; 2007 Jul 15; 45(7):1268-76. PubMed ID: 17321026 [Abstract] [Full Text] [Related]
7. [Antitumor effect and mechanism of shikonin derivative SYUNZ-7]. Huang H, Xie BF, Zhu XF, Feng GK, Zhou JM, Wang Y, Wu HQ, Huang ZS, Gu LQ, Liu ZC. Ai Zheng; 2005 Dec 15; 24(12):1453-8. PubMed ID: 16351791 [Abstract] [Full Text] [Related]
8. Synergistic antitumor activity of oridonin and arsenic trioxide on hepatocellular carcinoma cells. Chen G, Wang K, Yang BY, Tang B, Chen JX, Hua ZC. Int J Oncol; 2012 Jan 15; 40(1):139-47. PubMed ID: 21947421 [Abstract] [Full Text] [Related]
9. Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo. Hsu YL, Kuo PL, Tzeng TF, Sung SC, Yen MH, Lin LT, Lin CC. J Gastroenterol Hepatol; 2008 Jul 15; 23(7 Pt 2):e290-9. PubMed ID: 18522681 [Abstract] [Full Text] [Related]
10. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells. Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL. Cancer Lett; 2008 Jan 18; 259(1):82-98. PubMed ID: 18023967 [Abstract] [Full Text] [Related]
11. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma. Gong K, Zhang Z, Chen Y, Shu HB, Li W. Eur J Pharmacol; 2014 Sep 05; 738():142-52. PubMed ID: 24886888 [Abstract] [Full Text] [Related]
12. Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB. Ma Y, Wang J, Liu L, Zhu H, Chen X, Pan S, Sun X, Jiang H. Cancer Lett; 2011 Feb 01; 301(1):75-84. PubMed ID: 21078540 [Abstract] [Full Text] [Related]
13. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis. Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im DS, Kyun ML, Lee K, Song KB, Chung KS. Apoptosis; 2013 Jul 01; 18(7):870-81. PubMed ID: 23546866 [Abstract] [Full Text] [Related]
14. Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism. Lampiasi N, Azzolina A, D'Alessandro N, Umezawa K, McCubrey JA, Montalto G, Cervello M. Mol Pharmacol; 2009 Aug 01; 76(2):290-300. PubMed ID: 19461054 [Abstract] [Full Text] [Related]
15. Shikonin inhibits thyroid cancer cell growth and invasiveness through targeting major signaling pathways. Yang Q, Ji M, Guan H, Shi B, Hou P. J Clin Endocrinol Metab; 2013 Dec 01; 98(12):E1909-17. PubMed ID: 24106286 [Abstract] [Full Text] [Related]
16. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells. Mao X, Yu CR, Li WH, Li WX. Cell Res; 2008 Aug 01; 18(8):879-88. PubMed ID: 18663379 [Abstract] [Full Text] [Related]
17. The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism. Lampiasi N, Azzolina A, Umezawa K, Montalto G, McCubrey JA, Cervello M. Cancer Lett; 2012 Sep 01; 322(1):35-44. PubMed ID: 22343223 [Abstract] [Full Text] [Related]
18. Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice. Wang GY, Lv QH, Dong Q, Xu RZ, Dong QH. J Asian Nat Prod Res; 2009 Sep 01; 11(3):219-28. PubMed ID: 19408145 [Abstract] [Full Text] [Related]
19. DHMEQ, a novel NF-kappaB inhibitor, induces apoptosis and cell-cycle arrest in human hepatoma cells. Nishimura D, Ishikawa H, Matsumoto K, Shibata H, Motoyoshi Y, Fukuta M, Kawashimo H, Goto T, Taura N, Ichikawa T, Hamasaki K, Nakao K, Umezawa K, Eguchi K. Int J Oncol; 2006 Sep 01; 29(3):713-9. PubMed ID: 16865289 [Abstract] [Full Text] [Related]
20. Shikonin inhibits the proliferation and induces the apoptosis of human HepG2 cells. Yingkun N, Lvsong Z, Huimin Y. Can J Physiol Pharmacol; 2010 Dec 01; 88(12):1138-46. PubMed ID: 21164560 [Abstract] [Full Text] [Related] Page: [Next] [New Search]