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Journal Abstract Search

170 related items for PubMed ID: 22015678

  • 1.
    ; . PubMed ID:
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  • 2. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
    [Abstract] [Full Text] [Related]

  • 3. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 01; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

  • 4. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ, Yu YG, Hahn HG, Choi JD, Yoon MY.
    FEBS Lett; 2005 Aug 29; 579(21):4903-10. PubMed ID: 16111681
    [Abstract] [Full Text] [Related]

  • 5. Identification and characterization of inhibitors of Haemophilus influenzae acetohydroxyacid synthase.
    Gedi V, Moon JY, Lim WM, Lee MY, Lee SC, Koo BS, Govindwar S, Yoon MY.
    Enzyme Microb Technol; 2011 Jun 10; 49(1):1-5. PubMed ID: 22112263
    [Abstract] [Full Text] [Related]

  • 6. Development of potent chemical antituberculosis agents targeting Mycobacterium tuberculosis acetohydroxyacid synthase.
    Jung IP, Ha NR, Lee SC, Ryoo SW, Yoon MY.
    Int J Antimicrob Agents; 2016 Sep 10; 48(3):247-58. PubMed ID: 27451857
    [Abstract] [Full Text] [Related]

  • 7. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY.
    Biosci Biotechnol Biochem; 2010 Sep 10; 74(11):2281-6. PubMed ID: 21071847
    [Abstract] [Full Text] [Related]

  • 8. Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Gedi V, Lee SC, Koh SH, Yoon MY.
    Enzyme Microb Technol; 2013 Sep 10; 53(4):243-9. PubMed ID: 23931689
    [Abstract] [Full Text] [Related]

  • 9. Acetohydroxyacid synthase: a target for antimicrobial drug discovery.
    Pue N, Guddat LW.
    Curr Pharm Des; 2014 Sep 10; 20(5):740-53. PubMed ID: 23688082
    [Abstract] [Full Text] [Related]

  • 10. Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Moon JY, Lee SC, Ryoo SW, Yoon MY.
    Biochim Biophys Acta; 2015 Oct 10; 1854(10 Pt A):1338-50. PubMed ID: 25988243
    [Abstract] [Full Text] [Related]

  • 11. Bacterial acetohydroxyacid synthase and its inhibitors--a summary of their structure, biological activity and current status.
    Gedi V, Yoon MY.
    FEBS J; 2012 Mar 10; 279(6):946-63. PubMed ID: 22284339
    [Abstract] [Full Text] [Related]

  • 12. Identification of the regulatory subunit of Arabidopsis thaliana acetohydroxyacid synthase and reconstitution with its catalytic subunit.
    Lee YT, Duggleby RG.
    Biochemistry; 2001 Jun 12; 40(23):6836-44. PubMed ID: 11389597
    [Abstract] [Full Text] [Related]

  • 13. Binding and activation of thiamin diphosphate in acetohydroxyacid synthase.
    Bar-Ilan A, Balan V, Tittmann K, Golbik R, Vyazmensky M, Hübner G, Barak Z, Chipman DM.
    Biochemistry; 2001 Oct 02; 40(39):11946-54. PubMed ID: 11570896
    [Abstract] [Full Text] [Related]

  • 14. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM.
    FEBS J; 2012 Jun 02; 279(11):1967-79. PubMed ID: 22443469
    [Abstract] [Full Text] [Related]

  • 15. Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors.
    Pang SS, Duggleby RG, Guddat LW.
    J Mol Biol; 2002 Mar 22; 317(2):249-62. PubMed ID: 11902841
    [Abstract] [Full Text] [Related]

  • 16. Mechanisms of bacterial acetohydroxyacid synthase (AHAS) and specific inhibitors of Mycobacterium tuberculosis AHAS as potential drug candidates against tuberculosis.
    Gokhale K, Tilak B.
    Curr Drug Targets; 2015 Mar 22; 16(7):689-99. PubMed ID: 25882218
    [Abstract] [Full Text] [Related]

  • 17. Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase II.
    Vyazmensky M, Steinmetz A, Meyer D, Golbik R, Barak Z, Tittmann K, Chipman DM.
    Biochemistry; 2011 Apr 19; 50(15):3250-60. PubMed ID: 21370850
    [Abstract] [Full Text] [Related]

  • 18. Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme.
    Tittmann K, Schröder K, Golbik R, McCourt J, Kaplun A, Duggleby RG, Barak Z, Chipman DM, Hübner G.
    Biochemistry; 2004 Jul 13; 43(27):8652-61. PubMed ID: 15236573
    [Abstract] [Full Text] [Related]

  • 19. Evaluation of substituted triazol-1-yl-pyrimidines as inhibitors of Bacillus anthracis acetohydroxyacid synthase.
    Gedi V, Jayaraman K, Kalme S, Park HY, Park HC, La IJ, Hahn HG, Yoon MY.
    Biochim Biophys Acta; 2010 Jun 13; 1804(6):1369-75. PubMed ID: 20170757
    [Abstract] [Full Text] [Related]

  • 20. Expression, purification and characterization of Arabidopsis thaliana acetohydroxyacid synthase.
    Chang AK, Duggleby RG.
    Biochem J; 1997 Oct 01; 327 ( Pt 1)(Pt 1):161-9. PubMed ID: 9355748
    [Abstract] [Full Text] [Related]

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