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Journal Abstract Search


209 related items for PubMed ID: 22061827

  • 1. Ovarian expressed microsomal epoxide hydrolase: role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling.
    Bhattacharya P, Sen N, Hoyer PB, Keating AF.
    Toxicol Appl Pharmacol; 2012 Jan 01; 258(1):118-23. PubMed ID: 22061827
    [Abstract] [Full Text] [Related]

  • 2. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure.
    Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB.
    Toxicol Sci; 2008 Oct 01; 105(2):351-9. PubMed ID: 18622027
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system.
    Igawa Y, Keating AF, Rajapaksa KS, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2009 Feb 01; 234(3):361-9. PubMed ID: 19027032
    [Abstract] [Full Text] [Related]

  • 4. Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries.
    Keating AF, J Mark C, Sen N, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2009 Dec 01; 241(2):127-34. PubMed ID: 19695275
    [Abstract] [Full Text] [Related]

  • 5. Expression and activity of microsomal epoxide hydrolase in follicles isolated from mouse ovaries.
    Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Sci; 2002 Jul 01; 68(1):24-31. PubMed ID: 12075107
    [Abstract] [Full Text] [Related]

  • 6. Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F(1) mice.
    Keating AF, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2008 Jul 01; 230(1):109-16. PubMed ID: 18407309
    [Abstract] [Full Text] [Related]

  • 7. Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat.
    Springer LN, Tilly JL, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1996 Aug 01; 139(2):402-10. PubMed ID: 8806858
    [Abstract] [Full Text] [Related]

  • 8. involvement of microsomal epoxide hydrolase enzyme in ovotoxicity caused by 7,12-dimethylbenz[a]anthracene.
    Rajapaksa KS, Sipes IG, Hoyer PB.
    Toxicol Sci; 2007 Apr 01; 96(2):327-34. PubMed ID: 17204581
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of PIK3 signaling pathway members by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.
    Keating AF, Fernandez SM, Mark-Kappeler CJ, Sen N, Sipes IG, Hoyer PB.
    Biol Reprod; 2011 Apr 01; 84(4):743-51. PubMed ID: 21076081
    [Abstract] [Full Text] [Related]

  • 10. Expression and activity of cytochromes P450 2E1, 2A, and 2B in the mouse ovary: the effect of 4-vinylcyclohexene and its diepoxide metabolite.
    Cannady EA, Dyer CA, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Sci; 2003 Jun 01; 73(2):423-30. PubMed ID: 12700394
    [Abstract] [Full Text] [Related]

  • 11. Glutathione S-transferase class μ regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries.
    Bhattacharya P, Madden JA, Sen N, Hoyer PB, Keating AF.
    Toxicol Appl Pharmacol; 2013 Feb 15; 267(1):49-56. PubMed ID: 23274565
    [Abstract] [Full Text] [Related]

  • 12. Characterization of a rat in vitro ovarian culture system to study the ovarian toxicant 4-vinylcyclohexene diepoxide.
    Devine PJ, Sipes IG, Skinner MK, Hoyer PB.
    Toxicol Appl Pharmacol; 2002 Oct 15; 184(2):107-15. PubMed ID: 12408955
    [Abstract] [Full Text] [Related]

  • 13. Distribution and responsiveness of rat anti-Müllerian hormone during ovarian development and VCD-induced ovotoxicity.
    Mark-Kappeler CJ, Sen N, Keating AF, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2010 Nov 15; 249(1):1-7. PubMed ID: 20816688
    [Abstract] [Full Text] [Related]

  • 14. Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index.
    Borman SM, Christian PJ, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2000 Sep 15; 167(3):191-8. PubMed ID: 10986010
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of ovarian KIT phosphorylation by the ovotoxicant 4-vinylcyclohexene diepoxide in rats.
    Mark-Kappeler CJ, Sen N, Lukefahr A, McKee L, Sipes IG, Konhilas J, Hoyer PB.
    Biol Reprod; 2011 Oct 15; 85(4):755-62. PubMed ID: 21677306
    [Abstract] [Full Text] [Related]

  • 16. Dual protective role for glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary.
    Keating AF, Sen N, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 2010 Sep 01; 247(2):71-5. PubMed ID: 20542051
    [Abstract] [Full Text] [Related]

  • 17. Reduced ability of rat preantral ovarian follicles to metabolize 4-vinyl-1-cyclohexene diepoxide in vitro.
    Flaws JA, Salyers KL, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1994 Jun 01; 126(2):286-94. PubMed ID: 8209381
    [Abstract] [Full Text] [Related]

  • 18. Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.
    Springer LN, McAsey ME, Flaws JA, Tilly JL, Sipes IG, Hoyer PB.
    Toxicol Appl Pharmacol; 1996 Aug 01; 139(2):394-401. PubMed ID: 8806857
    [Abstract] [Full Text] [Related]

  • 19. Activation of mitogen-activated protein kinases and AP-1 transcription factor in ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats.
    Hu X, Flaws JA, Sipes IG, Hoyer PB.
    Biol Reprod; 2002 Sep 01; 67(3):718-24. PubMed ID: 12193377
    [Abstract] [Full Text] [Related]

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