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Journal Abstract Search

394 related items for PubMed ID: 22038946

  • 1. Biology-oriented synthesis.
    Wetzel S, Bon RS, Kumar K, Waldmann H.
    Angew Chem Int Ed Engl; 2011 Nov 11; 50(46):10800-26. PubMed ID: 22038946
    [Abstract] [Full Text] [Related]

  • 2. Bioactivity-guided navigation of chemical space.
    Bon RS, Waldmann H.
    Acc Chem Res; 2010 Aug 17; 43(8):1103-14. PubMed ID: 20481515
    [Abstract] [Full Text] [Related]

  • 3. Charting, navigating, and populating natural product chemical space for drug discovery.
    Lachance H, Wetzel S, Kumar K, Waldmann H.
    J Med Chem; 2012 Jul 12; 55(13):5989-6001. PubMed ID: 22537178
    [Abstract] [Full Text] [Related]

  • 4. Biology-oriented synthesis: harnessing the power of evolution.
    van Hattum H, Waldmann H.
    J Am Chem Soc; 2014 Aug 27; 136(34):11853-9. PubMed ID: 25074019
    [Abstract] [Full Text] [Related]

  • 5. Principles, implementation, and application of biology-oriented synthesis (BIOS).
    Wilk W, Zimmermann TJ, Kaiser M, Waldmann H.
    Biol Chem; 2010 May 27; 391(5):491-7. PubMed ID: 20030592
    [Abstract] [Full Text] [Related]

  • 6. Expanding the medicinally relevant chemical space with compound libraries.
    López-Vallejo F, Giulianotti MA, Houghten RA, Medina-Franco JL.
    Drug Discov Today; 2012 Jul 27; 17(13-14):718-26. PubMed ID: 22515962
    [Abstract] [Full Text] [Related]

  • 7. Probing the bioactivity-relevant chemical space of robust reactions and common molecular building blocks.
    Hartenfeller M, Eberle M, Meier P, Nieto-Oberhuber C, Altmann KH, Schneider G, Jacoby E, Renner S.
    J Chem Inf Model; 2012 May 25; 52(5):1167-78. PubMed ID: 22512717
    [Abstract] [Full Text] [Related]

  • 8. Design of compound libraries based on natural product scaffolds and protein structure similarity clustering (PSSC).
    Balamurugan R, Dekker FJ, Waldmann H.
    Mol Biosyst; 2005 May 25; 1(1):36-45. PubMed ID: 16880961
    [Abstract] [Full Text] [Related]

  • 9. Exploring and exploiting biologically relevant chemical space.
    Eberhardt L, Kumar K, Waldmann H.
    Curr Drug Targets; 2011 Oct 25; 12(11):1531-46. PubMed ID: 21561426
    [Abstract] [Full Text] [Related]

  • 10. Diversity-oriented synthesis; a spectrum of approaches and results.
    Spandl RJ, Bender A, Spring DR.
    Org Biomol Chem; 2008 Apr 07; 6(7):1149-58. PubMed ID: 18362950
    [Abstract] [Full Text] [Related]

  • 11. Identification of inhibitors for mycobacterial protein tyrosine phosphatase B (MptpB) by biology-oriented synthesis (BIOS).
    Corrêa IR, Nören-Müller A, Ambrosi HD, Jakupovic S, Saxena K, Schwalbe H, Kaiser M, Waldmann H.
    Chem Asian J; 2007 Sep 03; 2(9):1109-26. PubMed ID: 17685373
    [Abstract] [Full Text] [Related]

  • 12. Molecular scaffold analysis of natural products databases in the public domain.
    Yongye AB, Waddell J, Medina-Franco JL.
    Chem Biol Drug Des; 2012 Nov 03; 80(5):717-24. PubMed ID: 22863071
    [Abstract] [Full Text] [Related]

  • 13. Gamma-pyrone natural products--a privileged compound class provided by nature.
    Wilk W, Waldmann H, Kaiser M.
    Bioorg Med Chem; 2009 Mar 15; 17(6):2304-9. PubMed ID: 19042133
    [Abstract] [Full Text] [Related]

  • 14. Mining for bioactive scaffolds with scaffold networks: improved compound set enrichment from primary screening data.
    Varin T, Schuffenhauer A, Ertl P, Renner S.
    J Chem Inf Model; 2011 Jul 25; 51(7):1528-38. PubMed ID: 21615076
    [Abstract] [Full Text] [Related]

  • 15. Chemical biology--identification of small molecule modulators of cellular activity by natural product inspired synthesis.
    Hübel K, Lessmann T, Waldmann H.
    Chem Soc Rev; 2008 Jul 25; 37(7):1361-74. PubMed ID: 18568162
    [Abstract] [Full Text] [Related]

  • 16. Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces.
    Kim J, Kim H, Park SB.
    J Am Chem Soc; 2014 Oct 22; 136(42):14629-38. PubMed ID: 25310802
    [Abstract] [Full Text] [Related]

  • 17. Natural products in parallel chemistry--novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from alpha-santonin.
    Schwarz O, Jakupovic S, Ambrosi HD, Haustedt LO, Mang C, Müller-Kuhrt L.
    J Comb Chem; 2007 Oct 22; 9(6):1104-13. PubMed ID: 17850107
    [Abstract] [Full Text] [Related]

  • 18. Diversity-oriented synthesis: producing chemical tools for dissecting biology.
    O' Connor CJ, Beckmann HS, Spring DR.
    Chem Soc Rev; 2012 Jun 21; 41(12):4444-56. PubMed ID: 22491328
    [Abstract] [Full Text] [Related]

  • 19. Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries.
    Shang S, Tan DS.
    Curr Opin Chem Biol; 2005 Jun 21; 9(3):248-58. PubMed ID: 15939326
    [Abstract] [Full Text] [Related]

  • 20. Interactive exploration of chemical space with Scaffold Hunter.
    Wetzel S, Klein K, Renner S, Rauh D, Oprea TI, Mutzel P, Waldmann H.
    Nat Chem Biol; 2009 Aug 21; 5(8):581-3. PubMed ID: 19561620
    [Abstract] [Full Text] [Related]

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