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342 related items for PubMed ID: 22050790

  • 1. Inhibition of JAK2/STAT3 signalling induces colorectal cancer cell apoptosis via mitochondrial pathway.
    Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su WY, Lin YW, Lu R, Zou WP, Xiong H, Fang JY.
    J Cell Mol Med; 2012 Aug; 16(8):1878-88. PubMed ID: 22050790
    [Abstract] [Full Text] [Related]

  • 2. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.
    Clin Exp Pharmacol Physiol; 2010 Aug; 37(8):833-40. PubMed ID: 20456425
    [Abstract] [Full Text] [Related]

  • 3. Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study.
    Tantawy MA, El-Sherbeeny NA, Helmi N, Alazragi R, Salem N, Elaidy SM.
    Mol Cell Biochem; 2020 Jun; 469(1-2):143-157. PubMed ID: 32356241
    [Abstract] [Full Text] [Related]

  • 4. Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway.
    Liu Y, Wang L, Wu Y, Lv C, Li X, Cao X, Yang M, Feng D, Luo Z.
    Toxicology; 2013 Feb 08; 304():120-31. PubMed ID: 23313376
    [Abstract] [Full Text] [Related]

  • 5. JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
    Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.
    Phytomedicine; 2019 Jan 08; 52():60-69. PubMed ID: 30599913
    [Abstract] [Full Text] [Related]

  • 6. Overexpression of B7-H3 augments anti-apoptosis of colorectal cancer cells by Jak2-STAT3.
    Zhang T, Jiang B, Zou ST, Liu F, Hua D.
    World J Gastroenterol; 2015 Feb 14; 21(6):1804-13. PubMed ID: 25684945
    [Abstract] [Full Text] [Related]

  • 7. Knockdown of TRIM66 inhibits cell proliferation, migration and invasion in colorectal cancer through JAK2/STAT3 pathway.
    He T, Cui J, Wu Y, Sun X, Chen N.
    Life Sci; 2019 Oct 15; 235():116799. PubMed ID: 31472144
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.
    Xiong H, Zhang ZG, Tian XQ, Sun DF, Liang QC, Zhang YJ, Lu R, Chen YX, Fang JY.
    Neoplasia; 2008 Mar 15; 10(3):287-97. PubMed ID: 18320073
    [Abstract] [Full Text] [Related]

  • 9. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW, Kundu J, Chae IG, Kim DH, Yu MH, Kundu JK, Chun KS.
    Int J Oncol; 2014 Apr 15; 44(4):1309-15. PubMed ID: 24481553
    [Abstract] [Full Text] [Related]

  • 10. Exercise-induced peptide EIP-22 protect myocardial from ischaemia/reperfusion injury via activating JAK2/STAT3 signalling pathway.
    Zhang L, Wang X, Zhang H, Feng M, Ding J, Zhang B, Cheng Z, Qian L.
    J Cell Mol Med; 2021 Apr 15; 25(7):3560-3572. PubMed ID: 33710777
    [Abstract] [Full Text] [Related]

  • 11. Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB.
    Marrero MB, Bencherif M.
    Brain Res; 2009 Feb 23; 1256():1-7. PubMed ID: 19063868
    [Abstract] [Full Text] [Related]

  • 12. Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
    Lee MH, Hong SH, Park C, Kim GY, Leem SH, Choi SH, Keum YS, Hyun JW, Kwon TK, Hong SH, Choi YH.
    Oncol Rep; 2016 Jul 23; 36(1):205-14. PubMed ID: 27221553
    [Abstract] [Full Text] [Related]

  • 13. Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling.
    Zhu F, Dai C, Fu Y, Loo JF, Xia D, Gao SP, Ma Z, Chen Z.
    Oncotarget; 2016 Feb 23; 7(8):9462-76. PubMed ID: 26843613
    [Abstract] [Full Text] [Related]

  • 14. Adiponectin Attenuates Oxygen-Glucose Deprivation-Induced Mitochondrial Oxidative Injury and Apoptosis in Hippocampal HT22 Cells via the JAK2/STAT3 Pathway.
    Wang B, Guo H, Li X, Yue L, Liu H, Zhao L, Bai H, Liu X, Wu X, Qu Y.
    Cell Transplant; 2018 Dec 23; 27(12):1731-1743. PubMed ID: 29947255
    [Abstract] [Full Text] [Related]

  • 15. Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
    Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R.
    PLoS One; 2012 Dec 23; 7(11):e49306. PubMed ID: 23166634
    [Abstract] [Full Text] [Related]

  • 16. Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer.
    Cao Y, Wang J, Tian H, Fu GH.
    J Exp Clin Cancer Res; 2020 Jun 23; 39(1):119. PubMed ID: 32576206
    [Abstract] [Full Text] [Related]

  • 17. Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/STAT3/GPX4 axis.
    Lai JQ, Zhao LL, Hong C, Zou QM, Su JX, Li SJ, Zhou XF, Li ZS, Deng B, Cao J, Qi Q.
    Acta Pharmacol Sin; 2024 Aug 23; 45(8):1715-1726. PubMed ID: 38684798
    [Abstract] [Full Text] [Related]

  • 18. Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231 cancer cells.
    Lin KL, Su JC, Chien CM, Chuang PW, Chang LS, Lin SR.
    Toxicon; 2010 Jun 15; 55(7):1263-73. PubMed ID: 20144642
    [Abstract] [Full Text] [Related]

  • 19. The HOTAIR/miR-214/ST6GAL1 crosstalk modulates colorectal cancer procession through mediating sialylated c-Met via JAK2/STAT3 cascade.
    Liu B, Liu Q, Pan S, Huang Y, Qi Y, Li S, Xiao Y, Jia L.
    J Exp Clin Cancer Res; 2019 Nov 06; 38(1):455. PubMed ID: 31694696
    [Abstract] [Full Text] [Related]

  • 20. Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway.
    Kim DH, Park JE, Chae IG, Park G, Lee S, Chun KS.
    Oncol Rep; 2017 Jul 06; 38(1):575-583. PubMed ID: 28560439
    [Abstract] [Full Text] [Related]

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