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PUBMED FOR HANDHELDS

Journal Abstract Search


376 related items for PubMed ID: 22014996

  • 1. Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: in vitro evaluation, cell cycle analysis and QSAR studies.
    Abreu RM, Ferreira IC, Calhelha RC, Lima RT, Vasconcelos MH, Adega F, Chaves R, Queiroz MJ.
    Eur J Med Chem; 2011 Dec; 46(12):5800-6. PubMed ID: 22014996
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-activity relationships, effects on the cell cycle and apoptosis.
    Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH.
    Eur J Med Chem; 2011 Jan; 46(1):236-40. PubMed ID: 21138784
    [Abstract] [Full Text] [Related]

  • 3. New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death.
    Queiroz MJ, Peixoto D, Calhelha RC, Soares P, Dos Santos T, Lima RT, Campos JF, Abreu RM, Ferreira IC, Vasconcelos MH.
    Eur J Med Chem; 2013 Nov; 69():855-62. PubMed ID: 24121236
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  • 5. Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: synthesis and antitumoral activities.
    Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.
    Eur J Med Chem; 2010 Dec; 45(12):5732-8. PubMed ID: 20934235
    [Abstract] [Full Text] [Related]

  • 6. Molecular mechanism of hepatocellular carcinoma-specific antitumor activity of the novel thienopyridine derivative TP58.
    Zhou R, Huang WJ, Guo ZY, Li L, Zeng XR, Deng YQ, Hu FY, Tong AP, Yang L, Yang JL.
    Oncol Rep; 2012 Jul; 28(1):225-31. PubMed ID: 22552608
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  • 7. Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines.
    Willemann C, Grünert R, Bednarski PJ, Troschütz R.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4406-19. PubMed ID: 19481463
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  • 10. Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo.
    Xu YZ, Zheng RL, Zhou Y, Peng F, Lin HJ, Bu Q, Mao YQ, Yu LT, Yang L, Yang SY, Zhao YL.
    Cancer Lett; 2011 Dec 26; 313(1):44-53. PubMed ID: 21944661
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  • 12. Hydrazones of 2-aryl-quinoline-4-carboxylic acid hydrazides: synthesis and preliminary evaluation as antimicrobial agents.
    Metwally KA, Abdel-Aziz LM, Lashine el-SM, Husseiny MI, Badawy RH.
    Bioorg Med Chem; 2006 Dec 15; 14(24):8675-82. PubMed ID: 16949294
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  • 14. Silibinin efficacy against human hepatocellular carcinoma.
    Varghese L, Agarwal C, Tyagi A, Singh RP, Agarwal R.
    Clin Cancer Res; 2005 Dec 01; 11(23):8441-8. PubMed ID: 16322307
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  • 15. Design, synthesis and biological evaluation of pyridine acyl sulfonamide derivatives as novel COX-2 inhibitors.
    Lu X, Zhang H, Li X, Chen G, Li QS, Luo Y, Ruan BF, Chen XW, Zhu HL.
    Bioorg Med Chem; 2011 Nov 15; 19(22):6827-32. PubMed ID: 22000948
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  • 17. Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic Membrane (CAM) with a Triple Negative Breast Cancer Cell Line.
    Silva BR, Rebelo R, Rodrigues JM, Xavier CPR, Vasconcelos MH, Queiroz MRP.
    Molecules; 2021 Mar 13; 26(6):. PubMed ID: 33805741
    [Abstract] [Full Text] [Related]

  • 18. Anti-cancer effects of a novel compound HS-113 on cell growth, apoptosis, and angiogenesis in human hepatocellular carcinoma cells.
    Choi MJ, Jung KH, Kim D, Lee H, Zheng HM, Park BH, Hong SW, Kim MH, Hong S, Hong SS.
    Cancer Lett; 2011 Jul 28; 306(2):190-6. PubMed ID: 21463918
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  • 20. Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest.
    Lam TL, Wong GK, Chong HC, Cheng PN, Choi SC, Chow TL, Kwok SY, Poon RT, Wheatley DN, Lo WH, Leung YC.
    Cancer Lett; 2009 May 08; 277(1):91-100. PubMed ID: 19138817
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