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Journal Abstract Search

323 related items for PubMed ID: 22048522

  • 1. Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
    Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Ohshita H, Tateno C, Horie T, Kitamura S, Ohta S.
    Drug Metab Dispos; 2012 Feb; 40(2):322-8. PubMed ID: 22048522
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  • 8. Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes.
    Tanoue C, Sugihara K, Uramaru N, Tayama Y, Watanabe Y, Horie T, Ohta S, Kitamura S.
    Xenobiotica; 2013 Nov; 43(11):956-62. PubMed ID: 23651075
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  • 10. Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver.
    Kitamura S, Sugihara K.
    Xenobiotica; 2014 Jan; 44(2):123-34. PubMed ID: 24329499
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  • 11. Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics.
    Sanoh S, Ohta S.
    Biopharm Drug Dispos; 2014 Mar; 35(2):71-86. PubMed ID: 24114658
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  • 19. Evaluation of recombinant cytochrome P450 enzymes as an in vitro system for metabolic clearance predictions.
    Stringer RA, Strain-Damerell C, Nicklin P, Houston JB.
    Drug Metab Dispos; 2009 May; 37(5):1025-34. PubMed ID: 19196847
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