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Journal Abstract Search

291 related items for PubMed ID: 22052725

  • 1. Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases.
    Schmidt MF, Groves MR, Rademann J.
    Chembiochem; 2011 Nov 25; 12(17):2640-6. PubMed ID: 22052725
    [Abstract] [Full Text] [Related]

  • 2. Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.
    Maccari R, Ottanà R, Ciurleo R, Paoli P, Manao G, Camici G, Laggner C, Langer T.
    ChemMedChem; 2009 Jun 25; 4(6):957-62. PubMed ID: 19288492
    [Abstract] [Full Text] [Related]

  • 3. Allele-specific inhibitors of protein tyrosine phosphatases.
    Hoffman HE, Blair ER, Johndrow JE, Bishop AC.
    J Am Chem Soc; 2005 Mar 09; 127(9):2824-5. PubMed ID: 15740097
    [Abstract] [Full Text] [Related]

  • 4. 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.
    Ottanà R, Maccari R, Ciurleo R, Paoli P, Jacomelli M, Manao G, Camici G, Laggner C, Langer T.
    Bioorg Med Chem; 2009 Mar 01; 17(5):1928-37. PubMed ID: 19217304
    [Abstract] [Full Text] [Related]

  • 5. Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.
    Liu G, Xin Z, Liang H, Abad-Zapatero C, Hajduk PJ, Janowick DA, Szczepankiewicz BG, Pei Z, Hutchins CW, Ballaron SJ, Stashko MA, Lubben TH, Berg CE, Rondinone CM, Trevillyan JM, Jirousek MR.
    J Med Chem; 2003 Jul 31; 46(16):3437-40. PubMed ID: 12877578
    [Abstract] [Full Text] [Related]

  • 6. The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.
    Scapin G, Patel SB, Becker JW, Wang Q, Desponts C, Waddleton D, Skorey K, Cromlish W, Bayly C, Therien M, Gauthier JY, Li CS, Lau CK, Ramachandran C, Kennedy BP, Asante-Appiah E.
    Biochemistry; 2003 Oct 07; 42(39):11451-9. PubMed ID: 14516196
    [Abstract] [Full Text] [Related]

  • 7. Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
    Liu G, Xin Z, Pei Z, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Zhao H, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR.
    J Med Chem; 2003 Sep 25; 46(20):4232-5. PubMed ID: 13678400
    [Abstract] [Full Text] [Related]

  • 8. Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
    Szczepankiewicz BG, Liu G, Hajduk PJ, Abad-Zapatero C, Pei Z, Xin Z, Lubben TH, Trevillyan JM, Stashko MA, Ballaron SJ, Liang H, Huang F, Hutchins CW, Fesik SW, Jirousek MR.
    J Am Chem Soc; 2003 Apr 09; 125(14):4087-96. PubMed ID: 12670229
    [Abstract] [Full Text] [Related]

  • 9. Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor.
    Liu GX, Tan JZ, Niu CY, Shen JH, Luo XM, Shen X, Chen KX, Jiang HL.
    Acta Pharmacol Sin; 2006 Jan 09; 27(1):100-10. PubMed ID: 16364216
    [Abstract] [Full Text] [Related]

  • 10. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases.
    Welte S, Baringhaus KH, Schmider W, Müller G, Petry S, Tennagels N.
    Anal Biochem; 2005 Mar 01; 338(1):32-8. PubMed ID: 15707933
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and inhibition activity of novel cyclic peptides against protein tyrosine phosphatase A from Mycobacterium tuberculosis.
    Chandra K, Dutta D, Das AK, Basak A.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8365-73. PubMed ID: 21050767
    [Abstract] [Full Text] [Related]

  • 12. Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site.
    Mustelin T, Tautz L, Page R.
    J Mol Biol; 2005 Nov 18; 354(1):150-63. PubMed ID: 16226275
    [Abstract] [Full Text] [Related]

  • 13. Dinuclear copper complexes of organic claw: potent inhibition of protein tyrosine phosphatases.
    Ma L, Lu L, Zhu M, Wang Q, Gao F, Yuan C, Wu Y, Xing S, Fu X, Mei Y, Gao X.
    J Inorg Biochem; 2011 Sep 18; 105(9):1138-47. PubMed ID: 21708098
    [Abstract] [Full Text] [Related]

  • 14. Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.
    Stuible M, Zhao L, Aubry I, Schmidt-Arras D, Böhmer FD, Li CJ, Tremblay ML.
    Chembiochem; 2007 Jan 22; 8(2):179-86. PubMed ID: 17191286
    [Abstract] [Full Text] [Related]

  • 15. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.
    Manger M, Scheck M, Prinz H, von Kries JP, Langer T, Saxena K, Schwalbe H, Fürstner A, Rademann J, Waldmann H.
    Chembiochem; 2005 Oct 22; 6(10):1749-53. PubMed ID: 16196020
    [No Abstract] [Full Text] [Related]

  • 16. Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development.
    Zhang ZY.
    Annu Rev Pharmacol Toxicol; 2002 Oct 22; 42():209-34. PubMed ID: 11807171
    [Abstract] [Full Text] [Related]

  • 17. A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).
    Drake PG, Peters GH, Andersen HS, Hendriks W, Møller NP.
    Biochem J; 2003 Jul 15; 373(Pt 2):393-401. PubMed ID: 12697028
    [Abstract] [Full Text] [Related]

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  • 19. Molecular dynamics studies on the interactions of PTP1B with inhibitors: from the first phosphate-binding site to the second one.
    Wang JF, Gong K, Wei DQ, Li YX, Chou KC.
    Protein Eng Des Sel; 2009 Jun 15; 22(6):349-55. PubMed ID: 19380334
    [Abstract] [Full Text] [Related]

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