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389 related items for PubMed ID: 22021336

  • 1. The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury.
    Funke M, Zhao Z, Xu Y, Chun J, Tager AM.
    Am J Respir Cell Mol Biol; 2012 Mar; 46(3):355-64. PubMed ID: 22021336
    [Abstract] [Full Text] [Related]

  • 2. Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.
    Huang LS, Fu P, Patel P, Harijith A, Sun T, Zhao Y, Garcia JG, Chun J, Natarajan V.
    Am J Respir Cell Mol Biol; 2013 Dec; 49(6):912-22. PubMed ID: 23808384
    [Abstract] [Full Text] [Related]

  • 3. Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.
    Sakai N, Chun J, Duffield JS, Lagares D, Wada T, Luster AD, Tager AM.
    Kidney Int; 2017 Mar; 91(3):628-641. PubMed ID: 27927603
    [Abstract] [Full Text] [Related]

  • 4. The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
    Tager AM, LaCamera P, Shea BS, Campanella GS, Selman M, Zhao Z, Polosukhin V, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, Luster AD.
    Nat Med; 2008 Jan; 14(1):45-54. PubMed ID: 18066075
    [Abstract] [Full Text] [Related]

  • 5. Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.
    Black KE, Berdyshev E, Bain G, Castelino FV, Shea BS, Probst CK, Fontaine BA, Bronova I, Goulet L, Lagares D, Ahluwalia N, Knipe RS, Natarajan V, Tager AM.
    FASEB J; 2016 Jun; 30(6):2435-50. PubMed ID: 27006447
    [Abstract] [Full Text] [Related]

  • 6. Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.
    He D, Su Y, Usatyuk PV, Spannhake EW, Kogut P, Solway J, Natarajan V, Zhao Y.
    J Biol Chem; 2009 Sep 04; 284(36):24123-32. PubMed ID: 19586906
    [Abstract] [Full Text] [Related]

  • 7. Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma.
    Zhao Y, Tong J, He D, Pendyala S, Evgeny B, Chun J, Sperling AI, Natarajan V.
    Respir Res; 2009 Nov 20; 10(1):114. PubMed ID: 19930563
    [Abstract] [Full Text] [Related]

  • 8. A blocking peptide stabilizes lysophosphatidic acid receptor 1 and promotes lysophosphatidic acid-induced cellular responses.
    Taleb SJ, Wei J, Mialki RK, Dong S, Li Y, Zhao J, Zhao Y.
    J Cell Biochem; 2021 Aug 20; 122(8):827-834. PubMed ID: 33847006
    [Abstract] [Full Text] [Related]

  • 9. Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.
    Shea BS, Tager AM.
    Proc Am Thorac Soc; 2012 Jul 20; 9(3):102-10. PubMed ID: 22802282
    [Abstract] [Full Text] [Related]

  • 10. Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts.
    Tang N, Zhao Y, Feng R, Liu Y, Wang S, Wei W, Ding Q, An MS, Wen J, Li L.
    J Cell Mol Med; 2014 Jan 20; 18(1):156-69. PubMed ID: 24251962
    [Abstract] [Full Text] [Related]

  • 11. Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization.
    Funke M, Knudsen L, Lagares D, Ebener S, Probst CK, Fontaine BA, Franklin A, Kellner M, Kühnel M, Matthieu S, Grothausmann R, Chun J, Roberts JD, Ochs M, Tager AM.
    Am J Respir Cell Mol Biol; 2016 Jul 20; 55(1):105-16. PubMed ID: 27082727
    [Abstract] [Full Text] [Related]

  • 12. A novel, orally active LPA(1) receptor antagonist inhibits lung fibrosis in the mouse bleomycin model.
    Swaney JS, Chapman C, Correa LD, Stebbins KJ, Bundey RA, Prodanovich PC, Fagan P, Baccei CS, Santini AM, Hutchinson JH, Seiders TJ, Parr TA, Prasit P, Evans JF, Lorrain DS.
    Br J Pharmacol; 2010 Aug 20; 160(7):1699-713. PubMed ID: 20649573
    [Abstract] [Full Text] [Related]

  • 13. TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.
    Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE.
    Am J Physiol Lung Cell Mol Physiol; 2011 Jun 20; 300(6):L887-97. PubMed ID: 21441353
    [Abstract] [Full Text] [Related]

  • 14. Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin.
    Guzy RD, Stoilov I, Elton TJ, Mecham RP, Ornitz DM.
    Am J Respir Cell Mol Biol; 2015 Jan 20; 52(1):116-28. PubMed ID: 24988442
    [Abstract] [Full Text] [Related]

  • 15. MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis.
    Boehme SA, Franz-Bacon K, DiTirro DN, Ly TW, Bacon KB.
    PLoS One; 2016 Jan 20; 11(5):e0154874. PubMed ID: 27144281
    [Abstract] [Full Text] [Related]

  • 16. Essential role of stem cell factor-c-Kit signalling pathway in bleomycin-induced pulmonary fibrosis.
    Ding L, Dolgachev V, Wu Z, Liu T, Nakashima T, Wu Z, Ullenbruch M, Lukacs NW, Chen Z, Phan SH.
    J Pathol; 2013 Jun 20; 230(2):205-14. PubMed ID: 23401096
    [Abstract] [Full Text] [Related]

  • 17. Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.
    Valero-Jiménez A, Zúñiga J, Cisneros J, Becerril C, Salgado A, Checa M, Buendía-Roldán I, Mendoza-Milla C, Gaxiola M, Pardo A, Selman M.
    PLoS One; 2018 Jun 20; 13(3):e0192963. PubMed ID: 29529050
    [Abstract] [Full Text] [Related]

  • 18. Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs.
    Marudamuthu AS, Shetty SK, Bhandary YP, Karandashova S, Thompson M, Sathish V, Florova G, Hogan TB, Pabelick CM, Prakash YS, Tsukasaki Y, Fu J, Ikebe M, Idell S, Shetty S.
    J Biol Chem; 2015 Apr 10; 290(15):9428-41. PubMed ID: 25648892
    [Abstract] [Full Text] [Related]

  • 19. Hypoxia Promotes Invadosome Formation by Lung Fibroblasts.
    Lebel M, Cliche DO, Charbonneau M, Brochu-Gaudreau K, Adam D, Brochiero E, Dubois CM, Cantin AM.
    Cells; 2024 Jul 06; 13(13):. PubMed ID: 38995003
    [Abstract] [Full Text] [Related]

  • 20. Characterization of lung stem cell niches in a mouse model of bleomycin-induced fibrosis.
    Banerjee ER, Henderson WR.
    Stem Cell Res Ther; 2012 May 29; 3(3):21. PubMed ID: 22643035
    [Abstract] [Full Text] [Related]

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