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Journal Abstract Search

146 related items for PubMed ID: 22031626

  • 1. Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.
    Kimoto E, Walsky R, Zhang H, Bi YA, Whalen KM, Yang YS, Linder C, Xiao Y, Iseki K, Fenner KS, El-Kattan AF, Lai Y.
    Drug Metab Dispos; 2012 Feb; 40(2):407-11. PubMed ID: 22031626
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  • 2. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
    Kotani N, Maeda K, Watanabe T, Hiramatsu M, Gong LK, Bi YA, Takezawa T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Sep; 39(9):1503-10. PubMed ID: 21673128
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  • 8. Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes.
    Feidt DM, Klein K, Hofmann U, Riedmaier S, Knobeloch D, Thasler WE, Weiss TS, Schwab M, Zanger UM.
    Drug Metab Dispos; 2010 Sep; 38(9):1589-97. PubMed ID: 20551241
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  • 9. In vitro characterization of the metabolic pathways and cytochrome P450 inhibition and induction potential of BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor.
    Hong H, Su H, Ma L, Yao M, Iyer RA, Humphreys WG, Christopher LJ.
    Drug Metab Dispos; 2011 Sep; 39(9):1658-67. PubMed ID: 21673131
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  • 10. Analysis of the Metabolic Pathway of Bosentan and of the Cytotoxicity of Bosentan Metabolites Based on a Quantitative Modeling of Metabolism and Transport in Sandwich-Cultured Human Hepatocytes.
    Matsunaga N, Kaneko N, Staub AY, Nakanishi T, Nunoya K, Imawaka H, Tamai I.
    Drug Metab Dispos; 2016 Jan; 44(1):16-27. PubMed ID: 26502773
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  • 15. Characterization of digoxin uptake in sandwich-cultured human hepatocytes.
    Kimoto E, Chupka J, Xiao Y, Bi YA, Duignan DB.
    Drug Metab Dispos; 2011 Jan; 39(1):47-53. PubMed ID: 20926619
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  • 16. Involvement of multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes in the in vitro metabolism of muraglitazar.
    Zhang D, Wang L, Chandrasena G, Ma L, Zhu M, Zhang H, Davis CD, Humphreys WG.
    Drug Metab Dispos; 2007 Jan; 35(1):139-49. PubMed ID: 17062778
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  • 17. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
    Prueksaritanont T, Gorham LM, Ma B, Liu L, Yu X, Zhao JJ, Slaughter DE, Arison BH, Vyas KP.
    Drug Metab Dispos; 1997 Oct; 25(10):1191-9. PubMed ID: 9321523
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  • 18. Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.
    Tsunoda SM, Velez RL, von Moltke LL, Greenblatt DJ.
    Clin Pharmacol Ther; 1999 Nov; 66(5):461-71. PubMed ID: 10579473
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  • 19. Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes.
    Kim KA, Park JY.
    Drug Metab Dispos; 2003 Sep; 31(9):1090-2. PubMed ID: 12920163
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  • 20. Utility of intersystem extrapolation factors in early reaction phenotyping and the quantitative extrapolation of human liver microsomal intrinsic clearance using recombinant cytochromes P450.
    Chen Y, Liu L, Nguyen K, Fretland AJ.
    Drug Metab Dispos; 2011 Mar; 39(3):373-82. PubMed ID: 21148079
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