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Journal Abstract Search

192 related items for PubMed ID: 22057724

  • 1. mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.
    Zhang Z, Zhang G, Xu X, Su W, Yu B.
    Mol Cell Biochem; 2012 Feb; 361(1-2):249-57. PubMed ID: 22057724
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  • 4. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
    Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.
    Science; 2005 Feb 18; 307(5712):1098-101. PubMed ID: 15718470
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  • 6. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F.
    J Endocrinol; 2013 Jan 18; 216(1):21-9. PubMed ID: 23092880
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  • 8. Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.
    Lee SL, Chou CC, Chuang HC, Hsu EC, Chiu PC, Kulp SK, Byrd JC, Chen CS.
    PLoS One; 2013 Jan 18; 8(6):e67149. PubMed ID: 23840605
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  • 9. F-actin rearrangement is regulated by mTORC2/Akt/Girdin in mouse fertilized eggs.
    Wu D, Yu D, Wang X, Yu B.
    Cell Prolif; 2016 Dec 18; 49(6):740-750. PubMed ID: 27666957
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  • 10. Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.
    Wang X, Yue P, Kim YA, Fu H, Khuri FR, Sun SY.
    Cancer Res; 2008 Sep 15; 68(18):7409-18. PubMed ID: 18794129
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  • 11. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA, Carriere A, Moreau J, Roux PP.
    Mol Cell Biol; 2010 Feb 15; 30(4):908-21. PubMed ID: 19995915
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  • 12. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH, Park YH, Kwon JH, Lee JH, Kim IY.
    Biochim Biophys Acta; 2013 Oct 15; 1833(10):2135-42. PubMed ID: 23680186
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  • 13. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM.
    Dev Cell; 2006 Dec 15; 11(6):859-71. PubMed ID: 17141160
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  • 14. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin.
    Toschi A, Lee E, Xu L, Garcia A, Gadir N, Foster DA.
    Mol Cell Biol; 2009 Mar 15; 29(6):1411-20. PubMed ID: 19114562
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  • 15. Rictor, an mTORC2 Protein, Regulates Murine Lymphatic Valve Formation Through the AKT-FOXO1 Signaling.
    Banerjee R, Knauer LA, Iyer D, Barlow SE, Shalaby H, Dehghan R, Scallan JP, Yang Y.
    Arterioscler Thromb Vasc Biol; 2024 Sep 15; 44(9):2004-2023. PubMed ID: 39087350
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  • 16. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M.
    Int J Oncol; 2009 Oct 15; 35(4):731-40. PubMed ID: 19724909
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  • 17. Akt and PKC are involved not only in upregulation of telomerase activity but also in cell differentiation-related function via mTORC2 in leukemia cells.
    Yamada O, Ozaki K, Nakatake M, Kakiuchi Y, Akiyama M, Mitsuishi T, Kawauchi K, Matsuoka R.
    Histochem Cell Biol; 2010 Dec 15; 134(6):555-63. PubMed ID: 21086135
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  • 18. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
    Hou G, Zhao Q, Zhang M, Fan T, Liu M, Shi X, Ren Y, Wang Y, Zhou J, Lu Z.
    Biomed Pharmacother; 2018 Oct 15; 106():1348-1356. PubMed ID: 30119206
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  • 19. Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
    Zeng Z, Sarbassov dos D, Samudio IJ, Yee KW, Munsell MF, Ellen Jackson C, Giles FJ, Sabatini DM, Andreeff M, Konopleva M.
    Blood; 2007 Apr 15; 109(8):3509-12. PubMed ID: 17179228
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  • 20. Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.
    Brown J, Wang H, Suttles J, Graves DT, Martin M.
    J Biol Chem; 2011 Dec 30; 286(52):44295-305. PubMed ID: 22045807
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