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Journal Abstract Search

340 related items for PubMed ID: 22058153

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  • 4. In vivo efficacy of the AKT inhibitor ARQ 092 in Noonan Syndrome with multiple lentigines-associated hypertrophic cardiomyopathy.
    Wang J, Chandrasekhar V, Abbadessa G, Yu Y, Schwartz B, Kontaridis MI.
    PLoS One; 2017; 12(6):e0178905. PubMed ID: 28582432
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  • 8. New approaches to prevent LEOPARD syndrome-associated cardiac hypertrophy by specifically targeting Shp2-dependent signaling.
    Schramm C, Edwards MA, Krenz M.
    J Biol Chem; 2013 Jun 21; 288(25):18335-44. PubMed ID: 23673659
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  • 13. mTOR pathway in human cardiac hypertrophy caused by LEOPARD syndrome: a different role compared with animal models?
    Cui H, Song L, Zhu C, Zhang C, Tang B, Wang S, Wu G, Zou Y, Huang X, Hui R, Wang S, Wang J.
    Orphanet J Rare Dis; 2019 Nov 13; 14(1):252. PubMed ID: 31722741
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  • 14. Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.
    Coppini R, Mazzoni L, Ferrantini C, Gentile F, Pioner JM, Laurino A, Santini L, Bargelli V, Rotellini M, Bartolucci G, Crocini C, Sacconi L, Tesi C, Belardinelli L, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Poggesi C.
    Circ Heart Fail; 2017 Mar 13; 10(3):. PubMed ID: 28255011
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  • 15. Inhibition of mammalian target of rapamycin with rapamycin reverses hypertrophic cardiomyopathy in mice with cardiomyocyte-specific knockout of PTEN.
    Xu X, Roe ND, Weiser-Evans MC, Ren J.
    Hypertension; 2014 Apr 13; 63(4):729-39. PubMed ID: 24446058
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  • 16. Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish.
    Bonetti M, Paardekooper Overman J, Tessadori F, Noël E, Bakkers J, den Hertog J.
    Development; 2014 May 13; 141(9):1961-70. PubMed ID: 24718990
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  • 18. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes.
    Ramachandra CJA, Kp MMJ, Chua J, Hernandez-Resendiz S, Liehn EA, Knöll R, Gan LM, Michaëlsson E, Jonsson MKB, Ryden-Markinhuhta K, Bhat RV, Fritsche-Danielson R, Lin YH, Sadayappan S, Tang HC, Wong P, Shim W, Hausenloy DJ.
    Cardiovasc Res; 2022 Jan 29; 118(2):517-530. PubMed ID: 33705529
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  • 19. Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines.
    Lauriol J, Cabrera JR, Roy A, Keith K, Hough SM, Damilano F, Wang B, Segarra GC, Flessa ME, Miller LE, Das S, Bronson R, Lee KH, Kontaridis MI.
    J Clin Invest; 2016 Aug 01; 126(8):2989-3005. PubMed ID: 27348588
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  • 20. Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.
    Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG.
    Circulation; 2008 Mar 18; 117(11):1423-35. PubMed ID: 18316486
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