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Journal Abstract Search


135 related items for PubMed ID: 22015773

  • 1. Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia.
    Stumpel DJ, Schneider P, Seslija L, Osaki H, Williams O, Pieters R, Stam RW.
    Leukemia; 2012 Apr; 26(4):682-92. PubMed ID: 22015773
    [Abstract] [Full Text] [Related]

  • 2. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
    Gessner A, Thomas M, Castro PG, Büchler L, Scholz A, Brümmendorf TH, Soria NM, Vormoor J, Greil J, Heidenreich O.
    Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
    [Abstract] [Full Text] [Related]

  • 3. Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options.
    Stumpel DJ, Schneider P, van Roon EH, Boer JM, de Lorenzo P, Valsecchi MG, de Menezes RX, Pieters R, Stam RW.
    Blood; 2009 Dec 24; 114(27):5490-8. PubMed ID: 19855078
    [Abstract] [Full Text] [Related]

  • 4. A Novel t(4;11)(q21;q23) MLL-AF4 fusion transcript in infant leukemia.
    Abdelhaleem M, Yi Q, Beimnet K, Grant R.
    Am J Hematol; 2007 Mar 24; 82(3):247. PubMed ID: 16924642
    [No Abstract] [Full Text] [Related]

  • 5. Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression.
    Dou L, Zheng D, Li J, Li Y, Gao L, Wang L, Yu L.
    Oncogene; 2012 Jan 26; 31(4):507-17. PubMed ID: 21706045
    [Abstract] [Full Text] [Related]

  • 6. A novel infant acute lymphoblastic leukemia cell line with MLL-AF5q31 fusion transcript.
    Imamura T, Morimoto A, Ikushima S, Kakazu N, Hada S, Tabata Y, Yagi T, Inaba T, Hibi S, Sugimoto T, Imashuku S.
    Leukemia; 2002 Nov 26; 16(11):2302-8. PubMed ID: 12399976
    [Abstract] [Full Text] [Related]

  • 7. DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4.
    Bardini M, Spinelli R, Bungaro S, Mangano E, Corral L, Cifola I, Fazio G, Giordan M, Basso G, De Rossi G, Biondi A, Battaglia C, Cazzaniga G.
    Leukemia; 2010 Jan 26; 24(1):169-76. PubMed ID: 19907438
    [Abstract] [Full Text] [Related]

  • 8. Molecular findings in childhood leukemia in Brazil: high frequency of MLL-ENL Fusion/t(11;19) in infant leukemia.
    Marques EA, Neves L, Fonseca TC, Lins MM, Pedrosa F, Lucena-Silva N.
    J Pediatr Hematol Oncol; 2011 Aug 26; 33(6):470-4. PubMed ID: 21436736
    [Abstract] [Full Text] [Related]

  • 9. Genomic analysis of a four-way t(4;11;22;10) associated with MLL-AF4 in an adult acute lymphoblastic leukemia.
    Cho SY, Park TS, Oh SH, Cho EH, Oh D, Huh JY, Marschalek R, Meyer C.
    Ann Hematol; 2012 Jun 26; 91(6):977-9. PubMed ID: 22086294
    [No Abstract] [Full Text] [Related]

  • 10. Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.
    Driessen EM, van Roon EH, Spijkers-Hagelstein JA, Schneider P, de Lorenzo P, Valsecchi MG, Pieters R, Stam RW.
    Haematologica; 2013 Jun 26; 98(6):937-44. PubMed ID: 23403319
    [Abstract] [Full Text] [Related]

  • 11. Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.
    Campo Dell'Orto M, Banelli B, Giarin E, Accordi B, Trentin L, Romani M, te Kronnie G, Basso G.
    Oncol Rep; 2007 Aug 26; 18(2):417-23. PubMed ID: 17611665
    [Abstract] [Full Text] [Related]

  • 12. Dense methylation of types 1 and 2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.
    Ikawa Y, Sugimoto N, Koizumi S, Yachie A, Saikawa Y.
    J Pediatr Hematol Oncol; 2010 Jan 26; 32(1):4-10. PubMed ID: 20051780
    [Abstract] [Full Text] [Related]

  • 13. Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale.
    Stumpel DJ, Schotte D, Lange-Turenhout EA, Schneider P, Seslija L, de Menezes RX, Marquez VE, Pieters R, den Boer ML, Stam RW.
    Leukemia; 2011 Mar 26; 25(3):429-39. PubMed ID: 21116279
    [Abstract] [Full Text] [Related]

  • 14. Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement.
    Bueno C, Montes R, Catalina P, Rodríguez R, Menendez P.
    Leukemia; 2011 Mar 26; 25(3):400-10. PubMed ID: 21135858
    [Abstract] [Full Text] [Related]

  • 15. MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia.
    Panagopoulos I, Lilljebjörn H, Strömbeck B, Hjorth L, Olofsson T, Johansson B.
    Haematologica; 2006 Sep 26; 91(9):1287-8. PubMed ID: 16956839
    [Abstract] [Full Text] [Related]

  • 16. Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.
    van der Linden MH, Seslija L, Schneider P, Driessen EM, Castro PG, Stumpel DJ, van Roon E, de Boer J, Williams O, Pieters R, Stam RW.
    PLoS One; 2015 Sep 26; 10(3):e0120326. PubMed ID: 25793396
    [Abstract] [Full Text] [Related]

  • 17. Leukemia in infants.
    Felix CA, Lange BJ.
    Oncologist; 1999 Sep 26; 4(3):225-40. PubMed ID: 10394590
    [Abstract] [Full Text] [Related]

  • 18. The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia.
    Dobbins SE, Sherborne AL, Ma YP, Bardini M, Biondi A, Cazzaniga G, Lloyd A, Chubb D, Greaves MF, Houlston RS.
    Genes Chromosomes Cancer; 2013 Oct 26; 52(10):954-60. PubMed ID: 23893660
    [Abstract] [Full Text] [Related]

  • 19. Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.
    Stumpel DJ, Schneider P, van Roon EH, Pieters R, Stam RW.
    Eur J Cancer; 2013 Jan 26; 49(1):175-84. PubMed ID: 22921182
    [Abstract] [Full Text] [Related]

  • 20. Multiplex reverse transcription-polymerase chain reaction as diagnostic molecular screening of 4 common fusion chimeric genes in Taiwanese children with acute lymphoblastic leukemia.
    Yang YL, Lin SR, Chen JS, Hsiao CC, Lin KH, Sheen JM, Cheng CN, Wu KH, Lin SW, Yu SL, Chen HY, Lu MY, Chang HH, Yen CT, Lin JF, Su YH, Li YP, Lin CY, Jou ST, Lin DT.
    J Pediatr Hematol Oncol; 2010 Nov 26; 32(8):e323-30. PubMed ID: 20930648
    [Abstract] [Full Text] [Related]


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