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Journal Abstract Search


312 related items for PubMed ID: 2201436

  • 1. Evaluation of cysteine adduct formation in rat hemoglobin by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and related compounds.
    Carmella SG, Kagan SS, Spratt TE, Hecht SS.
    Cancer Res; 1990 Sep 01; 50(17):5453-9. PubMed ID: 2201436
    [Abstract] [Full Text] [Related]

  • 2. Formation of hemoglobin adducts upon treatment of F344 rats with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Carmella SG, Hecht SS.
    Cancer Res; 1987 May 15; 47(10):2626-30. PubMed ID: 3567895
    [Abstract] [Full Text] [Related]

  • 3. Two types of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone hemoglobin adducts, from metabolites which migrate into or are formed in red blood cells.
    Murphy SE, Coletta KA.
    Cancer Res; 1993 Feb 15; 53(4):777-83. PubMed ID: 8428358
    [Abstract] [Full Text] [Related]

  • 4. Investigations of metabolic precursors to hemoglobin and DNA adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Peterson LA, Carmella SG, Hecht SS.
    Carcinogenesis; 1990 Aug 15; 11(8):1329-33. PubMed ID: 2387018
    [Abstract] [Full Text] [Related]

  • 5. Dose-response study of DNA and hemoglobin adduct formation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats.
    Murphy SE, Palomino A, Hecht SS, Hoffmann D.
    Cancer Res; 1990 Sep 01; 50(17):5446-52. PubMed ID: 2386949
    [Abstract] [Full Text] [Related]

  • 6. Evidence that a hemoglobin adduct of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a 4-(3-pyridyl)-4-oxobutyl carboxylic acid ester.
    Carmella SG, Kagan SS, Hecht SS.
    Chem Res Toxicol; 1992 Sep 01; 5(1):76-80. PubMed ID: 1581541
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  • 9. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.
    Wang M, Cheng G, Sturla SJ, Shi Y, McIntee EJ, Villalta PW, Upadhyaya P, Hecht SS.
    Chem Res Toxicol; 2003 May 01; 16(5):616-26. PubMed ID: 12755591
    [Abstract] [Full Text] [Related]

  • 10. Hemoglobin adducts as biomarkers of exposure to and metabolic activation of carcinogenic tobacco-specific nitrosamines.
    Hecht SS, Carmella SG, Murphy SE.
    Biomed Environ Sci; 1991 Jun 01; 4(1-2):93-103. PubMed ID: 1910605
    [Abstract] [Full Text] [Related]

  • 11. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
    Murphy SE, Heiblum R, Trushin N.
    Cancer Res; 1990 Aug 01; 50(15):4685-91. PubMed ID: 2369743
    [Abstract] [Full Text] [Related]

  • 12. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW.
    Chem Res Toxicol; 2005 Jun 01; 18(6):1048-55. PubMed ID: 15962940
    [Abstract] [Full Text] [Related]

  • 13. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM, Kenney PM, Peterson LA.
    Chem Res Toxicol; 2003 Jan 01; 16(1):1-6. PubMed ID: 12693024
    [Abstract] [Full Text] [Related]

  • 14. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P, Kalscheuer S, Hochalter JB, Villalta PW, Hecht SS.
    Chem Res Toxicol; 2008 Jul 01; 21(7):1468-76. PubMed ID: 18570389
    [Abstract] [Full Text] [Related]

  • 15. Tobacco-specific nitrosamine adducts: studies in laboratory animals and humans.
    Hecht SS, Carmella SG, Foiles PG, Murphy SE, Peterson LA.
    Environ Health Perspect; 1993 Mar 01; 99():57-63. PubMed ID: 8319660
    [Abstract] [Full Text] [Related]

  • 16. Nucleophilic reactions between thiols and a tobacco specific nitrosamine metabolite, 4-hydroxy-1-(3-pyridyl)-1-butanone.
    Peterson LA, Predecki DP, Thomson NM, Villalta PW, Donaldson EE.
    Chem Res Toxicol; 2003 May 01; 16(5):661-7. PubMed ID: 12755596
    [Abstract] [Full Text] [Related]

  • 17. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 01; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 18. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
    Hecht SS, Villalta PW, Sturla SJ, Cheng G, Yu N, Upadhyaya P, Wang M.
    Chem Res Toxicol; 2004 May 01; 17(5):588-97. PubMed ID: 15144215
    [Abstract] [Full Text] [Related]

  • 19. DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Hecht SS, Trushin N.
    Carcinogenesis; 1988 Sep 01; 9(9):1665-8. PubMed ID: 3409470
    [Abstract] [Full Text] [Related]

  • 20. Effects of phenobarbital and 3-methylcholanthrene induction on the formation of three glucuronide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, NNK.
    Murphy SE, Nunes MG, Hatala MA.
    Chem Biol Interact; 1997 Mar 14; 103(3):153-66. PubMed ID: 9134006
    [Abstract] [Full Text] [Related]


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