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PUBMED FOR HANDHELDS

Journal Abstract Search


110 related items for PubMed ID: 22014749

  • 1. Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors.
    He XY, Zou P, Qiu J, Hou L, Jiang S, Liu S, Xie L.
    Bioorg Med Chem; 2011 Nov 15; 19(22):6726-34. PubMed ID: 22014749
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  • 2. Small molecule fusion inhibitors: design, synthesis and biological evaluation of (Z)-3-(5-(3-benzyl-4-oxo-2-thioxothiazolidinylidene)methyl)-N-(3-carboxy-4-hydroxy)phenyl-2,5-dimethylpyrroles and related derivatives targeting HIV-1 gp41.
    He XY, Lu L, Qiu J, Zou P, Yu F, Jiang XK, Li L, Jiang S, Liu S, Xie L.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7539-48. PubMed ID: 23673219
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  • 3. Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41.
    Jiang S, Tala SR, Lu H, Zou P, Avan I, Ibrahim TS, Abo-Dya NE, Abdelmajeid A, Debnath AK, Katritzky AR.
    Bioorg Med Chem Lett; 2011 Nov 15; 21(22):6895-8. PubMed ID: 21978673
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  • 4. Molecular modeling studies of N-substituted pyrrole derivatives--potential HIV-1 gp41 inhibitors.
    Teixeira C, Barbault F, Rebehmed J, Liu K, Xie L, Lu H, Jiang S, Fan B, Maurel F.
    Bioorg Med Chem; 2008 Mar 15; 16(6):3039-48. PubMed ID: 18226912
    [Abstract] [Full Text] [Related]

  • 5. Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation.
    Liu B, Joseph RW, Dorsey BD, Schiksnis RA, Northrop K, Bukhtiyarova M, Springman EB.
    Bioorg Med Chem Lett; 2009 Oct 01; 19(19):5693-7. PubMed ID: 19699090
    [Abstract] [Full Text] [Related]

  • 6. Computer-aided design, synthesis, and biological activity evaluation of potent fusion inhibitors targeting HIV-1 gp41.
    Tan JJ, Zhang B, Cong XJ, Yang LF, Liu B, Kong R, Kui ZY, Wang CX, Hu LM.
    Med Chem; 2011 Jul 01; 7(4):309-16. PubMed ID: 21568877
    [Abstract] [Full Text] [Related]

  • 7. Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.
    Wang Y, Lu H, Zhu Q, Jiang S, Liao Y.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):189-92. PubMed ID: 19932616
    [Abstract] [Full Text] [Related]

  • 8. Structure-based identification of small molecule antiviral compounds targeted to the gp41 core structure of the human immunodeficiency virus type 1.
    Debnath AK, Radigan L, Jiang S.
    J Med Chem; 1999 Aug 26; 42(17):3203-9. PubMed ID: 10464007
    [Abstract] [Full Text] [Related]

  • 9. Development of HIV entry inhibitors targeted to the coiled-coil regions of gp41.
    Jiang S, Debnath AK.
    Biochem Biophys Res Commun; 2000 Mar 24; 269(3):641-6. PubMed ID: 10720469
    [Abstract] [Full Text] [Related]

  • 10. Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase.
    Verschueren WG, Dierynck I, Amssoms KI, Hu L, Boonants PM, Pille GM, Daeyaert FF, Hertogs K, Surleraux DL, Wigerinck PB.
    J Med Chem; 2005 Mar 24; 48(6):1930-40. PubMed ID: 15771437
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  • 19. Tannin inhibits HIV-1 entry by targeting gp41.
    Lü L, Liu SW, Jiang SB, Wu SG.
    Acta Pharmacol Sin; 2004 Feb 24; 25(2):213-8. PubMed ID: 14769212
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