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Journal Abstract Search

276 related items for PubMed ID: 22057163

  • 1. Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.
    Shekh-Ahmad T, Bialer M, Yavin E.
    Epilepsy Res; 2012 Feb; 98(2-3):238-46. PubMed ID: 22057163
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  • 2. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2009 Apr 23; 52(8):2233-42. PubMed ID: 19296679
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  • 3. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
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  • 4. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul 12; 49(7):1202-12. PubMed ID: 18435754
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  • 5. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
    Epilepsia; 2014 Dec 12; 55(12):1944-52. PubMed ID: 25442425
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  • 6. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar 12; 51(3):323-32. PubMed ID: 19674061
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  • 7. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
    Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsy Behav; 2011 Nov 12; 22(3):461-8. PubMed ID: 21959082
    [Abstract] [Full Text] [Related]

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  • 9. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M.
    Neuropharmacology; 2006 Sep 12; 51(4):933-46. PubMed ID: 16890251
    [Abstract] [Full Text] [Related]

  • 10. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
    Gravemann U, Volland J, Nau H.
    Neurotoxicol Teratol; 2008 Sep 12; 30(5):390-4. PubMed ID: 18455366
    [Abstract] [Full Text] [Related]

  • 11. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.
    Hen N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2010 May 27; 53(10):4177-86. PubMed ID: 20420384
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  • 14. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
    Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M.
    Epilepsy Res; 2007 Jan 27; 73(1):75-84. PubMed ID: 16997532
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  • 16. Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.
    Winkler I, Sobol E, Yagen B, Steinman A, Devor M, Bialer M.
    Neuropharmacology; 2005 Dec 27; 49(8):1110-20. PubMed ID: 16055160
    [Abstract] [Full Text] [Related]

  • 17. Assessment of seizure susceptibility in pilocarpine epileptic and nonepileptic Wistar rats and of seizure reinduction with pentylenetetrazole and electroshock models.
    Blanco MM, dos Santos JG, Perez-Mendes P, Kohek SR, Cavarsan CF, Hummel M, Albuquerque C, Mello LE.
    Epilepsia; 2009 Apr 27; 50(4):824-31. PubMed ID: 19054404
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  • 19. Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea.
    Tantisira B, Tantisira MH, Patarapanich C, Sooksawate T, Chunngam T.
    Res Commun Mol Pathol Pharmacol; 1997 Aug 27; 97(2):151-64. PubMed ID: 9344228
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  • 20. Synthesis and anticonvulsant activity of new 6-methyl-1-substituted-4,6-diazaspiro[2.4]heptane-5,7-diones.
    He X, Qiu G, Yang J, Xiao Y, Wu Z, Qiu G, Hu X.
    Eur J Med Chem; 2010 Sep 27; 45(9):3818-30. PubMed ID: 20542603
    [Abstract] [Full Text] [Related]

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